Search Hotels in East Seneca, Buffalo

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for East Seneca hotels

Clarence Inn

Clarence Inn
2.0 star property
15.6 km from East Seneca
8.2 out of 10, Very good, (297 reviews)
"Great service quiet place and friendly people."
United States
Larry
The price is ฿3,155
฿3,526 total
includes taxes & fees
9 Mar - 10 Mar
Clarence Inn

Asa Ransom House

Asa Ransom House
3.0 star property
18.7 km from East Seneca
9.6 out of 10, Exceptional, (207 reviews)
"Amazing breakfast. Charming property. Excellent host."
United States
tamra
The price is ฿4,579
฿5,372 total
includes taxes & fees
9 Mar - 10 Mar
Asa Ransom House

The Fields of Eden Inn

The Fields of Eden Inn
3.5 star property
25.4 km from East Seneca
9.8 out of 10, Exceptional, (96 reviews)
"Beautiful room, very comfortable, great location. Will definitely come back for future trips."
United States
Mark
The price is ฿5,418
฿6,055 total
includes taxes & fees
9 Mar - 10 Mar
The Fields of Eden Inn

Fels Three Crown Motel

Fels Three Crown Motel
2.0 star property
18.1 km from East Seneca
7.6 out of 10, Good, (251 reviews)
"Another great stay!"
United States
KURT
The price is ฿2,518
฿2,814 total
includes taxes & fees
9 Mar - 10 Mar
Fels Three Crown Motel

Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG
2.5 star property
28.7 km from East Seneca
9.2 out of 10, Wonderful, (763 reviews)
"Clean and comfortable accommodations, friendly staff and a great breakfast spread!"
United States
Andrea
The price is ฿3,665
฿4,142 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Amherst - Lockport by IHG

Staybridge Suites West Seneca by IHG

Staybridge Suites West Seneca by IHG
3.0 star property
6.4 km from East Seneca
9.0 out of 10, Wonderful, (875 reviews)
"So extremely clean, quiet, spacious and a great breakfast in the morning!"
United States
Julia
The price is ฿5,418
฿6,163 total
includes taxes & fees
10 Mar - 11 Mar
Staybridge Suites West Seneca by IHG

Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90
2.5 star property
6.2 km from East Seneca
8.6 out of 10, Excellent, (1,004 reviews)
"Room was very clean and comfortable. Staff was helpful. Pool was a lot of fun. "
United States
Bonnie
The price is ฿3,633
฿4,132 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Buffalo South/I-90

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
4.0 star property
14.5 km from East Seneca
9.4 out of 10, Exceptional, (1,002 reviews)
"Really enjoyed this hotel. Very very very clean and tidy. Great staff and very quiet. Would definitely stay again "
Canada
Naomi
The price is ฿4,548
฿5,173 total
includes taxes & fees
29 Mar - 30 Mar
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG
2.5 star property
18.5 km from East Seneca
8.6 out of 10, Excellent, (972 reviews)
"Good size room, very clean. Courteous staff Full size refrigerator , dishwasher, coffee pot - cutlery, and a good location. "
United States
Julia
The price is ฿3,602
฿4,097 total
includes taxes & fees
22 Mar - 23 Mar
Candlewood Suites Buffalo - Amherst by IHG

Summer Street Guest House

Summer Street Guest House
3.0 star property
Bryant, 15.7 km from East Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Charles greeted us upon arrival and took us on a tour of his beautiful house. It was magnificent. Spacious and well-appointed. A terrific stay!"
Canada
Anthony
The price is ฿11,446
฿16,791 total
includes taxes & fees
9 Mar - 10 Mar
Summer Street Guest House

Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel
4.0 star property
14.7 km from East Seneca
9.6 out of 10, Exceptional, (695 reviews)
"Very nice hotel, well maintained, clean and high class. "
United States
Brian
The price is ฿5,132
฿5,837 total
includes taxes & fees
14 Mar - 15 Mar
Reikart House, Buffalo, a Tribute Portfolio Hotel

Home2 Suites by Hilton Amherst Buffalo

Home2 Suites by Hilton Amherst Buffalo
3.0 star property
20.6 km from East Seneca
8.8 out of 10, Excellent, (1,001 reviews)
"Nice stay, good location"
United States
kristine
The price is ฿3,894
฿4,430 total
includes taxes & fees
5 Apr - 6 Apr
Home2 Suites by Hilton Amherst Buffalo

CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda
2.0 star property
22 km from East Seneca
7.8 out of 10, Good, (1,003 reviews)
"Another great stay!"
United States
KURT
The price is ฿2,230
฿2,536 total
includes taxes & fees
9 Mar - 10 Mar
CenterWay Hotel Tonawanda

Holiday Inn Express Hotel & Suites Hamburg by IHG

Holiday Inn Express Hotel & Suites Hamburg by IHG
2.5 star property
15.5 km from East Seneca
8.8 out of 10, Excellent, (1,005 reviews)
"Great room breakfast was good always a good stay "
United States
Robert
The price is ฿3,697
฿4,206 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Hotel & Suites Hamburg by IHG

Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Fairfield Inn & Suites by Marriott Buffalo Amherst/University
3.0 star property
19.4 km from East Seneca
8.8 out of 10, Excellent, (713 reviews)
"Room was clean, staff was nice, both check-in and check-out were seamless. "
Canada
Taaj
The price is ฿3,251
฿3,698 total
includes taxes & fees
29 Mar - 30 Mar
Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG
3.0 star property
19.4 km from East Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"The breakfast was amazing, the staff are extremely caring and friendly"
Canada
Sarah
The price is ฿4,303
฿4,895 total
includes taxes & fees
10 Mar - 11 Mar
Staybridge Suites Buffalo-Amherst by IHG

Hampton Inn East Aurora

Hampton Inn East Aurora
2.5 star property
11.4 km from East Seneca
9.4 out of 10, Exceptional, (1,000 reviews)
"Incredibly friendly staff at check in. Room was beautiful and very clean. "
United States
Linda
The price is ฿3,894
฿4,430 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn East Aurora

Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg
2.5 star property
15.2 km from East Seneca
9.0 out of 10, Wonderful, (1,001 reviews)
"Stay was comfortable and good food."
United States
David
The price is ฿3,209
฿3,651 total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn Buffalo-Hamburg

Roycroft Inn

Roycroft Inn
3.5 star property
10.8 km from East Seneca
9.6 out of 10, Exceptional, (861 reviews)
"Love this hotel! Large rooms, incredible craftsman style decor, and great staff."
United States
Shawn
Roycroft Inn

Comfort Inn & Suites Hamburg - Buffalo South

Comfort Inn & Suites Hamburg - Buffalo South
2.5 star property
15.4 km from East Seneca
7.2 out of 10, Good, (1,007 reviews)
"Room was clean, spacious and quiet. 10/10 would definitely stay here again as my first choice "
United States
Tony
The price is ฿3,049
฿3,469 total
includes taxes & fees
5 Apr - 6 Apr
Comfort Inn & Suites Hamburg - Buffalo South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Seneca

Find the best East Seneca areas for the activities you enjoy most.

Downtown Buffalo

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Buffalo Theater District

Theatres, live music and restaurants highlight some notable features of Buffalo Theater District. Make a stop by Shea's Performing Arts Center or Chippewa District while you're visiting, and jump aboard the metro at Fountain Plaza Station or Lafayette Square Station to get around town.

Elmwood Village

Elmwood Village is known for its live music, and you can plan a trip to Blue Sky Mausoleum and American Repertory Theater of WNY Performance Venue: The Compass Performing Arts Center while you're in town.

North Buffalo

North Buffalo is well liked for its live music and zoo. If you're hoping to get in some sightseeing, Buffalo Zoo and Buffalo AKG Art Museum are top spots, and you can jump on the metro at Amherst Street Station or Lasalle Station to get around.

Allentown

Allentown is noteworthy for its restaurants, and you can make a stop at top attractions like Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and Theater of Youth.

Top East Seneca Hotel Reviews

Frequently asked questions

What is East Seneca like?
Travellers will be sure to enjoy their time in West Seneca's East Seneca neighbourhood.
If I need to cancel my hotel reservation in East Seneca, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals in East Seneca.
What is there to do in this West Seneca neighbourhood?
A few places to visit in the area around East Seneca include Southgate Plaza, Harvest Hill Golf Course and Charles E. Burchfield Nature and Art Center. When you're sightseeing around the area, Holiday Twin Rinks and Knox Farm State Park are a couple of other sights to visit.