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Find hotels in Upstate South Carolina, SC from ฿2,122
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Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels

8.6 out of 10, Excellent, (424)
The price is ฿2,421
฿2,639 total
includes taxes & fees
5 Jan - 6 Jan 2026

9.4 out of 10, Exceptional, (219)
The price is ฿4,342
฿4,820 total
includes taxes & fees
3 Jan - 4 Jan 2026

8.8 out of 10, Excellent, (1001)
The price is ฿2,418
฿2,684 total
includes taxes & fees
9 Jan - 10 Jan 2026

9.0 out of 10, Wonderful, (1000)
The price is ฿3,383
฿4,199 total
includes taxes & fees
28 Dec - 29 Dec

9.2 out of 10, Wonderful, (1000)
The price is ฿3,414
฿3,755 total
includes taxes & fees
3 Jan - 4 Jan 2026

8.0 out of 10, Very good, (665)
The price is ฿2,281
฿2,694 total
includes taxes & fees
4 Jan - 5 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cottage

9.8 out of 10, Exceptional, (9)
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Stay near popular Southeastern United States attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Michelle Hendrix
Open Photo by Michelle Hendrix
Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
10/10 Excellent

ECHO Suites Extended Stay by Wyndham Spartanburg
10/10 Excellent
More cheap stays in Upstate South Carolina

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is ฿1,952 per night from 30 Dec to 31 Dec
฿1,952
฿2,167 total
30 Dec - 31 Dec
includes taxes & fees
7.8/10 Good! (1,001 reviews)














































































































































