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Our top choices for Mississippi River hotels

River's Edge Motel
River's Edge Motel13.6 km from Mississippi River
9.0 out of 10, Wonderful, (367 reviews)
The price is ฿2,619
฿2,973 total
includes taxes & fees
16 Jun - 17 Jun

The Eagles Nest Inn
The Eagles Nest Inn14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
The price is ฿3,478
฿3,949 total
includes taxes & fees
22 Jun - 23 Jun

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal26.3 km from Mississippi River
6.4 out of 10, (774 reviews)
The price is ฿2,062
฿2,395 total
includes taxes & fees
16 Jun - 17 Jun

Best Western On The River
Best Western On The River25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,016 reviews)
The price is ฿3,614
฿4,168 total
includes taxes & fees
28 Jun - 29 Jun

Riverside Inn Hannibal
Riverside Inn Hannibal25.1 km from Mississippi River
9.4 out of 10, Exceptional, (178 reviews)
The price is ฿5,271
฿7,213 total
includes taxes & fees
16 Jun - 17 Jun

Economy Inn Wentzville
Economy Inn Wentzville86.8 km from Mississippi River
6.4 out of 10, (546 reviews)
The price is ฿2,291
฿2,600 total
includes taxes & fees
16 Jun - 17 Jun

Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
The price is ฿4,012
฿4,667 total
includes taxes & fees
28 Jun - 29 Jun

Lighthouse Inn & Suites
Lighthouse Inn & Suites25.8 km from Mississippi River
9.0 out of 10, Wonderful, (30 reviews)
The price is ฿5,593
฿7,584 total
includes taxes & fees
16 Jun - 17 Jun

LAKEVIEWINN
LAKEVIEWINN89.4 km from Mississippi River
6.0 out of 10, (53 reviews)
The price is ฿2,210
฿2,496 total
includes taxes & fees
12 Jul - 13 Jul

Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles93.8 km from Mississippi River
6.2 out of 10, (1,005 reviews)
The price is ฿2,357
฿2,709 total
includes taxes & fees
21 Jun - 22 Jun

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO26.1 km from Mississippi River
7.4 out of 10, Good, (1,010 reviews)
The price is ฿1,767
฿2,038 total
includes taxes & fees
21 Jun - 22 Jun

Garden House Bed and Breakfast
Garden House Bed and Breakfast25.2 km from Mississippi River
8.4 out of 10, Very good, (43 reviews)
The price is ฿3,490
฿4,027 total
includes taxes & fees
19 Jun - 20 Jun

Baymont by Wyndham Keokuk
Baymont by Wyndham Keokuk96.1 km from Mississippi River
6.2 out of 10, (519 reviews)
The price is ฿2,416
฿2,706 total
includes taxes & fees
21 Jun - 22 Jun

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North
La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North109.6 km from Mississippi River
6.6 out of 10, (1,013 reviews)
The price is ฿2,337
฿2,857 total
includes taxes & fees
12 Jul - 13 Jul

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal26.2 km from Mississippi River
7.6 out of 10, Good, (705 reviews)
The price is ฿2,830
฿3,362 total
includes taxes & fees
12 Jul - 13 Jul

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal26.3 km from Mississippi River
7.2 out of 10, Good, (1,004 reviews)
The price is ฿2,177
฿2,511 total
includes taxes & fees
22 Jun - 23 Jun

Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West30 km from Mississippi River
8.0 out of 10, Very good, (1,012 reviews)
The price is ฿2,460
฿2,862 total
includes taxes & fees
12 Jul - 13 Jul

Sleep Inn Saint Charles North
Sleep Inn Saint Charles North97.1 km from Mississippi River
5.8 out of 10, (543 reviews)
The price is ฿2,615
฿3,005 total
includes taxes & fees
21 Jun - 22 Jun

Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal26.3 km from Mississippi River
7.4 out of 10, Good, (169 reviews)
The price is ฿2,021
฿2,348 total
includes taxes & fees
21 Jun - 22 Jun

Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal26.4 km from Mississippi River
7.4 out of 10, Good, (250 reviews)
The price is ฿2,151
฿2,481 total
includes taxes & fees
16 Jun - 17 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mississippi River
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() River's Edge Motel | 9.0 Wonderful 367 reviews | View | ||||||
![]() The Eagles Nest Inn | 9.4 Exceptional 25 reviews | View | ||||||
![]() Baymont by Wyndham Hannibal | 6.4 774 reviews | View | ||||||
![]() Best Western On The River | 8.6 Excellent 1,016 reviews | View | ||||||
![]() Riverside Inn Hannibal | 9.4 Exceptional 178 reviews | View |
Top Mississippi River Hotel Reviews

Clayton Plaza Hotel & Extended Stay
10/10 Excellent








































































