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Our top choices for South Central Houston hotels

1. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,173 reviews)
"The bar was great vibes and the morning bartender was the best definitely will visit again soon!"
United States
Brandon
The price is ฿5,108
฿6,358 total
includes taxes & fees
1 Aug - 2 Aug
The Westin Houston Medical Center/Museum District

2. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.4 out of 10, Exceptional, (1,000 reviews)
"Location, staff are great"
United States
Maria Soledad
The price is ฿4,763
฿6,244 total
includes taxes & fees
21 Aug - 22 Aug
InterContinental Houston by IHG

3. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (2,058 reviews)
"Great place to stay at super clean and nice area and everything was nearby"
United States
Marvin
The price is ฿3,659
฿4,320 total
includes taxes & fees
16 Aug - 17 Aug
Hilton Houston Plaza/Medical Center

4. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
8.8 out of 10, Excellent, (67 reviews)
"Amazing stay!!"
Canada
Elizabeth
The price is ฿5,674
฿7,620 total
includes taxes & fees
2 Aug - 3 Aug
Sentral Forme Houston

5. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,011 reviews)
"Everything was excellent! We enjoyed our stay"
Mexico
Pablo
The price is ฿7,776
฿10,424 total
includes taxes & fees
30 Jul - 31 Jul
Hotel Zaza Houston Museum District

6. Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,011 reviews)
"Great AC, Clean room, would stay again"
United States
Haylie
The price is ฿2,483
฿2,905 total
includes taxes & fees
30 Jul - 31 Jul
Americas Best Value Inn Medical Center Downtown

7. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,000 reviews)
"I enjoyed my stay!"
United States
Valencia
The price is ฿4,804
฿6,690 total
includes taxes & fees
28 Aug - 29 Aug
Houston Marriott Medical Center/Museum District

8. Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (215 reviews)
"Parking was great to have on property and very friendly staff! Cleaned rooms and provided anything that was needed!"
United States
Aaliyah
The price is ฿3,223
฿3,771 total
includes taxes & fees
30 Jul - 31 Jul
Downtowner Inns - Houston Downtown

9. La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (589 reviews)
"Lovely property that’s convenient to the Museum District, downtown, and other central Houston attractions. We thoroughly enjoyed our stay. The delicious breakfasts by Chef Joseph deserve special mention, and we appreciated the free parking. Highly recommended."
United States
Melanie
The price is ฿6,009
฿7,031 total
includes taxes & fees
31 Jul - 1 Aug
La Maison in Midtown an urban B&B

10. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (644 reviews)
"Good location for the medical center, and decent rates. The breakfast was very good."
United States
John
The price is ฿4,102
฿4,799 total
includes taxes & fees
28 Aug - 29 Aug
DoubleTree by Hilton Houston Medical Center Hotel & Suites

11. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (217 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is ฿6,949
฿8,634 total
includes taxes & fees
30 Jul - 31 Jul
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

12. Walkable Eado Condo Near Dtwn: Modern + Chic!

Walkable Eado Condo Near Dtwn: Modern + Chic!
3.0 star property
South Central Houston
The price is ฿4,163
฿13,760 total
includes taxes & fees
3 Aug - 4 Aug
Walkable Eado Condo Near Dtwn: Modern + Chic!

13. Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (963 reviews)
"Pretty amazing stay"
United States
DELISA
The price is ฿5,203
฿6,088 total
includes taxes & fees
4 Aug - 5 Aug
Hilton University of Houston

14. Modern 2BR Home With King Beds Near Downtown

Modern 2BR Home With King Beds Near Downtown
2.0 star property
South Central Houston
The price is ฿4,069
฿21,769 total
includes taxes & fees
2 Aug - 3 Aug
Modern 2BR Home With King Beds Near Downtown

15. Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (243 reviews)
"I was pleasantly surprised by how well kept the room was and the staff was very friendly"
United States
Brian
The price is ฿2,014
฿2,356 total
includes taxes & fees
2 Aug - 3 Aug
Southmore Boulevard Motel

16. Scott Inn Suites - Downtown Houston

Scott Inn Suites - Downtown Houston
2.0 star property
South Central Houston
8.4 out of 10, Very good, (47 reviews)
"Nice staff, good clean room and close to public transportation"
United States
Sergio
The price is ฿2,354
฿2,923 total
includes taxes & fees
25 Aug - 26 Aug
Scott Inn Suites - Downtown Houston

17. Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,014 reviews)
"Love the pet friendly property"
United States
Nelda
The price is ฿2,387
฿2,802 total
includes taxes & fees
13 Aug - 14 Aug
Extended Stay America Suites Houston Med Ctr Braeswood Bl

18. MorningSide Inn

MorningSide Inn
2.0 star property
South Central Houston
6.0 out of 10, (522 reviews)
"The staff is very friendly and responsive. We needed some help after check in and they fulfilled all quickly and in a friendly manner. The room was clean. There is no fan. A/C was good but a fan in the sitting area would be good. The bathroom was clean but old looking. The hotel is in a nice neighborhood and it was peaceful and safe. I stayed there with my family for the world cup match. The stadium was very near. We had a peaceful stay and its very value for the money"
United States
Anand
MorningSide Inn

19. Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (210 reviews)
"Excellent stay experience"
United States
Binkeung
The price is ฿2,085
฿2,439 total
includes taxes & fees
8 Aug - 9 Aug
Wanderstay Houston Hostel

20. Houston Hideaway Near Downtown Attractions

Houston Hideaway Near Downtown Attractions
2.0 star property
South Central Houston
The price is ฿2,393
฿18,376 total
includes taxes & fees
3 Aug - 4 Aug
Houston Hideaway Near Downtown Attractions
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
589 reviews
View
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
217 reviews
View
Laptop workspace, blackout curtains, soundproofing
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
215 reviews
View
Outdoor pool, open 6:00 AM to 10:00 PM, pool loungers
InterContinental Houston by IHG
4.0 star property
9.4
Exceptional
1,000 reviews
View
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,173 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hilton Houston Plaza/Medical Center is one of the top choices for your stay in South Central Houston. This hotel is a short 2-minute walk from Rice University, and it offers 2 restaurants and 2 bars. Other good options for your stay in the area include Hotel Zaza Houston Museum District and InterContinental Houston by IHG.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1254 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Twilight Epiphany Skyspace and Cullen Sculpture Garden. Houston Zoo and TDECU Stadium are some other stops worth a visit in the neighbourhood. Daikin Park and Toyota Center are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.