The Best Hotels Closest to Six Mile Cypress Slough Preserve in Fort Myers - 2026 Updated Prices

A wooden boardwalk through a dense forest with green foliage and a clear blue sky.

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Our top choices for Six Mile Cypress Slough Preserve hotels

A gym with treadmills, dumbbells, and a sign indicating free Wi-Fi in all rooms.

A hotel room with two beds, a desk, a chair, a TV, and a window.

A laundry facility with multiple washing machines and dryers, a wooden floor, and a door.

A multi-story hotel with a flat roof, a central entrance, and a parking lot in front.

1. HomeTowne Studios by Red Roof Fort Myers

3 km from Six Mile Cypress Slough Preserve

฿1,963

฿2,189 total

includes taxes & fees

16 Sept - 17 Sept

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building.

A hotel room with a TV, sofa, coffee table, desk, and a bathroom visible in the background.

A breakfast buffet with various food options, including cereals, pastries, and a sign indicating gluten-free items.

2. Best Western Fort Myers Inn & Suites

3.5 km from Six Mile Cypress Slough Preserve

William

฿2,172

฿2,421 total

includes taxes & fees

20 Sept - 21 Sept

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A reception desk with a sign reading "Comfort Inn & Suites" and two monitors on either side.

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

3. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

Carmen

฿1,955

฿2,180 total

includes taxes & fees

20 Sept - 21 Sept

A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A paved outdoor area with palm trees, string lights, and outdoor seating.

A hotel room with a bed, desk, chair, TV, and a bathroom visible through an open door.

4. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor, 6.3 km from Six Mile Cypress Slough Preserve

Brandon

฿3,338

฿3,722 total

includes taxes & fees

21 Sept - 22 Sept

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

A hotel lobby with a reception desk, a seating area with a sofa and chairs, a kitchenette, and a 'Welcome to Hampton' sign.

A modern lounge area with a sofa, two yellow ottomans, a small round table, and a printer on a wooden side table.

A pool area with lounge chairs, a gazebo, and a blue umbrella.

5. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor, 3.6 km from Six Mile Cypress Slough Preserve

Denise

฿2,412

฿2,689 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

A hotel lobby with a reception desk, seating area, and a restaurant.

A gym with treadmills, elliptical machines, and a stationary bike.

A modern lobby with a staircase, seating area, and a reception desk.

6. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

Renny

฿2,171

฿2,421 total

includes taxes & fees

14 Sept - 15 Sept

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

A modern living room with a grey sofa, a wooden accent wall, a coffee table with a plant, and sheer curtains allowing natural light.

An outdoor patio area with tables and chairs, string lights, and potted plants.

A modern reception area with a large abstract mural, a wooden reception desk, and a seating area with a long table and chairs.

7. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas, 5.2 km from Six Mile Cypress Slough Preserve

heather

฿3,200

฿3,568 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

A hotel with a swimming pool, outdoor seating, and a sign indicating a 5 ft depth limit.

A spacious lobby with a central seating area, a reception desk, and a vending machine.

A modern hotel with a covered entrance, multiple floors, and a landscaped area with plants and outdoor seating.

8. Home2 Suites by Hilton Fort Myers Colonial Blvd

3.5 km from Six Mile Cypress Slough Preserve

Karon

฿3,632

฿4,049 total

includes taxes & fees

20 Sept - 21 Sept

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

A modern kitchen with a microwave, sink, and wooden shelves.

A modern kitchen area with a bar counter, seating, and a coffee station.

A hotel room with two beds, wooden headboards, white bedding, a nightstand, a lamp, and a window with a view.

9. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor, 5.6 km from Six Mile Cypress Slough Preserve

Robert

฿1,963

฿2,189 total

includes taxes & fees

14 Sept - 15 Sept

A hotel room with a bed, a desk with a chair, a television, and a door.

A gym with treadmills, a mirrored wall, and a wooden floor.

A conference room with tables, chairs, a projector screen, and patterned carpet.

A modern kitchen with a central island, wooden cabinets, and a blue accent wall.

10. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes, 9.8 km from Six Mile Cypress Slough Preserve

Mark

฿3,635

฿4,053 total

includes taxes & fees

16 Sept - 17 Sept

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

A modern kitchen with a coffee station, stainless steel appliances, and wooden cabinets.

A modern hotel lobby with a central counter, two refrigerators stocked with beverages, and shelves with snacks.

A modern hotel room with a bed, a desk, a sofa, and a red ottoman.

11. Comfort Suites Fort Myers East I-75

9.6 km from Six Mile Cypress Slough Preserve

Richard

฿2,981

฿3,324 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

A modern hotel room with a bed, bedside tables, a lamp, a nightstand, a built-in kitchen with a refrigerator, microwave, and cabinets.

A modern kitchen with wooden cabinets, a white countertop, and a fruit basket.

A modern living room with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a ceiling light fixture.

12. TownePlace Suites by Marriott Fort Myers Gulf Coast

9.3 km from Six Mile Cypress Slough Preserve

Jameasha

฿3,074

฿3,427 total

includes taxes & fees

18 Sept - 19 Sept

A breakfast bar with various food items and beverages, a coffee station, and a fruit bowl.

A coffee shop with a 'The Shop' sign, a refrigerated section, and a variety of snacks and beverages.

A modern reception area with a central counter, a bar, and a seating area.

13. Hilton Garden Inn Fort Myers Airport/FGCU

Miromar Lakes, 9.7 km from Six Mile Cypress Slough Preserve

Joey

฿3,117

฿3,475 total

includes taxes & fees

19 Sept - 20 Sept

An outdoor patio with a barbecue area, seating, and string lights.

A hotel lobby with seating areas, a kitchen in the background, and a ceiling fan.

A hotel room with a bed, a desk, a chair, a sofa, a mirror, and artwork on the walls.

A lobby with a sofa, two armchairs, a coffee table, a fish tank, and a dining area.

14. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes, 9.7 km from Six Mile Cypress Slough Preserve

Kieran

฿3,252

฿3,626 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows.

A rooftop patio with outdoor seating, a pool, and palm trees.

A modern living room with a blue sofa, red armchairs, and a coffee table. There are two lamps and a wall art piece above the sofa.

15. Hampton Inn & Suites Fort Myers - Colonial Blvd

3.4 km from Six Mile Cypress Slough Preserve

Marcos

฿3,279

฿3,656 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel reception area with a wooden reception desk, a digital phone, and a self-service beverage dispenser.

16. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Villas, 6.1 km from Six Mile Cypress Slough Preserve

Adelaide

฿2,618

฿2,919 total

includes taxes & fees

19 Sept - 20 Sept

A hotel room with a bed, a desk, a chair, and a small table.

A pool area with lounge chairs and a pergola, surrounded by palm trees and a building with multiple windows.

A modern kitchen with wooden cabinets, a built-in sink, and a coffee maker.

A hotel with a curved entrance, multiple floors, and a parking area.

17. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor, 3.8 km from Six Mile Cypress Slough Preserve

Michael

฿3,107

฿3,464 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

A modern hotel lobby with a seating area, a reception desk, and a flat-screen TV.

A hotel room with a bed, a desk with a computer, a chair, a sofa, a mirror, and a nightstand with a lamp.

A multi-story hotel with a modern design, featuring a parking lot and a covered entrance area.

18. Home2 Suites by Hilton Fort Myers Airport

8.2 km from Six Mile Cypress Slough Preserve

Elio

฿3,632

฿4,049 total

includes taxes & fees

22 Sept - 23 Sept

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

A Hampton Inn hotel with a well-lit entrance, a covered outdoor area, and a parking lot.

A gym with treadmills, exercise bikes, and a weightlifting area.

19. Hampton Inn Fort Myers Downtown

Fort Myers River District, 8.8 km from Six Mile Cypress Slough Preserve

Craig

฿3,393

฿3,783 total

includes taxes & fees

22 Sept - 23 Sept

A hotel room with a bed, a desk with a chair, a sofa, a large window with curtains, and a framed picture on the wall.

A hotel lobby with a reception desk, a sofa, and a dining area with chairs and tables.

20. Quality Inn & Suites Lehigh Acres Fort Myers

17.2 km from Six Mile Cypress Slough Preserve

Claudia

฿1,943

฿2,166 total

includes taxes & fees

11 Oct - 12 Oct

View all properties

Compare popular hotels close to Six Mile Cypress Slough Preserve

Property	Property class	Guest rating
HomeTowne Studios by Red Roof Fort Myers	9.0 Wonderful 79 reviews	View
Best Western Fort Myers Inn & Suites	8.8 Excellent 1,223 reviews	View
Comfort Inn & Suites Fort Myers Airport	8.8 Excellent 1,146 reviews	View
Holiday Inn Express & Suites Fort Myers Airport by IHG	9.6 Exceptional 1,205 reviews	View
Hampton Inn Fort Myers-Airport & I-75	9.0 Wonderful 1,005 reviews	View

Top Six Mile Cypress Slough Preserve Hotel Reviews

Best Western Fort Myers Inn & Suites

8/10 Good

"Liked the breakfast, staff. The bathroom needed an upgrade. We liked the location."

SpringHill Suites by Marriott Fort Myers Airport

10/10 Excellent

"Great hotel. Spacious room. Walking distance to multiple restaurants. No airport noise, very quiet. Would gladly stay here again"

Quality Suites Fort Myers I-75

10/10 Excellent

"Good"

Courtyard by Marriott Fort Myers Cape Coral

10/10 Excellent

"Very clean"

Quality Inn Fort Myers Cape Coral

8/10 Good

"Staff at front desk was nice, staff at breakfast not so much we did come in at closing but don’t have to be rude about it. Rooms were nice and cold ac - for the price not bad at all."

Landing Fort Myers Near Highland Pines

10/10 Excellent

"Very Clean"

Stay Well Inn & Suites

10/10 Excellent

"👍"

Residence Inn by Marriott Fort Myers

8/10 Good

"Its a much older hotel and it looks like it. The Air conditioner in the room was working and you could hear it. They only had one person trying to handle breakfast in the morning, cleaning, cooking, restocking, customer service and that was an impossible task even if there were only 10-20 people there. We ended up going out to breakfast because they ran out of food and I didn't want to further stress out the man who was clearly already stressed. This is our brand of hotel we stay at for all of our Disney Trips and this one wasn't quite what we expected when compared to the Orlando counterparts."

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Catch an event at Brookshire Bath and Tennis Club during your trip to Fort Myers.

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Topgolf

You can take time to visit Topgolf during your travels to Fort Myers. Amble around the area's beautiful beaches or attend a baseball game.

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Hammond Stadium

Catch an event at Hammond Stadium during your trip to Fort Myers.

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Lee Health Sports Complex

8.6/10 (432 reviews)

Catch an event at Lee Health Sports Complex during your trip to Fort Myers. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.

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Calusa Nature Center and Planetarium

You can spend time browsing the exhibits at Calusa Nature Center and Planetarium in Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.

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Eagle Ridge Golf Club

Enjoy a round of golf in Fort Myers at Eagle Ridge Golf Club. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

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The Ranch Concert Hall & Saloon

You can get tickets for a performance at The Ranch Concert Hall & Saloon during your trip to Fort Myers. In the area, take in the entertainment choices and beautiful sunsets.

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Regal Belltower

You can take time to visit Regal Belltower during your travels to Fort Myers. Amble around this relaxing area's beautiful beaches and enjoy its top-notch restaurants.

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Frequently asked questions

What's the area like around Six Mile Cypress Slough Preserve?

Six Mile Cypress Slough Preserve is located in a family-friendly area of Fort Myers known for its beautiful beaches and bird watching. If you're looking for a convenient place to stay, take a look at the 20 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Six Mile Cypress Slough Preserve?

Landing Fort Myers Near Highland Pines is one of the top choices for your stay based on our traveller data, and this aparthotel offers an outdoor pool and free parking. It's located just a short 1 mi (1.6 km) from Six Mile Cypress Slough Preserve. Other good choices within 5 miles include Baymont by Wyndham Fort Myers Central and HomeTowne Studios by Red Roof Fort Myers.

How many hotels are there close to Six Mile Cypress Slough Preserve?

Expedia has 20 hotels and other accommodation options within a mile from Six Mile Cypress Slough Preserve.

If I need to cancel the hotel reservation for my stay near Six Mile Cypress Slough Preserve, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals available near Six Mile Cypress Slough Preserve.

What can I see and do near Six Mile Cypress Slough Preserve?

You can check out the local talent at Barbara B Mann Hall, The Ranch Concert Hall & Saloon and Broadway Palm Dinner Theatre. You might spend a leisurely day outdoors at Lakes Regional Park and Dunbar Park. Calusa Nature Center and Planetarium, Alliance for the Arts and Railroad Museum of South Florida are fun stops for the whole family while you're in town.

Search Hotels Near Six Mile Cypress Slough Preserve, Fort Myers

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Our top choices for Six Mile Cypress Slough Preserve hotels

1. HomeTowne Studios by Red Roof Fort Myers

2. Best Western Fort Myers Inn & Suites

3. Comfort Inn & Suites Fort Myers Airport

4. Holiday Inn Express & Suites Fort Myers Airport by IHG

5. Hampton Inn Fort Myers-Airport & I-75

6. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

7. Doubletree by Hilton Fort Myers at Bell Tower Shops

8. Home2 Suites by Hilton Fort Myers Colonial Blvd

9. Extended Stay America Premier Suites - Fort Myers - Airport

10. Drury Inn & Suites Fort Myers Airport FGCU

11. Comfort Suites Fort Myers East I-75

12. TownePlace Suites by Marriott Fort Myers Gulf Coast

13. Hilton Garden Inn Fort Myers Airport/FGCU

14. Homewood Suites by Hilton Fort Myers Airport/FGCU

15. Hampton Inn & Suites Fort Myers - Colonial Blvd

16. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

17. SpringHill Suites by Marriott Fort Myers Airport

18. Home2 Suites by Hilton Fort Myers Airport

19. Hampton Inn Fort Myers Downtown

20. Quality Inn & Suites Lehigh Acres Fort Myers

Compare popular hotels close to Six Mile Cypress Slough Preserve

Top Six Mile Cypress Slough Preserve Hotel Reviews

Best Western Fort Myers Inn & Suites

SpringHill Suites by Marriott Fort Myers Airport

Quality Suites Fort Myers I-75

Courtyard by Marriott Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

Landing Fort Myers Near Highland Pines

Stay Well Inn & Suites

Residence Inn by Marriott Fort Myers

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Topgolf

Hammond Stadium

Lee Health Sports Complex

Calusa Nature Center and Planetarium

Eagle Ridge Golf Club

The Ranch Concert Hall & Saloon

Regal Belltower

Frequently asked questions