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12 Oct - 13 Oct
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Top Trending Hotels Near Mississippi River

River's Edge Motel
Balcony

River's Edge Motel

2.0 star property
9.0 out of 10, Wonderful, (347)
"Clean,quiet, easy parking and great view of the river."
The price is ฿2,615
฿2,969 total
includes taxes & fees
13 Oct - 14 Oct
River's Edge Motel
The Eagles Nest Inn
Interior

The Eagles Nest Inn

3.0 star property
9.6 out of 10, Exceptional, (15)
"The room was great. Large and attractive!! Nice bathroom. Had all the convenience you need from TV to mini frig. "
The price is ฿3,237
฿3,675 total
includes taxes & fees
21 Oct - 22 Oct
The Eagles Nest Inn
Baymont by Wyndham Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (713)
"It was definitely a nice place. Kinda odd that you could only be on the 1st floor. Pool area was nice and huge. But hardly anyone stayed here. "
The price is ฿2,060
฿2,381 total
includes taxes & fees
13 Oct - 14 Oct
Baymont by Wyndham Hannibal
Riverside Inn Hannibal
55-inch TV with cable channels, Netflix, Hulu

Riverside Inn Hannibal

2.5 star property
9.4 out of 10, Exceptional, (152)
"Very nice rooms right on the river!"
The price is ฿4,523
฿6,322 total
includes taxes & fees
20 Oct - 21 Oct
Riverside Inn Hannibal
Best Western On The River
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1017)
"Clean room and great breakfast."
The price is ฿3,596
฿4,130 total
includes taxes & fees
2 Nov - 3 Nov
Best Western On The River
Sleep Inn & Suites
Exterior

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1004)
"great stay!"
The price is ฿3,501
฿4,056 total
includes taxes & fees
2 Nov - 3 Nov
Sleep Inn & Suites
Lighthouse Inn & Suites
Deluxe Room | 1 bedroom, down duvets, blackout curtains, iron/ironing board

Lighthouse Inn & Suites

4.0 star property
8.8 out of 10, Excellent, (21)
"Very nice room, close enough to walk to riverfront attractions. "
The price is ฿5,520
฿6,340 total
includes taxes & fees
13 Oct - 14 Oct
Lighthouse Inn & Suites
Motel 6 Hannibal, MO
Lobby sitting area

Motel 6 Hannibal, MO

2.0 star property
7.4 out of 10, Good, (1006)
"Very clean rooms and staff is very friendly "
The price is ฿1,798
฿2,065 total
includes taxes & fees
19 Oct - 20 Oct
Motel 6 Hannibal, MO
Garden House Bed and Breakfast
Front of property

Garden House Bed and Breakfast

2.0 star property
8.6 out of 10, Excellent, (27)
"A beautiful 19th century mansion, decorated in period. Quiet and comfortable."
The price is ฿3,307
฿3,798 total
includes taxes & fees
13 Oct - 14 Oct
Garden House Bed and Breakfast
Comfort Inn & Suites - Hannibal
Indoor pool, pool loungers

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (639)
"The beds were super comfy"
The price is ฿2,913
฿3,443 total
includes taxes & fees
2 Nov - 3 Nov
Comfort Inn & Suites - Hannibal
Super 8 by Wyndham Hannibal
Exterior

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1000)
"Wonderful staff"
The price is ฿1,973
฿2,266 total
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets

Days Inn by Wyndham Hannibal

2.0 star property
7.4 out of 10, Good, (206)
"very average but right off the highway, so was convenient."
The price is ฿2,168
฿2,490 total
includes taxes & fees
27 Oct - 28 Oct
Days Inn by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Lobby sitting area

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (138)
"Wonderful and friendly staff, an actual hot real breakfast selection! Clean pool and gaming area, would stay again!"
The price is ฿1,854
฿2,143 total
includes taxes & fees
2 Nov - 3 Nov
Howard Johnson BY Wyndham Hannibal
Economy Inn Wentzville
Lobby

Economy Inn Wentzville

2.0 star property
6.4 out of 10, (469)
"Really cozy place to stay at!"
The price is ฿1,962
฿2,225 total
includes taxes & fees
13 Oct - 14 Oct
Economy Inn Wentzville
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Standard Room, 2 Queen Beds | Desk, iron/ironing board, free WiFi, bed sheets

Super 8 by Wyndham O'Fallon MO/St. Louis Area

2.0 star property
6.8 out of 10, (977)
"Newly remodeled. "
The price is ฿2,195
฿2,589 total
includes taxes & fees
19 Oct - 20 Oct
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Quality Inn & Suites Hannibal
Lobby

Quality Inn & Suites Hannibal

2.5 star property
8.0 out of 10, Very good, (1005)
"Front desk was very nice"
The price is ฿2,860
฿3,285 total
includes taxes & fees
2 Nov - 3 Nov
Quality Inn & Suites Hannibal
Relax Inn Saint Charles
Lobby

Relax Inn Saint Charles

2.0 star property
6.6 out of 10, (1008)
"Good stay"
The price is ฿2,060
฿2,367 total
includes taxes & fees
13 Oct - 14 Oct
Relax Inn Saint Charles
Days Inn by Wyndham St Peters/St Charles
Lobby

Days Inn by Wyndham St Peters/St Charles

2.0 star property
6.4 out of 10, (994)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
The price is ฿2,195
฿2,523 total
includes taxes & fees
14 Oct - 15 Oct
Days Inn by Wyndham St Peters/St Charles
Baymont by Wyndham Keokuk
Lobby

Baymont by Wyndham Keokuk

2.5 star property
6.2 out of 10, (475)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
The price is ฿1,795
฿2,010 total
includes taxes & fees
9 Nov - 10 Nov
Baymont by Wyndham Keokuk
LAKEVIEWINN
Exterior

LAKEVIEWINN

2.5 star property
5.4 out of 10, (25)
"Great people but they in a middle of remodel so bare with them please"
The price is ฿2,648
฿2,991 total
includes taxes & fees
13 Oct - 14 Oct
LAKEVIEWINN
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi River Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Clean room and staff was great "
Beth 2-night trip
Posted 6 days ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hotels near other Mississippi River attractions

Mark Twain Cave

4.4/5 (128 reviews)
Explore the great outdoors at Mark Twain Cave, a lovely green space in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.
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Mark Twain Cave and Cameron Cave

4.5/5 (51 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave and Cameron Cave. While in this trendy area, you can savour the top-notch restaurants.
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Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. You'll find it 76 mi (122.3 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Airport and Drury Plaza Hotel St. Louis at the Arch.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.