Mission Bay Travel Guide

San Diego

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Stay near popular Mission Bay attractions

Things to do


Top hotels in Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿7,269 per night from 31 Oct to 1 Nov
฿7,269
฿10,143 total
31 Oct - 1 Nov
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Paradise Point Resort & Spa
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
The price is ฿6,722 per night from 29 Oct to 30 Oct
฿6,722
฿9,513 total
29 Oct - 30 Oct
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Hyatt Regency Mission Bay Spa and Marina
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is ฿6,048 per night from 4 Nov to 5 Nov
฿6,048
฿7,923 total
4 Nov - 5 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,487 reviews)
"Nice hotel, clean room, and comfortable bed. They really need to do something about the cockroaches though. The disinfectant spray when they clean was a bit overwhelming."

Reviewed on 28 Oct 2026

The Dana on Mission Bay
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
The price is ฿7,738 per night from 15 Nov to 16 Nov
฿7,738
฿10,681 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this spa resort in San Diego. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
San Diego Mission Bay Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is ฿5,139 per night from 1 Nov to 2 Nov
฿5,139
฿7,134 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,344 reviews)
"Nice clean room, central located to walking activities. It's nice to have a view of the bay but not nice to look onto the dirty roof tops of the buildings in front of us. That I do not know if they can do anything about. On a nicer note we spoke with a lovely lady about different eating places we ..."

Reviewed on 28 Oct 2026

Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is ฿5,235 per night from 22 Nov to 23 Nov
฿5,235
฿7,701 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (4,562 reviews)
"Had trouble with my key during the stay it was very unpleasant going twice up and down to the lobby. On top of that the bed was dirty underneath."

Reviewed on 28 Oct 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Point Loma

Seaside views a bustling port and top sights from Marine Corps Recruit Depot to Shelter Island – discover Point Loma, a destination also famous for its island views.



Mission Bay Travel Guide