Search Hotels in Lake Nona Medical City, Orlando

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Our top choices for Lake Nona Medical City hotels

Aloft Orlando Lake Nona

Aloft Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (300 reviews)
"Our stay was great!"
United States
Kendra
The price is ฿5,322
฿5,987 total
includes taxes & fees
8 Feb - 9 Feb
Aloft Orlando Lake Nona

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.4 out of 10, Exceptional, (605 reviews)
"Clean room and pleasant staff"
United States
Michelle
The price is ฿5,291
฿6,012 total
includes taxes & fees
8 Feb - 9 Feb
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (327 reviews)
"Very clean hotel and spacious room with comfortable seating and kitchen area. The location was great for me as I was there visiting someone in an area hospital. There are also restaurants and coffee shops right outside the entrance. "
United States
Sharon
The price is ฿5,886
฿6,688 total
includes taxes & fees
8 Feb - 9 Feb
Residence Inn Orlando Lake Nona

Caribe Royale Orlando

Caribe Royale Orlando
4.5 star property
21.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (4,633 reviews)
"Great Stay ! "
United States
Matthew
The price is ฿4,821
฿6,750 total
includes taxes & fees
23 Jan - 24 Jan
Caribe Royale Orlando

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort
3.5 star property
Florida Center, 22.2 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (6,123 reviews)
"Great location, close to parks, clean, friendly staff."
United States
Linda
The price is ฿4,164
฿4,684 total
includes taxes & fees
25 Jan - 26 Jan
Universal's Cabana Bay Beach Resort

Red Lion Hotel Orlando Lake Buena Vista South

Red Lion Hotel Orlando Lake Buena Vista South
3.5 star property
21.3 km from Lake Nona Medical City
8.8 out of 10, Excellent, (4,359 reviews)
"Stay here a few times a year, always great! Wouldn’t stay anywhere else. "
United States
Raymond
The price is ฿1,719
฿2,662 total
includes taxes & fees
25 Jan - 26 Jan
Red Lion Hotel Orlando Lake Buena Vista South

La Quinta by Wyndham Orlando Airport North - Free Airport Shuttle!

La Quinta by Wyndham Orlando Airport North - Free Airport Shuttle!
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (1,093 reviews)
"Hotel is very nice and staff very helpful."
United States
Angela
The price is ฿2,954
฿3,323 total
includes taxes & fees
9 Feb - 10 Feb
La Quinta by Wyndham Orlando Airport North - Free Airport Shuttle!

Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,790 reviews)
"Great service at airport, clean rooms and breakfast was good."
United States
tammy
The price is ฿3,673
฿4,132 total
includes taxes & fees
2 Feb - 3 Feb
Wingate by Wyndham - Orlando International Airport

Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.4 out of 10, Very good, (5,278 reviews)
"Great stay overall"
United States
Bibi
The price is ฿3,379
฿3,801 total
includes taxes & fees
27 Jan - 28 Jan
Ramada by Wyndham Suites Orlando Airport

Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,881 reviews)
"Great hotel."
Canada
Rory
The price is ฿3,965
฿4,461 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Express Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,100 reviews)
"Great quick stay for a good value!"
United States
Pamela
The price is ฿3,632
฿4,085 total
includes taxes & fees
26 Jan - 27 Jan
avid hotel Orlando International Airport by IHG

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
Florida Center, 21.7 km from Lake Nona Medical City
8.4 out of 10, Very good, (6,937 reviews)
"Great location, clean room, friendly staff"
United States
Joseph
The price is ฿3,218
฿3,620 total
includes taxes & fees
28 Jan - 29 Jan
DoubleTree by Hilton at the Entrance to Universal Orlando

Rosen Inn at Pointe Orlando

Rosen Inn at Pointe Orlando
3.0 star property
International Drive District, 20.7 km from Lake Nona Medical City
8.6 out of 10, Excellent, (5,593 reviews)
"Great stay"
United States
Stephanie
The price is ฿2,488
฿2,799 total
includes taxes & fees
27 Jan - 28 Jan
Rosen Inn at Pointe Orlando

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.6 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,913 reviews)
"Great place!"
United States
Cristian
The price is ฿5,243
฿5,899 total
includes taxes & fees
9 Feb - 10 Feb
Hyatt House Orlando Airport

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,421 reviews)
"Very nice place to stay with family. "
United States
Anick
The price is ฿4,623
฿5,201 total
includes taxes & fees
23 Jan - 24 Jan
Rosen Shingle Creek

Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,503 reviews)
"Great stay "
United States
Nancy
The price is ฿4,112
฿4,626 total
includes taxes & fees
26 Jan - 27 Jan
Hampton Inn & Suites Orlando Airport @ Gateway Village

Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1,956 reviews)
"Great hotel amazing staff "
United States
Gloria
The price is ฿3,433
฿3,862 total
includes taxes & fees
2 Feb - 3 Feb
Cambria Hotel Orlando Airport

Sonesta Essential Orlando Airport

Sonesta Essential Orlando Airport
3.0 star property
12.2 km from Lake Nona Medical City
8.0 out of 10, Very good, (419 reviews)
"Excellent place to stay "
United States
ALEX
The price is ฿2,501
฿2,814 total
includes taxes & fees
26 Jan - 27 Jan
Sonesta Essential Orlando Airport

Rosen Inn Lake Buena Vista

Rosen Inn Lake Buena Vista
3.5 star property
22 km from Lake Nona Medical City
8.6 out of 10, Excellent, (5,644 reviews)
"Great spot close to parks and restaurants. "
United States
Yashira
The price is ฿3,155
฿3,549 total
includes taxes & fees
1 Feb - 2 Feb
Rosen Inn Lake Buena Vista

Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area
3.0 star property
22.9 km from Lake Nona Medical City
9.8 out of 10, Exceptional, (5,560 reviews)
"Great place"
United States
LUIS
The price is ฿5,010
฿5,637 total
includes taxes & fees
4 Feb - 5 Feb
Drury Plaza Hotel Orlando - Disney Springs Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Downtown Orlando

One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.