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Our top choices for Lake Nona Medical City hotels

Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (400 reviews)
"Great hotel!"
United States
sammypsu
The price is ฿4,339
฿4,930 total
includes taxes & fees
5 Jul - 6 Jul
Aloft by Marriott Orlando Lake Nona

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (644 reviews)
"The rooms were spacious, clean and very comfortable."
United States
Floyd
The price is ฿4,639
฿5,271 total
includes taxes & fees
5 Jul - 6 Jul
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (339 reviews)
"Great staff on front desk."
United Kingdom
David
The price is ฿5,841
฿6,637 total
includes taxes & fees
26 Jul - 27 Jul
Residence Inn Orlando Lake Nona

Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks
3.0 star property
30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,589 reviews)
"Great stay highly recommend"
United States
Rebeca
The price is ฿797
฿2,381 total
includes taxes & fees
29 Jun - 30 Jun
Kompose Boutique Resort at Theme Parks

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel
3.0 star property
International Drive District, 21.3 km from Lake Nona Medical City
8.6 out of 10, Excellent, (1,698 reviews)
"Breakfast was great Clean room Good location"
Canada
Tracy
The price is ฿2,525
฿2,841 total
includes taxes & fees
19 Jul - 20 Jul
DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

Hyatt House Orlando International Drive

Hyatt House Orlando International Drive
4.0 star property
International Drive District, 20.2 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,961 reviews)
"Great place to stay"
United States
Idoel
The price is ฿3,875
฿4,359 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt House Orlando International Drive

Courtyard by Marriott across Universal Orlando

Courtyard by Marriott across Universal Orlando
3.0 star property
Florida Center, 21.6 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (182 reviews)
"Love staying there..will definitely be back."
Canada
hilary
The price is ฿3,471
฿3,905 total
includes taxes & fees
26 Jul - 27 Jul
Courtyard by Marriott across Universal Orlando

Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport
4.0 star property
7.7 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,248 reviews)
"great stay , convenient location"
United States
RICHARD
The price is ฿6,308
฿7,097 total
includes taxes & fees
29 Jun - 30 Jun
Hyatt Regency Orlando International Airport

Vacation Village Orlando, Celebration

Vacation Village Orlando, Celebration
3.0 star property
25.4 km from Lake Nona Medical City
8.6 out of 10, Excellent, (4,397 reviews)
"Great stay"
United States
Martena
The price is ฿2,354
฿3,506 total
includes taxes & fees
30 Jun - 1 Jul
Vacation Village Orlando, Celebration

La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (2,216 reviews)
"great price for the stay and location"
United States
Robert
The price is ฿2,466
฿2,774 total
includes taxes & fees
30 Jun - 1 Jul
La Quinta Inn & Suites by Wyndham Orlando Airport

Margaritaville Resort Orlando with H2O Waterpark

Margaritaville Resort Orlando with H2O Waterpark
4.0 star property
32.8 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,614 reviews)
"Such a beautiful resort to be at."
United States
tammy
The price is ฿5,377
฿7,921 total
includes taxes & fees
13 Jul - 14 Jul
Margaritaville Resort Orlando with H2O Waterpark

Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,742 reviews)
The price is ฿3,255
฿3,662 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn & Suites Orlando Airport @ Gateway Village

DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport
4.0 star property
Airport North, 11.2 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2,447 reviews)
"Airport shuttle and location were great!"
United States
Kimberly
The price is ฿2,756
฿3,100 total
includes taxes & fees
12 Jul - 13 Jul
DoubleTree by Hilton Orlando Airport

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (4,968 reviews)
"Always love staying there"
United States
John
The price is ฿3,977
฿4,474 total
includes taxes & fees
5 Jul - 6 Jul
Rosen Shingle Creek

EVEN Hotel Orlando International Airport by IHG

EVEN Hotel Orlando International Airport by IHG
3.5 star property
Airport North, 11.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (582 reviews)
"Great location!"
United States
Mark
The price is ฿3,104
฿3,492 total
includes taxes & fees
20 Jul - 21 Jul
EVEN Hotel Orlando International Airport by IHG

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,941 reviews)
"Nice place to stay"
United States
LaToya
The price is ฿3,875
฿4,359 total
includes taxes & fees
30 Jun - 1 Jul
Hyatt House Orlando Airport

Fairfield Inn By Marriott Orlando Airport

Fairfield Inn By Marriott Orlando Airport
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,507 reviews)
"Friendly staff, breakfast was excellent!"
Canada
Roger
The price is ฿2,667
฿3,000 total
includes taxes & fees
20 Jul - 21 Jul
Fairfield Inn By Marriott Orlando Airport

Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1,906 reviews)
"The room was very spacious and clean! Great location by airport!"
United States
Hector
The price is ฿3,092
฿3,479 total
includes taxes & fees
20 Jul - 21 Jul
Cambria Hotel Orlando Airport

Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL
3.0 star property
Airport North, 11 km from Lake Nona Medical City
8.0 out of 10, Very good, (4,655 reviews)
"Clean rooms and great breakfast"
United States
Rebecca
The price is ฿2,667
฿3,000 total
includes taxes & fees
21 Jul - 22 Jul
Country Inn & Suites by Radisson, Orlando Airport, FL

Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,046 reviews)
"Good hotel near the airport"
United States
Brandon
The price is ฿2,670
฿3,004 total
includes taxes & fees
28 Jun - 29 Jun
Wyndham Garden Orlando Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.