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Our top choices for Hotel Mark Twain hotels

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
0.4 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (3088)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is ฿2,379
฿2,811 total
includes taxes & fees
23 Dec - 24 Dec
Chancellor Hotel on Union Square

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 0.2 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (2655)
"Clean rooms, great location and welcoming staff"
United Kingdom
Simon
The price is ฿4,779
฿7,068 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Nikko San Francisco

citizenM San Francisco Union Square

citizenM San Francisco Union Square
4.0 star property
Union Square, 0.4 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (1428)
"Great location."
United States
Todd
The price is ฿3,711
฿4,367 total
includes taxes & fees
1 Jan - 2 Jan 2026
citizenM San Francisco Union Square

Orchard Hotel

Orchard Hotel
4.0 star property
Chinatown, 0.6 km from Hotel Mark Twain
9.6 out of 10, Exceptional, (1001)
"Wonderful hotel!!!"
United States
Suzanne
The price is ฿3,652
฿4,369 total
includes taxes & fees
22 Dec - 23 Dec
Orchard Hotel

The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco
4.0 star property
0.1 km from Hotel Mark Twain
9.2 out of 10, Wonderful, (1367)
"Staff was amazing. The rooms felt clean and the hotel was very well maintained."
United States
Misty
The price is ฿3,834
฿5,737 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Clift Royal Sonesta San Francisco

Hotel Emblem San Francisco

Hotel Emblem San Francisco
4.0 star property
0.4 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (1003)
"Great place to stay when visiting the City - will return again!"
United States
Chris
The price is ฿3,524
฿5,405 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Emblem San Francisco

White Swan Inn

White Swan Inn
3.5 star property
Union Square, 0.5 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (1005)
"Great place to stay in San Fransisco "
Canada
Daniel
White Swan Inn

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
0.1 km from Hotel Mark Twain
9.0 out of 10, Wonderful, (1111)
"Beautiful hotel with very friendly staff!! Location is also very central, walkable to a lot of restaurants. "
United States
Akila
The price is ฿4,385
฿5,161 total
includes taxes & fees
28 Dec - 29 Dec
The Marker Union Square San Francisco

Marines Memorial Club & Hotel

Marines Memorial Club & Hotel
3.0 star property
0.4 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (20)
"Excellent service, great central location, breakfast and happy hour. "
United States
Meg
The price is ฿5,908
฿6,942 total
includes taxes & fees
29 Dec - 30 Dec
Marines Memorial Club & Hotel

Inn At Union Square

Inn At Union Square
3.5 star property
0.4 km from Hotel Mark Twain
9.2 out of 10, Wonderful, (1010)
"Everything was perfect location staff room and that continental breakfast was delicious Thankyou "
United Kingdom
robert
The price is ฿3,251
฿4,611 total
includes taxes & fees
22 Dec - 23 Dec
Inn At Union Square

Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel
4.0 star property
Union Square, 0.5 km from Hotel Mark Twain
9.2 out of 10, Wonderful, (1815)
"Amazing place"
Australia
David
The price is ฿4,137
฿6,163 total
includes taxes & fees
4 Jan - 5 Jan 2026
Beacon Grand, A Union Square Hotel

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
South of Market, 0.6 km from Hotel Mark Twain
9.4 out of 10, Exceptional, (1003)
"The staff is fantastic"
United States
Brandon
The price is ฿12,092
฿14,232 total
includes taxes & fees
4 Jan - 5 Jan 2026
Four Seasons Hotel San Francisco

HI San Francisco Downtown Hostel

HI San Francisco Downtown Hostel
2.0 star property
Union Square, 0.2 km from Hotel Mark Twain
9.0 out of 10, Wonderful, (370)
"Clean room, friendly staff"
United States
mark ryan
The price is ฿2,233
฿2,600 total
includes taxes & fees
28 Dec - 29 Dec
HI San Francisco Downtown Hostel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square, 0.3 km from Hotel Mark Twain
8.8 out of 10, Excellent, (2793)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is ฿32,955
฿38,786 total
includes taxes & fees
11 Jan - 12 Jan 2026
Handlery Union Square Hotel

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square, 0.6 km from Hotel Mark Twain
9.2 out of 10, Wonderful, (1002)
"Wonderful Staff and hospitality."
United States
Rachel
The price is ฿5,591
฿7,664 total
includes taxes & fees
25 Dec - 26 Dec
Taj Campton Place

Cornell Hotel de France

Cornell Hotel de France
3.5 star property
0.5 km from Hotel Mark Twain
9.0 out of 10, Wonderful, (1002)
"Room was clean and comfortable, staff was friendly. Overall great stay. "
United States
Nia
The price is ฿2,910
฿4,053 total
includes taxes & fees
22 Dec - 23 Dec
Cornell Hotel de France

Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG
4.0 star property
< 0.1 km from Hotel Mark Twain
8.8 out of 10, Excellent, (1277)
"Good location and great price. "
United States
Brienne
The price is ฿3,444
฿5,162 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Spero, Vignette Collection by IHG

InterContinental San Francisco by IHG

InterContinental San Francisco by IHG
4.0 star property
South of Market, 0.7 km from Hotel Mark Twain
9.2 out of 10, Wonderful, (1030)
"Love this hotel in SF."
United States
JONATHAN
The price is ฿5,088
฿7,282 total
includes taxes & fees
25 Dec - 26 Dec
InterContinental San Francisco by IHG

The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square
4.5 star property
Union Square, 0.4 km from Hotel Mark Twain
8.8 out of 10, Excellent, (2419)
"Always a great place to stay "
United States
Susan
The price is ฿5,313
฿7,558 total
includes taxes & fees
26 Dec - 27 Dec
The Westin St. Francis San Francisco on Union Square

Hotel G San Francisco

Hotel G San Francisco
4.0 star property
0.3 km from Hotel Mark Twain
9.0 out of 10, Wonderful, (1002)
"Great hotel! Spacious room, friendly staff. "
United States
Courtney
Hotel G San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotel Mark Twain Hotel Reviews

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Frequently asked questions

What's the area like around Hotel Mark Twain?
Hotel Mark Twain is located in San Francisco. This metropolitan area is known for its major shopping area and stunning architecture. If you're looking for a convenient place to stay, take a look at the 944 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Hotel Mark Twain?
Adjacent to Hotel Mark Twain, Chancellor Hotel on Union Square is one of the top choices for your stay based on our traveller data, and this hotel offers a bar and free WiFi. Other good choices within a short distance include Fairmont San Francisco and Holiday Inn Golden Gateway by IHG.
How many hotels are there near Hotel Mark Twain?
Expedia has 944 hotels and other accommodation options within a mile from Hotel Mark Twain.
If I need to cancel the hotel reservation for my stay near Hotel Mark Twain, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available near Hotel Mark Twain.
What can I see and do near Hotel Mark Twain?
Study the collections at Asian Art Museum of San Francisco, San Francisco Museum of Modern Art or Cable Car Museum. Sights like Golden Gate Bridge, San Francisco Mint and 450 Sutter Building are landmarks to visit in the area. You can watch performances at SHN Curran Theatre, Warfield Theatre and Golden Gate Theatre if you're interested in local theatre.
How can I get to Hotel Mark Twain?
You can take advantage of metro transport at Powell St & Geary Blvd Stop, Powell St & Post St Stop and Powell St & O'Farrell St Stop. If you'd like to venture around the area nearby, you may want a car rental for your journey.