Downtown West Travel Guide

St. Louis

An ornate hall with arched ceilings and intricate patterns.
A city skyline with a prominent arch bridge over a river.
A city skyline at sunset with prominent buildings and a visible contrail in the sky.
A baseball stadium surrounded by urban buildings and a hotel.
A grand cathedral interior with a large circular dome, ornate columns, and a central altar.

Stay near popular Downtown West attractions

Things to do


Top hotels in Downtown West

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
The price is ฿3,212 per night from 20 Sept to 21 Sept
฿3,212
฿3,756 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge) and a 24-hour front desk. Our guests praise the helpful staff ...
Home2 Suites by Hilton St. Louis Downtown
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is ฿4,729 per night from 27 Sept to 28 Sept
฿4,729
฿5,694 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
21C Museum Hotel St Louis
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

2.5 out of 5
1221 Locus Street St. Louis MO
The price is ฿3,212 per night from 13 Sept to 14 Sept
฿3,212
฿3,756 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the helpful staff and the clean rooms in their ...
Tru By Hilton St. Louis Downtown
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is ฿3,851 per night from 13 Sept to 14 Sept
฿3,851
฿4,503 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
8.8/10 Excellent! (2,180 reviews)
"Loved staying here. It's within walking distance of the union station restaurants, the aquarium and the observation wheel. We really enjoyed the nightly social hour. Our room had everything we needed and the bed was very comfortable. The bathroom was small but stocked and in good order. The staff ..."

Reviewed on 6 Sept 2026

Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
The price is ฿4,444 per night from 13 Sept to 14 Sept
฿4,444
฿5,285 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,536 reviews)
"Couldn’t be happier with our experience!"

Reviewed on 6 Sept 2026

Drury Plaza Hotel St. Louis Union Station
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
The price is ฿4,804 per night from 20 Sept to 21 Sept
฿4,804
฿5,714 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, an outdoor pool and 7 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown West

Find the best Downtown West areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.



Downtown West Travel Guide