A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Check availability on St. Louis Luxury Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for St. Louis luxury hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is ฿12,666
฿14,811 total
includes taxes & fees
8 Nov - 9 Nov
Four Seasons Hotel St Louis
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (586 reviews)
  • cleanliness
    Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
The price is ฿19,557
฿22,830 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,080 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is ฿5,377
฿6,845 total
includes taxes & fees
17 Nov - 18 Nov
Ameristar Casino Resort and Spa
A modern lobby with a large glass sphere, seating areas, and a reception desk.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,148 reviews)
  • cleanliness
    Indulge in artistic luxury at this city centre St. Louis hotel with spa services and indoor pool.
The price is ฿4,852
฿5,842 total
includes taxes & fees
22 Nov - 23 Nov
21C Museum Hotel St Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

5. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,009 reviews)
  • cleanliness
    Opulent city centre retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
The price is ฿4,429
฿5,179 total
includes taxes & fees
15 Nov - 16 Nov
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,012 reviews)
  • cleanliness
    Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
The price is ฿4,526
฿6,333 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

7. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
The price is ฿4,683
฿5,431 total
includes taxes & fees
20 Nov - 21 Nov
DoubleTree by Hilton Hotel St. Louis - Chesterfield
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

8. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,015 reviews)
The price is ฿4,323
฿5,135 total
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Brentwood
A person sitting on a bed with a laptop, a vase with flowers, and a lamp on a bedside table.

9. Hyatt Centric Downtown St. Louis

Hyatt Centric Downtown St. Louis
4.5 star property
Downtown West
7.6 out of 10, Good, (1,000 reviews)
The price is ฿4,562
฿5,380 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Centric Downtown St. Louis
A large white building with a central tower, a parking lot, and a tree with red leaves.

10. The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (175 reviews)
The price is ฿4,560
฿5,191 total
includes taxes & fees
2 Nov - 3 Nov
The Inn at Elijah McLeans
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Louis Hotel Reviews

The Westin St. Louis

The Westin St. Louis

10/10 Excellent
"Room was clean, staff helpful. Super close to stadium"
Kassidy 1-night trip
Posted less than an hour ago
The Westin St. Louis

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in St. Louis?
Travel to Lambert-St. Louis International Airport (STL) Airport or Belleville, IL (BLV-MidAmerica-St. Louis) Airport, and then treat yourself to a stay at one of 8 St. Louis luxury hotels. Known for its art and theatre, St. Louis also has some interesting things to see and do including St. Louis Union Station and St. Louis Zoo, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in St. Louis?
21C Museum Hotel St Louis is a luxury hotel with spa services and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. St. Louis Union Station Hotel, Curio Collection by Hilton and Ameristar Casino Resort and Spa are other upscale choices for your stay.
How many luxury hotels will I find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 8 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Louis is 1374 mm.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, St. Louis Zoo and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see The St. Louis Wheel and Energizer Park.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transport at Stadium Station, 8th and Pine Station and Convention Center Station.