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Our top choices for Mississippi River hotels

River's Edge Motel
River's Edge Motel13.6 km from Mississippi River
9.0 out of 10, Wonderful, (359 reviews)
The price is ฿2,489
฿2,826 total
includes taxes & fees
21 Feb - 22 Feb

The Eagles Nest Inn
The Eagles Nest Inn14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
The price is ฿2,975
฿3,378 total
includes taxes & fees
19 Feb - 20 Feb

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal26.3 km from Mississippi River
6.4 out of 10, (741 reviews)
The price is ฿1,820
฿2,105 total
includes taxes & fees
22 Feb - 23 Feb

Best Western On The River
Best Western On The River25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
The price is ฿2,016
฿2,316 total
includes taxes & fees
19 Feb - 20 Feb

Riverside Inn Hannibal
Riverside Inn Hannibal25.1 km from Mississippi River
9.4 out of 10, Exceptional, (167 reviews)
The price is ฿4,427
฿6,157 total
includes taxes & fees
2 Mar - 3 Mar

Super 8 by Wyndham O'Fallon MO/St. Louis Area
Super 8 by Wyndham O'Fallon MO/St. Louis Area90.7 km from Mississippi River
6.8 out of 10, (1,000 reviews)
The price is ฿2,076
฿2,448 total
includes taxes & fees
26 Feb - 27 Feb

Economy Inn Wentzville
Economy Inn Wentzville86.8 km from Mississippi River
6.4 out of 10, (518 reviews)
The price is ฿1,867
฿2,118 total
includes taxes & fees
19 Feb - 20 Feb

Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
The price is ฿3,167
฿3,669 total
includes taxes & fees
15 Mar - 16 Mar

Relax Inn Saint Charles
Relax Inn Saint Charles98 km from Mississippi River
6.8 out of 10, (1,000 reviews)
The price is ฿1,960
฿2,253 total
includes taxes & fees
19 Feb - 20 Feb

Lighthouse Inn & Suites
Lighthouse Inn & Suites25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
The price is ฿5,255
฿7,107 total
includes taxes & fees
19 Feb - 20 Feb

Garden House Bed and Breakfast
Garden House Bed and Breakfast25.2 km from Mississippi River
8.6 out of 10, Excellent, (38 reviews)
The price is ฿3,018
฿3,466 total
includes taxes & fees
19 Feb - 20 Feb

Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
The price is ฿1,931
฿2,220 total
includes taxes & fees
22 Feb - 23 Feb

Baymont by Wyndham Keokuk
Baymont by Wyndham Keokuk96.1 km from Mississippi River
6.2 out of 10, (497 reviews)
The price is ฿1,860
฿2,083 total
includes taxes & fees
22 Feb - 23 Feb

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal26.2 km from Mississippi River
7.6 out of 10, Good, (673 reviews)
The price is ฿2,241
฿2,667 total
includes taxes & fees
27 Feb - 28 Feb

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North109.6 km from Mississippi River
6.6 out of 10, (1,003 reviews)
The price is ฿1,836
฿2,244 total
includes taxes & fees
1 Mar - 2 Mar

Holiday Inn Express & Suites Hannibal - Medical Center by IHG
Holiday Inn Express & Suites Hannibal - Medical Center by IHG30.7 km from Mississippi River
9.8 out of 10, Exceptional, (387 reviews)
The price is ฿3,857
฿4,430 total
includes taxes & fees
22 Feb - 23 Feb

LAKEVIEWINN
LAKEVIEWINN89.4 km from Mississippi River
5.6 out of 10, (34 reviews)
The price is ฿2,100
฿2,372 total
includes taxes & fees
22 Feb - 23 Feb

Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West30 km from Mississippi River
8.0 out of 10, Very good, (1,011 reviews)
The price is ฿2,165
฿2,508 total
includes taxes & fees
26 Feb - 27 Feb

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
The price is ฿1,711
฿1,965 total
includes taxes & fees
3 Mar - 4 Mar

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
The price is ฿1,784
฿2,049 total
includes taxes & fees
22 Feb - 23 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mississippi River
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() River's Edge Motel | 9.0 Wonderful 359 reviews | View | ||||||
![]() The Eagles Nest Inn | 9.4 Exceptional 21 reviews | View | ||||||
![]() Baymont by Wyndham Hannibal | 6.4 741 reviews | View | ||||||
![]() Best Western On The River | 8.6 Excellent 1,000 reviews | View | ||||||
![]() Riverside Inn Hannibal | 9.4 Exceptional 167 reviews | View |
Top Mississippi River Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District
10/10 Excellent








































































