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27 Dec - 28 Dec
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Our top choices for San Marco hotels

Daily cooked-to-order breakfast for a fee
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank
3.0 star property
San Marco
8.4 out of 10, Very good, (1004)
"The hotel es very nice & very well located near the San Marco arear. "
United States
Julio
The price is ฿3,322
฿3,770 total
includes taxes & fees
31 Dec - 1 Jan 2026
Hilton Garden Inn Jacksonville Downtown Southbank
Exterior
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank
3.0 star property
San Marco
8.6 out of 10, Excellent, (765)
"Clean hot tub and overall nice and up kept hotel"
United States
Cameron
The price is ฿4,046
฿4,593 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Jacksonville Downtown-Southbank
Restaurant
Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown
2.5 star property
San Marco
5.2 out of 10, (1000)
"Was a nice stay!"
United States
Allison
The price is ฿1,490
฿1,691 total
includes taxes & fees
28 Dec - 29 Dec
Scottish Inn Jacksonville Downtown
Outdoor pool
Magnuson Hotel Jacksonville Downtown

Magnuson Hotel Jacksonville Downtown

Magnuson Hotel Jacksonville Downtown
2.0 star property
San Marco
5.6 out of 10, (767)
"This is one of the need a room kinda places, very old, but was very clean."
Canada
Kevin
The price is ฿1,674
฿1,901 total
includes taxes & fees
28 Dec - 29 Dec
Magnuson Hotel Jacksonville Downtown
Free daily continental breakfast
TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg
2.5 star property
27.3 km from San Marco
10.0 out of 10, Exceptional, (28)
"Friendly staff Clean room Nice workout room Great breakfast"
United States
Robin
The price is ฿3,848
฿4,329 total
includes taxes & fees
4 Jan - 5 Jan 2026
TownePlace Suites by Marriott Middleburg
Restaurant
Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
Northside, 20.8 km from San Marco
8.8 out of 10, Excellent, (136)
"Will stay here again "
United States
Jose
The price is ฿2,234
฿2,536 total
includes taxes & fees
6 Jan - 7 Jan 2026
Extended Stay America Premier Suites - Jacksonville - Airport
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 12.7 km from San Marco
9.2 out of 10, Wonderful, (1004)
"Great stay and great customer service"
United States
Rebecca
The price is ฿2,881
฿3,270 total
includes taxes & fees
28 Dec - 29 Dec
Sheraton Jacksonville Hotel
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
25.1 km from San Marco
9.0 out of 10, Wonderful, (3435)
"Nice stay!"
United States
Mark
The price is ฿4,162
฿4,724 total
includes taxes & fees
30 Dec - 31 Dec
Margaritaville Jacksonville Beach
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
28.1 km from San Marco
9.0 out of 10, Wonderful, (1001)
"Friendly staff, easy check-in super clean room and facility. Location is excellent as well."
United States
Anthony
The price is ฿3,561
฿3,970 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 12.9 km from San Marco
9.2 out of 10, Wonderful, (1003)
"Quiet, near a lot of restaurants and shopping and all within walking distance. Staff was very friendly."
United States
Amber
The price is ฿3,824
฿4,340 total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Place Jacksonville / St. Johns Town Center
Exterior
Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
Northside, 14.7 km from San Marco
8.6 out of 10, Excellent, (1001)
"Clean room and very friendly and helpful staff at this location.. we will definitely stay here again"
United States
Judy
The price is ฿2,855
฿3,241 total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express Jacksonville - Blount Island by IHG
Premium bedding, down duvets, desk, laptop workspace
SpringHill Suites by Marriott Jacksonville Baymeadows

SpringHill Suites by Marriott Jacksonville Baymeadows

SpringHill Suites by Marriott Jacksonville Baymeadows
3.0 star property
Baymeadows, 12.5 km from San Marco
9.0 out of 10, Wonderful, (833)
"Very nice staff, clean, new bathrooms, excellent options at breakfast and great coffee. I would definitely stay here again "
United States
Candace
The price is ฿3,010
฿3,417 total
includes taxes & fees
8 Jan - 9 Jan 2026
SpringHill Suites by Marriott Jacksonville Baymeadows
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
25 km from San Marco
9.0 out of 10, Wonderful, (1002)
"Good location for exploring Ponte Vedra and Jacksonville Beach areas."
United States
Julianne
The price is ฿3,785
฿4,296 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Outdoor pool
Tru by Hilton Jacksonville West I 295

Tru by Hilton Jacksonville West I 295

Tru by Hilton Jacksonville West I 295
3.0 star property
Northwest, 12.8 km from San Marco
9.0 out of 10, Wonderful, (206)
"Súper clean hotel, very helpful staff"
United States
Otto
The price is ฿3,207
฿3,639 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Jacksonville West I 295
Exterior
Microtel Inn & Suites by Wyndham Jacksonville Airport

Microtel Inn & Suites by Wyndham Jacksonville Airport

Microtel Inn & Suites by Wyndham Jacksonville Airport
2.5 star property
Northside, 19.8 km from San Marco
7.8 out of 10, Good, (1219)
"Service was good although I feel the rooms could get a little makeover and colors "
United States
Dora
The price is ฿2,265
฿2,571 total
includes taxes & fees
1 Jan - 2 Jan 2026
Microtel Inn & Suites by Wyndham Jacksonville Airport
Lobby
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
20.7 km from San Marco
9.4 out of 10, Exceptional, (82)
"Great place to stay"
United States
Judy
The price is ฿4,551
฿5,165 total
includes taxes & fees
30 Dec - 31 Dec
Hilton Jacksonville At Mayo Clinic
Daily buffet breakfast (USD 26.95 per person)
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 2.1 km from San Marco
9.0 out of 10, Wonderful, (1401)
"Great stay "
United States
terria
The price is ฿4,966
฿5,692 total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Regency Jacksonville
Bar (on property)
Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
3.1 km from San Marco
9.2 out of 10, Wonderful, (269)
"The place was easy to get to, the build your own breakfast sandwich station was fantastic. "
United States
Patrick
The price is ฿4,046
฿4,593 total
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites By Hilton Jacksonville Downtown
Interior entrance
Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG
2.5 star property
21.1 km from San Marco
9.4 out of 10, Exceptional, (1175)
" Was great for last minute, simple 1 night stay! "
United States
Ashley
The price is ฿3,041
฿3,452 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Jacksonville South Bartram Prk by IHG
Lobby
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
Northside, 19.4 km from San Marco
9.0 out of 10, Wonderful, (2298)
"Nice and clean hotel, good breakfast, had a comfortable stay."
United States
Krishna
The price is ฿3,414
฿3,875 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hyatt Place Jacksonville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Marco

Find the best San Marco areas for the activities you enjoy most. Learn more about San Marco
Learn more about San Marco
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Cummer Museum of Art and Gardens featuring art and interior views as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

While visiting Northwest, you might make a stop by sights like Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail.

Top San Marco Hotel Reviews

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

10/10 Excellent
"Yes !! Beautiful room , staff was amazing!! But the shower only got warm for a minute then cold again ! Totally frustrating "
Timothy 1-night trip
Posted 2 days ago
Margaritaville Jacksonville Beach

Frequently asked questions

What is San Marco like?
San Marco is a neighbourhood that travellers like for its bars and restaurants. Consider a visit to Theatre Jacksonville as part of your San Marco travel plans.
Where is the best place to stay in San Marco?
Based on Expedia customer reviews, Hilton Garden Inn Jacksonville Downtown Southbank is the highest ranked property in San Marco. This hotel offers a restaurant and an outdoor pool. Other top choices in the neighbourhood include Homewood Suites by Hilton Jacksonville Downtown-Southbank and Magnuson Hotel Jacksonville Downtown.
How many hotels should I expect to find in the San Marco area?
If you're searching for places to stay in Jacksonville, Expedia has something to meet your needs with 86 San Marco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Marco, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within 24 hours of booking. Add your dates and click on "Search", then filter by "fully refundable" to review top deals in San Marco.
What is there to do in this Jacksonville neighbourhood?
Theatre Jacksonville is an attraction you might want to check out while you're in San Marco. When you're sightseeing in Jacksonville, Jacksonville Historical Center and Alexander Brest Planetarium are also worth a stop.

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