Downtown Clayton Travel Guide

St. Louis

A bronze bell with an eagle atop, surrounded by greenery and a street scene in the background.

Things to do


Top hotels in Downtown Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ฿3,135 per night from 12 Jul to 13 Jul
฿3,135
฿3,660 total
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (3,272 reviews)
"Great location Great breakfast"

Reviewed on 7 Jul 2026

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is ฿4,877 per night from 2 Aug to 3 Aug
฿4,877
฿5,693 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Popular attractions St. Louis Zoo and Saint Louis Galleria ...
9/10 Wonderful! (335 reviews)
"Staff is top notch. 11th floor bar is cool. Room was small yet comfortable and modern"

Reviewed on 30 Jun 2026

AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ฿5,330 per night from 11 Jul to 12 Jul
฿5,330
฿6,275 total
11 Jul - 12 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (738 reviews)
"Thoroughly enjoyed my stay! Convenient location"

Reviewed on 6 Jul 2026

Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is ฿16,555 per night from 26 Jul to 27 Jul
฿16,555
฿19,326 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the helpful staff and the room service ...
9.2/10 Wonderful! (573 reviews)
"Very nice property to stay at and a nice walk to Shaw Park."

Reviewed on 28 Jun 2026

The Ritz-Carlton, St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundable
The price is ฿5,062 per night from 9 Jul to 10 Jul
฿5,062
฿5,969 total
9 Jul - 10 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,188 reviews)
"good"

Reviewed on 6 Jul 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is ฿3,327 per night from 2 Aug to 3 Aug
฿3,327
฿3,917 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (3,072 reviews)
"Check out time was 11 but house keeping was tapping on our door around 7 then again around 9:15. The final appearance was around 10:45 which I would consider as a reminder that check out was soon. There was also a dog in the next room that was constantly barking early in the morning. I’ve stayed ..."

Reviewed on 7 Jul 2026

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.



Downtown Clayton Travel Guide