A sandy beach with a lighthouse and a house surrounded by trees.

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Check prices for these dates

This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Sanibel Isles hotels

A beach with a variety of seashells and pebbles.

1. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (2,316 reviews)
"We had a great time, location was perfect"
United States
Jill
The price is ฿5,929
฿7,534 total
includes taxes & fees
5 Oct - 6 Oct
Sanibel Island Beach Resort
A pathway leading to a pool area with lounge chairs and umbrellas, surrounded by tropical plants and a thatched-roof structure.

2. Sanibel Inn

Sanibel Inn
3.0 star property
East End, 3.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,004 reviews)
"Property was clean and very friendly staff food and bar on property and restaurant amazing stay"
United States
William
The price is ฿10,042
฿13,302 total
includes taxes & fees
28 Sept - 29 Sept
Sanibel Inn
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

3. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
5.2 km from Sanibel Isles
8.6 out of 10, Excellent, (1,003 reviews)
"Very clean resort; nice that beach chairs and umbrella available; good location"
United States
Charles
The price is ฿7,393
฿9,402 total
includes taxes & fees
7 Oct - 8 Oct
Marriott Sanibel Harbour Resort & Spa

4. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
9.8 out of 10, Exceptional, (72 reviews)
"10/10would stay here again"
United States
Jamie
The price is ฿4,889
฿5,948 total
includes taxes & fees
27 Sept - 28 Sept
The Anchor Inn
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

5. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is ฿2,848
฿3,176 total
includes taxes & fees
27 Sept - 28 Sept
Residence Inn by Marriott Fort Myers Sanibel
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

6. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
15.5 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,667 reviews)
"great hotel"
United States
john
The price is ฿3,411
฿3,804 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

7. Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3.5 km from Sanibel Isles
8.6 out of 10, Excellent, (2,701 reviews)
"Love the resort and great access to beach"
United States
Lisa Renee
The price is ฿11,273
฿14,756 total
includes taxes & fees
24 Sept - 25 Sept
Sundial Beach Resort & Spa
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

8. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 4.7 km from Sanibel Isles
8.8 out of 10, Excellent, (432 reviews)
"Loved the large, condo-size rooms. Loved our ocean view and wait staff at pool was great. I would definitely stay there again."
United States
Karen Elizabeth
The price is ฿8,421
฿9,389 total
includes taxes & fees
27 Sept - 28 Sept
Casa Ybel Resort
A pathway flanked by palm trees and wooden buildings with thatched roofs.

9. Kona Kai Motel

Kona Kai Motel
2.5 star property
Mid Island, 2.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,001 reviews)
"Good location"
United States
Presley
The price is ฿5,336
฿6,128 total
includes taxes & fees
28 Sept - 29 Sept
Kona Kai Motel
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

10. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 km from Sanibel Isles
8.2 out of 10, Very good, (1,356 reviews)
"Perfect stay"
United States
Jorge
The price is ฿2,358
฿2,629 total
includes taxes & fees
30 Sept - 1 Oct
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A wooden boardwalk leading to a beach with clear skies and calm waters.

11. Shalimar Beach Resort

Shalimar Beach Resort
3.5 star property
West End, 5.6 km from Sanibel Isles
9.8 out of 10, Exceptional, (98 reviews)
"This hotel was absolutely wonderful. I will book here again."
United States
PATRICIA
The price is ฿7,415
฿8,268 total
includes taxes & fees
27 Sept - 28 Sept
Shalimar Beach Resort
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

12. THE Palmview AND Sandpiper Inns

THE Palmview AND Sandpiper Inns
3.5 star property
Mid Island, 2.9 km from Sanibel Isles
9.2 out of 10, Wonderful, (225 reviews)
"Quaint beautiful place we enjoyed our stay very much"
United States
JACQUELINE
The price is ฿4,869
฿7,275 total
includes taxes & fees
12 Oct - 13 Oct
THE Palmview AND Sandpiper Inns
A beach with a view of the ocean and a sunset.

13. Island Inn

Island Inn
3.5 star property
West End, 5.9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,156 reviews)
"Great location"
United States
Nicole
The price is ฿6,698
฿7,468 total
includes taxes & fees
29 Sept - 30 Sept
Island Inn
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

14. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
12 km from Sanibel Isles
8.8 out of 10, Excellent, (1,011 reviews)
"This was close to our destination and always clean and friendly folks."
United States
Brandon
The price is ฿2,562
฿2,857 total
includes taxes & fees
29 Sept - 30 Sept
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

15. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,445 reviews)
"Great place"
United States
don
The price is ฿7,010
฿9,995 total
includes taxes & fees
30 Sept - 1 Oct
Pink Shell Beach Resort and Marina
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

16. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
12.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,003 reviews)
"Very clean and comfortable hotel! Great breakfast too!"
United States
Gigette
The price is ฿3,147
฿3,508 total
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

17. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,000 reviews)
"Perfect hotel"
United States
Ana
The price is ฿2,605
฿2,905 total
includes taxes & fees
24 Sept - 25 Sept
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

18. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
9.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,007 reviews)
"Very nice place for short stay. If you like a quiet environment, this is your best choice."
United States
selma
The price is ฿6,591
฿7,349 total
includes taxes & fees
24 Sept - 25 Sept
Best Western Plus Beach Resort
A hotel with a covered entrance, palm trees, and a well-maintained garden.

19. Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
21 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,007 reviews)
"Well maintained and clean place, the staff is friendly, good breakfast… overall great service"
United States
Iris
The price is ฿3,407
฿3,799 total
includes taxes & fees
29 Sept - 30 Sept
Homewood Suites by Hilton - Fort Myers
A balcony with a wicker sofa, a yellow table, and a potted plant.

20. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
10.8 km from Sanibel Isles
8.6 out of 10, Excellent, (1,002 reviews)
"Definitely would stay again"
United States
Sebastian
The price is ฿3,229
฿3,601 total
includes taxes & fees
24 Sept - 25 Sept
Latitude 26 Waterfront Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

A coastal scene with a lighthouse, beach, and ocean.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A street lined with palm trees and a sign for Periwinkle Place Shops.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

A beach with clear turquoise water, a sandy shore, and a weathered driftwood structure.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

Top Sanibel Isles Hotel Reviews

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

8/10 Good
"My stay was pleasant. Staff were friendly and polite. I would stay again."
Marnekia 2-night trip
Posted 2 hours ago
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Woodring Point, Woodring Beach and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Causeway Islands Beach are also worth a visit when you're out sightseeing in Sanibel.