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Check prices for these dates

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

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Our top choices for Sioux Empire Medical Museum hotels

Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.8 out of 10, Exceptional, (175 reviews)
"Beautiful and well appointed hotel with great staff, comfy beds, and all you're looking for in a nice getaway."
United States
Elysa
The price is ฿7,368
฿8,149 total
includes taxes & fees
25 Jul - 26 Jul
Highpoint Hotel
Terrace/patio

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (654 reviews)
"Great staff, Clean rooms, very pet friendly, couldn't ask for a better place to stay!"
United States
Mike
The price is ฿4,868
฿5,406 total
includes taxes & fees
12 Jul - 13 Jul
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Interior detail

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,468 reviews)
"Very nice hotel and charming bar."
United States
Susan
The price is ฿6,390
฿7,076 total
includes taxes & fees
20 Jul - 21 Jul
Hotel On Phillips
Exterior detail

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,119 reviews)
"Very nice motel, highly recommended."
United States
Roseann
The price is ฿4,172
฿5,009 total
includes taxes & fees
26 Jul - 27 Jul
Clubhouse Hotel Suites Sioux Falls
Meeting facility

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (227 reviews)
"Great location. Easy parking options. Walkable to almost anything you want to do! Contemporary interior. Beds and showers are great!"
United States
Courtney
The price is ฿6,230
฿7,033 total
includes taxes & fees
26 Jul - 27 Jul
Canopy By Hilton Sioux Falls Downtown
Exterior

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,003 reviews)
"Great place to stay and excellent location."
United States
Chris
The price is ฿4,487
฿4,989 total
includes taxes & fees
2 Aug - 3 Aug
Hampton Inn Sioux Falls
Porch

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.5 km from Sioux Empire Medical Museum
9.0 out of 10, Wonderful, (59 reviews)
"Property is very beautifully restored. The room was comfortable and cozy. The owner was very friendly and helpful. We will definately book again"
United States
Kathy
The price is ฿3,582
฿4,475 total
includes taxes & fees
12 Jul - 13 Jul
Historic Victorian Inn
Exterior

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.0 out of 10, Wonderful, (1,002 reviews)
"Great service and good breakfast. Facilities clean and quiet."
United States
Donald
The price is ฿4,126
฿4,593 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Exterior

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,003 reviews)
"Great location. "
United States
Kristin
The price is ฿4,047
฿5,004 total
includes taxes & fees
26 Jul - 27 Jul
Holiday Inn Sioux Falls-City Centre by IHG
Exterior

Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (1,305 reviews)
"Nice hotel great location"
United States
Mark
The price is ฿3,847
฿4,287 total
includes taxes & fees
12 Jul - 13 Jul
Country Inn & Suites by Radisson, Sioux Falls
Suite 2 Queens, Recliner, Pullout Sofa | Free WiFi, bed sheets

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (831 reviews)
"Great stsff Every thing was great"
United States
Jerold
The price is ฿3,163
฿3,536 total
includes taxes & fees
11 Jul - 12 Jul
The Center Inn
Lobby lounge

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay"
United States
Justin
The price is ฿4,356
฿4,845 total
includes taxes & fees
2 Aug - 3 Aug
Sheraton Sioux Falls Hotel & Convention Center
Basic Studio, 1 King Bed | Desk, free WiFi, wheelchair access

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,002 reviews)
"All was good I would stay there again."
United States
Larry
The price is ฿3,255
฿3,637 total
includes taxes & fees
8 Jul - 9 Jul
Valley Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,629 reviews)
"Everything was great pool and hot tub were perfect and the hotel was close to everything we needed."
United States
Cari
The price is ฿2,845
฿3,188 total
includes taxes & fees
12 Jul - 13 Jul
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
50-inch flat-screen TV with cable channels, fireplace, Netflix

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.4 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (3 reviews)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
The price is ฿8,432
฿9,580 total
includes taxes & fees
13 Jul - 14 Jul
Historic Twin Tudors Inn
Exterior

WoodSpring Suites Sioux Falls

WoodSpring Suites Sioux Falls
2.5 star property
2.8 km from Sioux Empire Medical Museum
5.6 out of 10, (87 reviews)
"Yes woodsprings is a nice living area.Its clean,staff is friendly.Its in a great location.Thank you Woodsprings for all you do..."
United States
Arie
The price is ฿2,621
฿2,941 total
includes taxes & fees
8 Jul - 9 Jul
WoodSpring Suites Sioux Falls
Lobby

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.6 out of 10, (1,004 reviews)
"It was a great stay."
United States
Shane
The price is ฿2,090
฿2,359 total
includes taxes & fees
8 Jul - 9 Jul
Ramada by Wyndham Sioux Falls
Terrace/patio

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.8 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,008 reviews)
"Great breakfast."
United States
Nicole
The price is ฿4,293
฿4,776 total
includes taxes & fees
21 Jul - 22 Jul
Hyatt Place Sioux Falls South
Property amenity

Staybridge Suites Sioux Falls by IHG

Staybridge Suites Sioux Falls by IHG
3.0 star property
Mall District, 3.2 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,005 reviews)
"Fantastic stay"
United States
Christina
The price is ฿4,160
฿4,630 total
includes taxes & fees
16 Jul - 17 Jul
Staybridge Suites Sioux Falls by IHG
Exterior

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 3.4 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (895 reviews)
"Clean facility comfortable beds and pillows. Late pool hours were a plus."
United States
Joyce
The price is ฿4,359
฿4,849 total
includes taxes & fees
26 Jul - 27 Jul
Holiday Inn & Suites Sioux Falls - Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Sioux Empire Medical Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains
Highpoint Hotel
3.0 star property
9.8
Exceptional
175 reviews
View
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4
Exceptional
654 reviews
View
Interior detail
Hotel On Phillips
2.5 star property
9.6
Exceptional
1,468 reviews
View
Exterior detail
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6
Exceptional
1,119 reviews
View
Meeting facility
Canopy By Hilton Sioux Falls Downtown
4.0 star property
9.4
Exceptional
227 reviews
View

Top Sioux Empire Medical Museum Hotel Reviews

La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

10/10 Excellent
"The hotel is clean, room was clean, comfortable beds. The breakfast had several hot and cold choices. We could take our dog and the room we were in didn’t have any pet odor from a previous pet. The hotel is so easy to find on I29and 41st St intersection. Would recommend for anyone needing a good place to stay for the price!"
Annette 2-night trip
Posted 4 hours ago
La Quinta Inn & Suites by Wyndham Sioux Falls

Hotels near other Sioux Empire Medical Museum attractions

University of Sioux Falls

8.0/10 (242 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 130 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Highpoint Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices close by include Valley Inn and Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 130 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Center for Western Studies and Delbridge Museum of Natural History feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Sherman Park, Falls Park or Fawick Park if you want a dose of fresh air.