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13 Oct - 14 Oct
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Top Trending Hotels Near Lake Nona Medical City, Orlando

Aloft Orlando Lake Nona
Lounge
Aloft Orlando Lake Nona
3.0 star property
9.6 out of 10, Exceptional, (229)
"Fun hotel with clean rooms , nice restaurants"
The price is ฿4,528
฿5,094 total
includes taxes & fees
29 Oct - 30 Oct
Aloft Orlando Lake Nona
Courtyard Orlando Lake Nona
Outdoor pool
Courtyard Orlando Lake Nona
3.0 star property
9.6 out of 10, Exceptional, (577)
"Great stay"
The price is ฿5,263
฿5,981 total
includes taxes & fees
26 Oct - 27 Oct
Courtyard Orlando Lake Nona
Residence Inn Orlando Lake Nona
Outdoor pool
Residence Inn Orlando Lake Nona
3.0 star property
9.6 out of 10, Exceptional, (323)
"Good hotel "
The price is ฿5,852
฿6,649 total
includes taxes & fees
26 Oct - 27 Oct
Residence Inn Orlando Lake Nona
La Quinta Inn & Suites by Wyndham Orlando UCF
Lobby
La Quinta Inn & Suites by Wyndham Orlando UCF
3.0 star property
8.6 out of 10, Excellent, (2684)
"This hotel was a nice inexpensive place to stay for the night. Very clean, and the staff was great. "
The price is ฿3,157
฿3,551 total
includes taxes & fees
21 Oct - 22 Oct
La Quinta Inn & Suites by Wyndham Orlando UCF
Ramada by Wyndham Suites Orlando Airport
Premium bedding, in-room safe, desk, blackout curtains
Ramada by Wyndham Suites Orlando Airport
3.0 star property
8.2 out of 10, Very good, (4977)
"Very nice stay"
The price is ฿2,584
฿2,907 total
includes taxes & fees
28 Oct - 29 Oct
Ramada by Wyndham Suites Orlando Airport
The Delaney Hotel
Terrace/patio
The Delaney Hotel
3.5 star property
9.6 out of 10, Exceptional, (1019)
"great restaurant and even better rooms!"
The Delaney Hotel
Wingate by Wyndham - Orlando International Airport
Pillow-top beds, in-room safe, desk, blackout curtains
Wingate by Wyndham - Orlando International Airport
3.0 star property
8.8 out of 10, Excellent, (3650)
"Great hotel"
The price is ฿2,630
฿2,959 total
includes taxes & fees
21 Oct - 22 Oct
Wingate by Wyndham - Orlando International Airport
Country Inn & Suites by Radisson, Orlando Airport, FL
Exterior
Country Inn & Suites by Radisson, Orlando Airport, FL
3.0 star property
7.8 out of 10, Good, (4084)
"Clean room great beds and pillows and great breakfast"
The price is ฿1,991
฿2,239 total
includes taxes & fees
29 Oct - 30 Oct
Country Inn & Suites by Radisson, Orlando Airport, FL
La Quinta Inn & Suites by Wyndham Orlando Airport North
Dining
La Quinta Inn & Suites by Wyndham Orlando Airport North
3.0 star property
7.4 out of 10, Good, (471)
"Clean room close to airport and many good restaurants "
The price is ฿2,215
฿2,492 total
includes taxes & fees
29 Oct - 30 Oct
La Quinta Inn & Suites by Wyndham Orlando Airport North
Wyndham Garden Orlando Airport
Outdoor pool, pool loungers
Wyndham Garden Orlando Airport
3.0 star property
9.0 out of 10, Wonderful, (3870)
"Clean rooms so peaceful and staff are very professional and friendly "
The price is ฿2,929
฿3,295 total
includes taxes & fees
20 Oct - 21 Oct
Wyndham Garden Orlando Airport
Ramada by Wyndham Hotel & Water Park
Water park
Ramada by Wyndham Hotel & Water Park
3.0 star property
7.2 out of 10, Good, (1499)
"Excellent staff and service "
The price is ฿1,042
฿2,108 total
includes taxes & fees
22 Oct - 23 Oct
Ramada by Wyndham Hotel & Water Park
SPOT X Hotel Orlando/Intl Dr by The Red Collection
Front of property – evening/night
SPOT X Hotel Orlando/Intl Dr by The Red Collection
3.0 star property
8.6 out of 10, Excellent, (2803)
"renovated rooms, nice staff"
The price is ฿1,953
฿2,783 total
includes taxes & fees
29 Oct - 30 Oct
SPOT X Hotel Orlando/Intl Dr by The Red Collection
The Eo Inn - Downtown
Front of property
The Eo Inn - Downtown
3.0 star property
8.0 out of 10, Very good, (1007)
"I loved this hotel. The staff was very down to earth "
The price is ฿3,923
฿4,413 total
includes taxes & fees
15 Oct - 16 Oct
The Eo Inn - Downtown
Lake Nona Wave Hotel
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers
Lake Nona Wave Hotel
4.0 star property
9.6 out of 10, Exceptional, (1011)
"The rooms are amazing, clean well stocked. The staff is very friendly. We ate dinner at the Garni Cafe. The food was great, we also had breakfast there and that was also very good."
The price is ฿8,312
฿9,434 total
includes taxes & fees
31 Oct - 1 Nov
Lake Nona Wave Hotel
Orlando Palms Hotel
Outdoor pool, open 9 AM to 10 PM, pool loungers
Orlando Palms Hotel
2.5 star property
7.6 out of 10, Good, (2133)
"Great stay!!!"
Orlando Palms Hotel
DoubleTree by Hilton at the Entrance to Universal Orlando
Outdoor pool
DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
8.4 out of 10, Very good, (6758)
"Great stay"
The price is ฿2,654
฿2,986 total
includes taxes & fees
3 Nov - 4 Nov
DoubleTree by Hilton at the Entrance to Universal Orlando
Kompose Boutique Resort at Theme Parks
Suite, 1 King Bed with Sofa bed, Balcony | 1 bedroom, premium bedding, minibar, in-room safe
Kompose Boutique Resort at Theme Parks
3.0 star property
9.4 out of 10, Exceptional, (1525)
"Great price, convenient and lovely surroundings. "
The price is ฿1,879
฿2,525 total
includes taxes & fees
15 Oct - 16 Oct
Kompose Boutique Resort at Theme Parks
Hyatt Regency Orlando
2 outdoor pools, pool cabanas (surcharge), pool umbrellas
Hyatt Regency Orlando
4.5 star property
9.2 out of 10, Wonderful, (1770)
"Great place to stay "
The price is ฿4,879
฿7,309 total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Regency Orlando
Hyatt Regency Orlando International Airport
Terrace/patio
Hyatt Regency Orlando International Airport
4.0 star property
9.4 out of 10, Exceptional, (3661)
"This hotel is amazing we loved it all around "
The price is ฿5,885
฿6,620 total
includes taxes & fees
20 Oct - 21 Oct
Hyatt Regency Orlando International Airport
Tru By Hilton Orlando Convention Center Area, FL
Exterior
Tru By Hilton Orlando Convention Center Area, FL
3.5 star property
9.0 out of 10, Wonderful, (3434)
"Great stay with activities for the whole family"
The price is ฿2,654
฿2,986 total
includes taxes & fees
26 Oct - 27 Oct
Tru By Hilton Orlando Convention Center Area, FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Magic Kingdom® Theme Park showing interior views and rides as well as a couple
Photo by ©Disney
Open Photo by ©Disney

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Universal Studios Florida® featuring night scenes, a city and signage

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Downtown Orlando

One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Top Lake Nona Medical City Hotel Reviews

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

10/10 Excellent
"Clean room"
Terrance Antonio 3-night trip
Posted 12 hours ago
Universal's Cabana Bay Beach Resort

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Places you might want to visit in the area around Lake Nona Medical City include Eagle Creek Golf Club and Austin-Tindall Regional Park. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.