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25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,005 reviews)
"Convenient hotel, clean and near restaurant options."
United States
Ivette
The price is ฿3,643
฿4,081 total
includes taxes & fees
8 Oct - 9 Oct
Hyatt Place Florence Downtown
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

2. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,729 reviews)
"Very nice place to stay"
United States
HOMERO
The price is ฿2,140
฿2,396 total
includes taxes & fees
24 Sept - 25 Sept
Howard Johnson by Wyndham Florence
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

3. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is ฿4,354
฿5,206 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

4. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,448 reviews)
"Great location, friendly staff."
United States
Windia
The price is ฿2,958
฿3,313 total
includes taxes & fees
4 Oct - 5 Oct
Park Inn by Radisson Florence, SC
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

5. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (985 reviews)
"Nice stay"
United States
Michelle
The price is ฿3,911
฿4,380 total
includes taxes & fees
7 Oct - 8 Oct
Hampton Inn & Suites Florence-North-I-95
A restaurant with brick walls, framed awards, and a bar area.

6. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (655 reviews)
"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"
United States
Ankh
The price is ฿4,210
฿4,715 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Florence, Tapestry Collection by Hilton
A hotel lobby with a reception desk, seating area, and a television screen.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,368 reviews)
"Breakfast was excellent. Room was clean and quiet."
United States
Mila
The price is ฿3,350
฿3,752 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn & Suites Florence Center Area
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

8. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (300 reviews)
"Very good stay"
United States
Michelle
The price is ฿2,689
฿3,142 total
includes taxes & fees
18 Oct - 19 Oct
Spark by Hilton Florence North I-95, SC
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

9. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Excellent quick stay while traveling. Very clean room and easy check in and out."
United States
Tiffany
The price is ฿3,233
฿3,818 total
includes taxes & fees
7 Oct - 8 Oct
Tru by Hilton Florence I-95
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

10. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,000 reviews)
The price is ฿2,894
฿3,373 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites Florence I-95
A hotel entrance with a stone facade, glass doors, and a number '501' above.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (659 reviews)
"I have stayed here a few times and it’s always nice place to stay all around. Will continue to make this my go to hotel in Florence."
United States
Felecia
The price is ฿4,195
฿4,698 total
includes taxes & fees
22 Oct - 23 Oct
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (905 reviews)
"Always a good stay"
United Kingdom
William
The price is ฿3,913
฿4,383 total
includes taxes & fees
24 Sept - 25 Sept
TownePlace Suites by Marriott Florence
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (1,000 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is ฿4,206
฿4,711 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

14. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,507 reviews)
"Very convenient location Friendly and helpful staff"
United States
Heather
The price is ฿2,832
฿3,172 total
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

15. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (971 reviews)
"The room was clean, and staff were very helpful and friendly. The breakfast was good. Will stay again."
United States
Bill
The price is ฿3,674
฿4,115 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Florence Center
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

16. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (1,000 reviews)
"The room was incredible, the people were sweet and amazing food was great"
United States
Denay
The price is ฿4,471
฿5,008 total
includes taxes & fees
27 Sept - 28 Sept
Staybridge Suites Florence - Civic Center by IHG
A swimming pool with lounge chairs and a building with balconies.

17. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (376 reviews)
"-clean rooms, dog friendly and comfy bed."
Canada
Noémie
The price is ฿3,160
฿3,539 total
includes taxes & fees
2 Oct - 3 Oct
Quality Inn & Suites Florence Civic Center

18. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
10.4 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (1,001 reviews)
"Great for families"
United States
saleh
The price is ฿3,504
฿4,121 total
includes taxes & fees
29 Sept - 30 Sept
Home2 Suites by Hilton Florence, SC
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

19. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (223 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
The price is ฿2,385
฿2,671 total
includes taxes & fees
19 Oct - 20 Oct
Affordable Suites Florence
A hotel with a modern design, multiple floors, and a parking lot.

20. Best Western Inn

Best Western Inn
2.5 star property
7.2 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,002 reviews)
"Great Stay!"
United States
Jamie
The price is ฿2,948
฿3,301 total
includes taxes & fees
24 Sept - 25 Sept
Best Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
Hyatt Place Florence Downtown
3.0 star property
9.0
Wonderful
1,005 reviews
View
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,729 reviews
View
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.6
Excellent
1,000 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,448 reviews
View
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
Hampton Inn & Suites Florence-North-I-95
2.5 star property
9.0
Wonderful
985 reviews
View

Top Florence Regional Hotel Reviews

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent
"We stop here a few times a year on our pilgrimage from NJ to Fl with our dogs. It’s conveniently located, staff is friendly, rooms are clean, bfast in the Am - and it’s very affordable."
rachael 1-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Florence

Guide to exploring Florence Regional

Florence Regional hotels information

Number of reviews
9,943
Accommodation
137 hotels
Lowest Price
฿2,396
Highest Price
฿5,206

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 72 hotels and other accommodations within a few miles of the airport for a convenient home base.

Where is the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other choices near the airport include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find close to Florence, SC (FLO-Florence Regional)?

Expedia has 72 hotels and other accommodation options a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center and CarolinaBank Field.