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Check prices for these dates

Tonight
5 Mar - 6 Mar
Tomorrow
6 Mar - 7 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for Saint Francis Healthcare System hotels

Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
0.9 km from Saint Francis Healthcare System
7.2 out of 10, Good, (706 reviews)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is ฿1,905
฿2,149 total
includes taxes & fees
11 Mar - 12 Mar
Quality Inn Cape Girardeau North
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
3.1 km from Saint Francis Healthcare System
9.6 out of 10, Exceptional, (1,013 reviews)
"Great place "
United States
Kelly
The price is ฿3,159
฿3,563 total
includes taxes & fees
10 Mar - 11 Mar
Drury Plaza Hotel Cape Girardeau Conference Center
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
3 km from Saint Francis Healthcare System
9.6 out of 10, Exceptional, (113 reviews)
"It was a nice stay"
United States
Douglas
The price is ฿3,082
฿3,508 total
includes taxes & fees
11 Mar - 12 Mar
Tru By Hilton Cape Girardeau
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
2.7 km from Saint Francis Healthcare System
6.0 out of 10, (211 reviews)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is ฿2,211
฿2,583 total
includes taxes & fees
6 Mar - 7 Mar
Town House Inn Cape Giradreau
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
3.6 km from Saint Francis Healthcare System
9.4 out of 10, Exceptional, (1,004 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ฿3,001
฿3,385 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
3.6 km from Saint Francis Healthcare System
9.4 out of 10, Exceptional, (1,006 reviews)
"Awesome stay!"
United States
Breckin
The price is ฿2,843
฿3,207 total
includes taxes & fees
10 Mar - 11 Mar
Drury Inn & Suites Cape Girardeau
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
3.7 km from Saint Francis Healthcare System
9.6 out of 10, Exceptional, (795 reviews)
"Excellent stay"
United States
Christina
The price is ฿3,341
฿3,770 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn Cape Girardeau I 55 East
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
3.7 km from Saint Francis Healthcare System
9.0 out of 10, Wonderful, (1,006 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ฿2,274
฿2,565 total
includes taxes & fees
10 Mar - 11 Mar
Pear Tree Inn Cape Girardeau West
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
4.1 km from Saint Francis Healthcare System
10.0 out of 10, Exceptional, (20 reviews)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is ฿4,747
฿5,355 total
includes taxes & fees
12 Mar - 13 Mar
Rockwood Inn
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
4.2 km from Saint Francis Healthcare System
9.0 out of 10, Wonderful, (718 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is ฿2,658
฿2,877 total
includes taxes & fees
8 Mar - 9 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
4.7 km from Saint Francis Healthcare System
9.4 out of 10, Exceptional, (162 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
The price is ฿3,195
฿3,605 total
includes taxes & fees
19 Mar - 20 Mar
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
4.2 km from Saint Francis Healthcare System
8.2 out of 10, Very good, (748 reviews)
"Clean and comfortable every time. This is a “go to” hotel "
United States
Jacqulyn
The price is ฿2,911
฿3,150 total
includes taxes & fees
8 Mar - 9 Mar
Comfort Suites Jackson-Cape Girardeau
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
5.3 km from Saint Francis Healthcare System
9.6 out of 10, Exceptional, (490 reviews)
"Very nice hotel!"
United States
Angie
The price is ฿3,949
฿4,474 total
includes taxes & fees
14 Mar - 15 Mar
Courtyard by Marriott Cape Girardeau Downtown
Lobby sitting area

The Riverview

The Riverview
4.0 star property
5.3 km from Saint Francis Healthcare System
9.4 out of 10, Exceptional, (516 reviews)
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is ฿3,042
฿3,432 total
includes taxes & fees
8 Mar - 9 Mar
The Riverview
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
4.9 km from Saint Francis Healthcare System
8.2 out of 10, Very good, (900 reviews)
"Room was clean and spacious."
United States
George
The price is ฿2,496
฿2,989 total
includes taxes & fees
8 Mar - 9 Mar
Candlewood Suites Cape Girardeau by IHG
Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
12.3 km from Saint Francis Healthcare System
9.6 out of 10, Exceptional, (1,008 reviews)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is ฿2,527
฿2,671 total
includes taxes & fees
9 Mar - 10 Mar
Drury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Saint Francis Healthcare System Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"My favorite place tpstay when in the area."
Jack 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

Hotels near other Saint Francis Healthcare System attractions

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Cape Splash Family Aquatic Center

Bring the children to Cape Splash Family Aquatic Center and have a fun-filled day at this theme park in Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
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Frequently asked questions

What's the area like around Saint Francis Healthcare System?
Saint Francis Healthcare System is located in Cape Girardeau. This family-friendly area is known for its array of dining options. You'll find 56 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to Saint Francis Healthcare System?
Quality Inn Cape Girardeau North is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.6 mi (0.9 km) from Saint Francis Healthcare System. Other good options within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Drury Inn & Suites Cape Girardeau.
How many hotels are there near Saint Francis Healthcare System?
Expedia has 56 hotels and other accommodation options a few miles from Saint Francis Healthcare System.
If I need to cancel the hotel reservation for my stay near Saint Francis Healthcare System, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best options available near Saint Francis Healthcare System.
What can I see and do near Saint Francis Healthcare System?
You might spend a leisurely day outdoors at Cape Rock Park and Fort D Historic Site. Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center and Lazy L Safari Park are fun stops for the whole family while you're in town. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.