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Check prices for these dates

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8 Nov - 9 Nov
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9 Nov - 10 Nov
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13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Sanibel Isles hotels

A beach with a variety of seashells and pebbles.

1. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (2,417 reviews)
"It was a wonderful stay. We really enjoyed it."
United States
Elina
The price is ฿6,679
฿8,383 total
includes taxes & fees
9 Nov - 10 Nov
Sanibel Island Beach Resort
A pathway leading to a pool area with lounge chairs and umbrellas, surrounded by tropical plants and a thatched-roof structure.

2. Sanibel Inn

Sanibel Inn
3.0 star property
East End, 3.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,002 reviews)
"Staff was amazingly friendly"
United States
Tamara
The price is ฿10,177
฿13,481 total
includes taxes & fees
11 Nov - 12 Nov
Sanibel Inn
A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

3. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3.5 km from Sanibel Isles
8.6 out of 10, Excellent, (2,718 reviews)
"Love the resort and great access to beach"
United States
Lisa Renee
The price is ฿11,714
฿15,269 total
includes taxes & fees
29 Nov - 30 Nov
Sundial Beach Resort & Spa
Living area

4. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
10.0 out of 10, Exceptional, (85 reviews)
"The whole place was wonderful."
United States
April
The price is ฿5,606
฿6,755 total
includes taxes & fees
10 Nov - 11 Nov
The Anchor Inn
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

5. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
5.2 km from Sanibel Isles
8.6 out of 10, Excellent, (1,002 reviews)
"I love everything about this hotel"
United States
Yunior
The price is ฿7,492
฿9,528 total
includes taxes & fees
22 Nov - 23 Nov
Marriott Sanibel Harbour Resort & Spa
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

6. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 4.7 km from Sanibel Isles
9.0 out of 10, Wonderful, (481 reviews)
"Beautiful grounds, restaurant and bar very nice, good beach access"
Canada
Ronald
The price is ฿8,705
฿9,706 total
includes taxes & fees
9 Nov - 10 Nov
Casa Ybel Resort
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

7. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
3.5 star property
Mid Island, 2.9 km from Sanibel Isles
9.2 out of 10, Wonderful, (230 reviews)
"Nice and clean, has everything you need, in the kitchen particularly, 5 minute walk to the beach and the staff were lovely checking in every so often."
United Kingdom
Callie
The price is ฿9,365
฿10,442 total
includes taxes & fees
9 Nov - 10 Nov
THE Palmview AND Sandpiper Inns
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

8. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 km from Sanibel Isles
8.2 out of 10, Very good, (1,401 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is ฿2,685
฿2,994 total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A rustic outdoor bathroom with a wooden deck, a white sink, and various seashells scattered around.

9. Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End, 3.4 km from Sanibel Isles
9.6 out of 10, Exceptional, (413 reviews)
"Makes you feel at home. Impeccably kept. Joe and Maureen give attention to details and think of guest convenience and hospitality. Excellent location. Steps from beach and little stores. Sanibel is gorgeous and chill, and so is Tarpon Tales Inn."
United States
Marianella
The price is ฿7,686
฿8,570 total
includes taxes & fees
13 Nov - 14 Nov
Tarpon Tale Inn
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

10. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,003 reviews)
"Loved the balcony view, breakfast spread, hot tub and heated pool."
United States
Lora
The price is ฿3,424
฿3,817 total
includes taxes & fees
15 Nov - 16 Nov
Residence Inn by Marriott Fort Myers Sanibel
A large, clear swimming pool with multiple lounge areas and palm trees.

11. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
10.1 km from Sanibel Isles
9.0 out of 10, Wonderful, (2,742 reviews)
"Everything about the resort was excellent"
United States
Lance
The price is ฿6,011
฿8,388 total
includes taxes & fees
29 Nov - 30 Nov
Margaritaville Beach Resort Fort Myers
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

12. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (165 reviews)
"Very good on everything I love the location"
United States
George
The price is ฿5,311
฿7,045 total
includes taxes & fees
1 Dec - 2 Dec
Off the Charts Inn & Out Island Resort
A beach with a view of the ocean and a sunset.

13. Island Inn

Island Inn
3.5 star property
West End, 5.9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,168 reviews)
"Great location"
United States
Nicole
The price is ฿7,347
฿8,192 total
includes taxes & fees
10 Nov - 11 Nov
Island Inn
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

14. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
9.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,002 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is ฿7,272
฿8,108 total
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Beach Resort
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

15. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,491 reviews)
"It's nice place to stay"
United States
Mario
The price is ฿7,220
฿10,258 total
includes taxes & fees
15 Nov - 16 Nov
Pink Shell Beach Resort and Marina
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

16. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
12.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is ฿3,222
฿3,593 total
includes taxes & fees
16 Nov - 17 Nov
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A balcony with a table and chairs, large windows, and a view of the sea.

17. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
10.1 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,001 reviews)
"Very clean and nice place!"
United States
Charles
The price is ฿4,910
฿6,972 total
includes taxes & fees
15 Nov - 16 Nov
The Westin Cape Coral Resort At Marina Village
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

18. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
12 km from Sanibel Isles
8.8 out of 10, Excellent, (1,003 reviews)
"Overall great experience at my stay."
United States
Chris
The price is ฿3,124
฿3,483 total
includes taxes & fees
10 Nov - 11 Nov
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A wooden boardwalk leading to a beach with clear skies and calm waters.

19. Shalimar Beach Resort

Shalimar Beach Resort
3.5 star property
West End, 5.6 km from Sanibel Isles
9.8 out of 10, Exceptional, (110 reviews)
"Room was big and clean. Right on beach and nice pool area and chairs."
United States
JOHN
The price is ฿10,543
฿11,755 total
includes taxes & fees
9 Nov - 10 Nov
Shalimar Beach Resort
A balcony with wicker furniture, a view of a beach, and a clear sky.

20. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
8.8 out of 10, Excellent, (2,185 reviews)
"Excellent location"
United States
yeny
The price is ฿4,339
฿5,587 total
includes taxes & fees
3 Dec - 4 Dec
Lani Kai Beachfront Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Sanibel Isles

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Living area
The Anchor Inn
2.0 star property
10.0
Exceptional
85 reviews
View
A beach with a variety of seashells and pebbles.
Sanibel Island Beach Resort
3.0 star property
9.2
Wonderful
2,417 reviews
View
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
8.2
Very good
1,401 reviews
View
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.
Off the Charts Inn & Out Island Resort
2.5 star property
9.6
Exceptional
165 reviews
View
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.
Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.8
Excellent
1,003 reviews
View

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A street lined with palm trees and a sign for Periwinkle Place Shops.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

A beach with a variety of seashells and pebbles.
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island

10/10 Excellent

A really good looking resort. A great place to stay - directly on the beach with a great coffee shop and burger restaurant that we used whilst we were there! Easy to find, all the staff were fabulous and nice to have a daily housekeeping service as the sand gets everywhere! Check-in was easy and managed to get a room a little early which helped us get more time on the beach and in the hammocks.
United Kingdom
Steven
Reviewed February 3, 2026
Sanibel Island Beach Resort

Frequently Asked Questions

What's it like in Sanibel Isles?

Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.

How many hotels should I expect to find in the Sanibel Isles area?

When you want to find places to stay in Sanibel, start by booking one of Expedia's 6 hotels and other accommodation options in Sanibel Isles.

If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.

What is there to do in this Sanibel neighbourhood?

Woodring Point, Woodring Beach and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Causeway Islands Beach are also worth a visit when you're out sightseeing in Sanibel.