Penrose Travel Guide

St. Louis


Popular places to visit

Things to do


Top hotels in Penrose

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is ฿4,457 per night from 10 Feb to 11 Feb
฿4,457
฿5,367 total
10 Feb - 11 Feb
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (1,555 reviews)
Great Location, great atmosphere. Drinks and food on the floor level, beautiful artwork is on display.

Reviewed on 18 Jan 2026

21C Museum Hotel St Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is ฿4,623 per night from 24 Jan to 25 Jan
฿4,623
฿5,452 total
24 Jan - 25 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,041 reviews)
The room is perfect. The queen bed room is the best value for the single traveler. The only problem is having a problem to adjust the hot water in the sink.

Reviewed on 17 Jan 2026

Hyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
The price is ฿2,708 per night from 25 Jan to 26 Jan
฿2,708
฿3,221 total
25 Jan - 26 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,202 reviews)
Everything was great the customer service rep at the desk exceptional customer service.

Reviewed on 18 Jan 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿2,790 per night from 30 Jan to 31 Jan
฿2,790
฿3,257 total
30 Jan - 31 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,080 reviews)
The room was great and the staff professional and friendly. The breakfast is always fabulous.

Reviewed on 18 Jan 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is ฿2,792 per night from 26 Jan to 27 Jan
฿2,792
฿3,287 total
26 Jan - 27 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (2,783 reviews)
It was very clean. The staff were all friendly and efficient! Breakfast was good and the bed was so comfortable. I would definitely recommend!

Reviewed on 17 Jan 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,064 per night from 26 Jan to 27 Jan
฿4,064
฿4,752 total
26 Jan - 27 Jan
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (3,315 reviews)
Everything was good. The staff was awesome, room very clean, food and drink was great.

Reviewed on 19 Jan 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Penrose

Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.

Midtown

While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

Midtown
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove
Heading west out of St Louis found this little waterfall on a side road just a couple of miles off the Interstate. Nice stop to stretch the legs. Quick stops off the Interstate can be both interesting and refreshing.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Downtown West
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The Gate

While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.

The Gate
Lafayette Square featuring a house and a park

Lafayette Square

The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.

Lafayette Square


Penrose Travel Guide