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Check prices for these dates

This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,000 reviews)
"Convenient hotel, clean and near restaurant options."
United States
Ivette
The price is ฿3,643
฿4,081 total
includes taxes & fees
5 Oct - 6 Oct
Hyatt Place Florence Downtown
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

2. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,730 reviews)
"Very nice place to stay"
United States
HOMERO
The price is ฿2,140
฿2,396 total
includes taxes & fees
27 Sept - 28 Sept
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

3. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,449 reviews)
"Great location, friendly staff."
United States
Windia
The price is ฿2,958
฿3,313 total
includes taxes & fees
4 Oct - 5 Oct
Park Inn by Radisson Florence, SC
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

4. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is ฿4,339
฿5,187 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A restaurant with brick walls, framed awards, and a bar area.

5. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (655 reviews)
"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"
United States
Ankh
The price is ฿4,210
฿4,715 total
includes taxes & fees
19 Oct - 20 Oct
Hotel Florence, Tapestry Collection by Hilton
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

6. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (985 reviews)
"Nice stay"
United States
Michelle
The price is ฿3,911
฿4,380 total
includes taxes & fees
30 Sept - 1 Oct
Hampton Inn & Suites Florence-North-I-95
A hotel lobby with a reception desk, seating area, and a television screen.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,368 reviews)
"Breakfast was excellent. Room was clean and quiet."
United States
Mila
The price is ฿3,350
฿3,752 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn & Suites Florence Center Area
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

8. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,000 reviews)
"Very convenient to highway"
United States
Denise
The price is ฿2,894
฿3,373 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites Florence I-95
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

9. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,000 reviews)
"Excellent quick stay while traveling. Very clean room and easy check in and out."
United States
Tiffany
The price is ฿3,232
฿3,817 total
includes taxes & fees
30 Sept - 1 Oct
Tru by Hilton Florence I-95
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

10. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (905 reviews)
"Always a good stay"
United Kingdom
William
The price is ฿3,913
฿4,383 total
includes taxes & fees
27 Sept - 28 Sept
TownePlace Suites by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (659 reviews)
"I have stayed here a few times and it’s always nice place to stay all around. Will continue to make this my go to hotel in Florence."
United States
Felecia
The price is ฿4,195
฿4,698 total
includes taxes & fees
27 Sept - 28 Sept
Fairfield Inn & Suites by Marriott Florence I-20
A spacious lobby with a reception desk, seating area, and large windows.

12. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (350 reviews)
The price is ฿3,775
฿4,228 total
includes taxes & fees
4 Oct - 5 Oct
Hilton Garden Inn Florence
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

13. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (376 reviews)
"-clean rooms, dog friendly and comfy bed."
Canada
Noémie
The price is ฿3,160
฿3,539 total
includes taxes & fees
2 Oct - 3 Oct
Quality Inn & Suites Florence Civic Center
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

14. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (1,000 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is ฿4,206
฿4,711 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

15. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (300 reviews)
"Very good stay"
United States
Michelle
The price is ฿2,689
฿3,142 total
includes taxes & fees
18 Oct - 19 Oct
Spark by Hilton Florence North I-95, SC
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

16. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (971 reviews)
"The room was clean, and staff were very helpful and friendly. The breakfast was good. Will stay again."
United States
Bill
The price is ฿3,674
฿4,115 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Florence Center
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

17. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (223 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
The price is ฿2,385
฿2,671 total
includes taxes & fees
19 Oct - 20 Oct
Affordable Suites Florence
A hotel with a modern design, multiple floors, and a parking lot.

18. Best Western Inn

Best Western Inn
2.5 star property
7.2 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,003 reviews)
"Great Stay!"
United States
Jamie
The price is ฿2,948
฿3,301 total
includes taxes & fees
27 Sept - 28 Sept
Best Western Inn
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

19. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,507 reviews)
"Very convenient location Friendly and helpful staff"
United States
Heather
The price is ฿2,832
฿3,172 total
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Florence
An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

20. Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
10.8 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (731 reviews)
"Great place to stop for the night!"
United States
tracy
The price is ฿3,150
฿3,856 total
includes taxes & fees
4 Oct - 5 Oct
Homewood Suites by Hilton Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
Hyatt Place Florence Downtown
3.0 star property
9.0
Wonderful
1,000 reviews
View
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,730 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,449 reviews
View
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.6
Excellent
1,000 reviews
View
A restaurant with brick walls, framed awards, and a bar area.
Hotel Florence, Tapestry Collection by Hilton
3.0 star property
8.8
Excellent
655 reviews
View

Top Florence Regional Hotel Reviews

Best Western Inn

Best Western Inn

8/10 Good
"Front desk staff was helpful and friendly. My room was clean and the bed was comfortable. The breakfast was very good. Nice to have scrambled eggs and some sausage links for protein plus many other things too. Folgers coffee on tap is awesome!! I would stay here again 4.5 out of 5."
Lee 1-night trip
Posted 1 hour ago
Best Western Inn

Guide to exploring Florence Regional

Florence Regional hotels information

Number of reviews
11,021
Accommodation
137 hotels
Lowest Price
฿2,396
Highest Price
฿5,187

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 72 hotels and other accommodations within a few miles of the airport for a convenient home base.

Where is the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other choices near the airport include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find close to Florence, SC (FLO-Florence Regional)?

Expedia has 72 hotels and other accommodation options a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center and CarolinaBank Field.