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Our top choices for Santo Antonio hotels

Altis Grand Hotel

Altis Grand Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (1004)
"wonderful hotel and best service. "
United States
Jiemin
The price is ฿5,583
฿6,211 total
includes taxes & fees
8 Jan - 9 Jan 2026
Altis Grand Hotel

Eurostars Das Letras

Eurostars Das Letras
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1004)
"Friendly and helpful staff, great location in quiet neighbourhood, clean and well-appointed rooms."
Canada
Carolyn
The price is ฿3,698
฿4,212 total
includes taxes & fees
8 Jan - 9 Jan 2026
Eurostars Das Letras

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1001)
"We were lucky enough to stay at the hotel twice and found the staff really helpful the rooms spotless and the ambience terrific. "
United Kingdom
Peter
The price is ฿6,152
฿6,813 total
includes taxes & fees
30 Dec - 31 Dec
EPIC SANA Lisboa Hotel

Casa do Príncipe

Casa do Príncipe
4.0 star property
Lisbon City Center
8.8 out of 10, Excellent, (784)
Charming accommodation steps from Príncipe Real Stop with free WiFi and daily continental breakfast. Explore Rossio Square and Lisbon Cathedral within minutes, or stroll to Avenida da Liberdade. Guests consistently praise the helpful staff and prime location.

"An excellent B&B, location is close to many good restaurants and at a walking distance to downtown Lisbon, my room (Coronation Room) was overlooking the Botanical Garden and the rooftops of Lisbon, very quiet. Bathroom was modern, everything was spotless and well maintained. I had a great, relaxing stay."
United States
Thomas
Casa do Príncipe

PortoBay Marquês

PortoBay Marquês
4.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (1001)
"Great Location, very well maintained hotel, awesome breakfast and the best part, great staff and excellent service. Went for Anniversary celebrations, Hotel gifted sparkling wine for celebration, that was nice gesture. Overall great stay."
Canada
Sameer
The price is ฿3,274
฿3,763 total
includes taxes & fees
18 Jan - 19 Jan 2026
PortoBay Marquês

EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1296)
Elegant accommodation near Rossio Square offering Italian cuisine at ALLORA Restaurant. The full-service spa provides hot stone massages while two bars provide refreshment. Just 4 minutes from Parque Station and 7.5 km from the airport.

"The hotel is very elegant, incredibly clean. The staff is great and extremely helpful. Great location as well. Highly recommended."
United States
Paula
The price is ฿7,822
฿8,583 total
includes taxes & fees
29 Dec - 30 Dec
EPIC SANA Marques Hotel

Holiday Inn Express and Suites Lisbon Principe Real by IHG

Holiday Inn Express and Suites Lisbon Principe Real by IHG
3.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (51)
Immerse in Lisbon's culture with this centrally located hotel near Avenida da Liberdade. Just minutes from Marquis of Pombal Square and public transport, it offers free breakfast, WiFi, 2 bars, and a restaurant serving lunch and dinner.

"Location, staff, amenities, clean, spacious room, and amazing breakfast. "
United States
Tharmabahini
The price is ฿2,482
฿2,923 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express and Suites Lisbon Principe Real by IHG

EXE Liberdade

EXE Liberdade
3.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1002)
Immerse in Lisbon's charm at this centrally located hotel, just a 5-minute walk from Avenida da Liberdade and Marquis of Pombal Square. With 2 metro stations nearby, exploring attractions like Rossio Square becomes effortless.

"Very clean...staff very nice....parking on site...near many restaurants...really good breakfast. "
United States
Edward
The price is ฿2,140
฿2,561 total
includes taxes & fees
4 Jan - 5 Jan 2026
EXE Liberdade

Hotel Lisboa

Hotel Lisboa
4.0 star property
Lisbon City Center
8.8 out of 10, Excellent, (1000)
Centrally positioned in Lisbon, this hotel sits just steps from Avenida Station. Guests enjoy access to a fitness centre, on-site restaurant, and bar/lounge. Explore nearby attractions like Rossio Square while enjoying attentive service from the helpful staff.

"The hotel was excellent. Great location but most of all the staff were so helpful and very friendly. The staff made our holiday a great one. "
Canada
Katherine
The price is ฿2,140
฿2,561 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Lisboa

Browns Avenue Hotel

Browns Avenue Hotel
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (296)
" Breakfast was healthy and great quality foods, staff are a real asset to Brown hotel, super friendly and very nice, amazing service. Would definitely come back and highly recommend."
United States
Hassna
Browns Avenue Hotel

Pestana Lisboa Vintage City Center Suites

Pestana Lisboa Vintage City Center Suites
4.0 star property
Lisbon City Center
8.8 out of 10, Excellent, (568)
This elegant hotel sits just minutes from Marquis of Pombal Square and Marques de Pombal Station. Travellers praise the attentive staff and prime location, with Rossio Square and Santa Justa Lift a short drive away. Daily housekeeping ensures comfort throughout your stay.

"Nice stay "
United Kingdom
Bouillanne
The price is ฿3,015
฿3,488 total
includes taxes & fees
25 Jan - 26 Jan 2026
Pestana Lisboa Vintage City Center Suites

HF Fénix Music

HF Fénix Music
3.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (1003)
Stylish music-themed hotel in central Lisbon with a welcoming rooftop terrace and outdoor pool. Just 1 minute from Marques de Pombal Station, making Rossio Square easily accessible. Relax at the poolside bar after exploring the city.

"Clean room, friendly stuff, great breakfast"
United States
PIOTR
The price is ฿2,677
฿3,129 total
includes taxes & fees
11 Jan - 12 Jan 2026
HF Fénix Music

The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (326)
This luxury Lisbon hotel enchants with a rooftop terrace and full-service spa offering deep-tissue massages. Just steps from Avenida da Liberdade, guests enjoy an indoor pool, 2 bars, and Blue Bistrot dining. Rossio Square and excellent public transport are nearby.

"great holiday venue.great staff.great food"
United Kingdom
John
The Vintage Hotel & Spa - Lisbon

Legendary Lisboa Suites

Legendary Lisboa Suites
4.0 star property
Lisbon City Center
8.6 out of 10, Excellent, (765)
Unwind at this family-friendly aparthotel featuring poolside bar and kitchens in each apartment. Just 4 minutes from Rato Station and a short walk to Marquis of Pombal Square. Guests praise the attentive staff and convenient location near Rossio Square.

"Staff was very nice and helpful and room was very clean (WiFi was a bit spotty though)"
United States
Aibin
The price is ฿4,032
฿4,567 total
includes taxes & fees
19 Jan - 20 Jan 2026
Legendary Lisboa Suites

BessaHotel Liberdade

BessaHotel Liberdade
4.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1000)
Portuguese cuisine at Tabik restaurant and relaxing hot stone massages await at this centrally located hotel. Just minutes from Avenida da Liberdade with both indoor and outdoor pools for year-round swimming. Rossio Station is a 4-minute walk away.

"Great service and location! "
United Kingdom
Priscilla Bento e Silva de
The price is ฿4,922
฿5,509 total
includes taxes & fees
8 Jan - 9 Jan 2026
BessaHotel Liberdade

Hotel Britania Art Deco, a Lisbon Heritage Collection

Hotel Britania Art Deco, a Lisbon Heritage Collection
4.0 star property
Lisbon City Center
9.8 out of 10, Exceptional, (1003)
Located steps from Avenida da Liberdade, this quiet retreat offers 24-hour room service and a welcoming bar. Avenida Station is just 3 minutes away, making it easy to explore Rossio Square and other city sights with helpful staff recommendations.

"Great staff , room was amazing . Great location "
United Kingdom
James
The price is ฿4,838
฿5,421 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Britania Art Deco, a Lisbon Heritage Collection

Príncipe Real Guest House

Príncipe Real Guest House
3.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (71)
Walk to Avenida da Liberdade from this air-conditioned guesthouse with free WiFi. Explore Rossio Square just a short drive away or use nearby Rato Station for city adventures. Daily housekeeping ensures a comfortable, convenient stay in vibrant Lisbon.

"Enjoyed our stay!"
United States
Ashitha
Príncipe Real Guest House

Lisbon Serviced Apartments - Principe Real

Lisbon Serviced Apartments - Principe Real
4.0 star property
Lisbon City Center
8.4 out of 10, Very good, (264)
"Outstanding view, clean place, great walkability, very helpful service when we had difficulty checking in. "
United States
Valerie
The price is ฿2,370
฿2,805 total
includes taxes & fees
7 Jan - 8 Jan 2026
Lisbon Serviced Apartments - Principe Real

Industrial Lisbon Apartment - Adults Only

Industrial Lisbon Apartment - Adults Only
3.0 star property
Lisbon City Center
8.6 out of 10, Excellent, (31)
"Super location, great service, would definitely come back again!"
Canada
Sasha
The price is ฿2,045
฿2,460 total
includes taxes & fees
7 Jan - 8 Jan 2026
Industrial Lisbon Apartment - Adults Only

Mama Shelter Lisboa

Mama Shelter Lisboa
3.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (578)
Explore Lisbon from this vibrant hotel near Rato Station. Enjoy 2 restaurants, a stylish bar, and free WiFi while staying close to Marquis of Pombal Square. Just a short drive from Rossio Square and Santa Justa Lift.

"Great staff and amazing restaurant "
United States
REBECCA
The price is ฿3,076
฿3,553 total
includes taxes & fees
18 Jan - 19 Jan 2026
Mama Shelter Lisboa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in Santo Antonio

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Stay near popular Santo Antonio attractions

Learn more about Santo Antonio

Wander through the elegant Avenida da Liberdade, where luxury shops line a boulevard flanked by beautiful gardens and historic squares. Take in panoramic city views at Miradouro de São Pedro de Alcântara before exploring the fascinating collections at the Medeiros e Almeida Museum.

Santo Antonio showing heritage elements

Top Santo Antonio Hotel Reviews

More cheap stays in Santo Antonio

Frequently asked questions

What's the best place to stay in Santo Antonio?
Hotel das Amoreiras - Small Luxury Hotels of the World is ranked highly by Expedia customers. This hotel is a short 12-minute walk from Avenida da Liberdade, and it offers free breakfast and free WiFi. Reviews from our site also recommend Valverde Lisboa Hotel & Garden - Relais & Châteaux and Heritage Avenida Liberdade, a Lisbon Heritage Collection as top choices for your trip. See all available top hotels, or vacation rentals in Santo Antonio.
What are some of the best holiday rentals that Santo Antonio has to offer?
Villa dos Teixos: This holiday home rental outside of Santo Antonio is located next to a golf course, and has an outdoor pool, a balcony and a BBQ to put you at ease in your new surroundings. Kitchen amenities such as a stovetop and kitchenware can make your holiday run smoothly. It offers a terrace, a garden and a selection of games so that you can immerse yourself in your holiday. See all vacation rentals in Santo Antonio.
If I need to cancel my hotel reservation in Santo Antonio, will I receive a refund?
Yes, the majority of hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santo Antonio.
What's the best budget-friendly hotel in Santo Antonio?
Based on reviews, easyHotel Lisbon is a popular hotel for our travellers who want a more economical choice, and features free Wi-Fi and air conditioning. Other choices to stay on the cheap include Safestay Lisbon Bairro Alto and Lisboa Central Hostel. View all budget hotels in Santo Antonio.
What's the best family accommodation in Santo Antonio?
EPIC SANA Marques Hotel is a hotel with an outdoor pool and 2 restaurants, and it's a top choice on Expedia for families. Other choices for your stay with the children include Altis Grand Hotel and PortoBay Marquês. Also, children of all ages will enjoy a visit to National Museum of Natural History. Find more child-friendly accommodations in Santo Antonio.
What's the best LGBTQ-friendly accommodation in Santo Antonio?
Locke de Santa Joana is a top LGBTQ-friendly hotel, and features 2 restaurants and Smart TVs. EPIC SANA Marques Hotel and Mama Shelter Lisboa are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santo Antonio.
What's the best dog-friendly accommodation option in Santo Antonio?
Locke de Santa Joana is a top hotel for people travelling with their pets, and offers 2 restaurants and a seasonal outdoor pool for its human guests. Other good options for you and your pet include Pestana Lisboa Vintage City Center Suites and Mama Shelter Lisboa. See more pet-friendly hotel accommodations in Santo Antonio.
What's the best high-end place to stay in Santo Antonio?
EPIC SANA Marques Hotel is a luxury hotel with 2 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Altis Grand Hotel and Browns Avenue Hotel are two other upscale options for your stay. Find more luxury hotels in Santo Antonio.
What's the best boutique hotel in Santo Antonio?
Eurostars Das Letras is a favourite hotel with Expedia travellers looking for a stylish stay, and features a fitness centre and free WiFi. Hotel Britania Art Deco, a Lisbon Heritage Collection and Inspira Liberdade Boutique Hotel are other choices for a boutique stay. See all boutique hotels in Santo Antonio.
What are some accommodation options with pools in Santo Antonio?
EPIC SANA Marques Hotel is a top hotel with an indoor pool, an outdoor pool and 2 restaurants. A couple of other options that offer an on-site pool include Altis Grand Hotel and EPIC SANA Lisboa Hotel. View all hotels with pools in Santo Antonio.
What is the best spa hotel in Santo Antonio?
EPIC SANA Marques Hotel is a top luxury spa hotel featuring a rooftop terrace, a 24-hour fitness centre and an indoor pool. Enjoy a facial, body scrub or hot stone massage at SAYANNA WELLNESS & SPA. Other popular spa hotels in Santo Antonio include Altis Grand Hotel and EPIC SANA Lisboa Hotel. See all spa hotels in Santo Antonio.
What is staying in Santo Antonio like?
Luxury-minded travellers will find upscale places to stay in Santo Antonio, and visitors give high marks for the renowned art and relaxing spas. Welcoming and urban, this city also attracts tourists with its gardens. Top sights around the area include Avenida da Liberdade and Rossio Square. In Santo Antonio, there are 741 hotels and other accommodation options to choose from. Find out more about Santo Antonio.
What should I do while I'm visiting Santo Antonio?
Known for its art scene, cultural venues include Medeiros e Almeida Museum, Cinemateca Portuguesa Museum and National Museum of Natural History. Landmarks like Marquis of Pombal Square, São José and Coracao de Jesus might be worth a visit. Avenida da Liberdade is another notable sight to explore. Take a look at what more there is to see and do in Expedia's Santo Antonio guide.
How should I get around Santo Antonio?
Walk to nearby metro stations such as Avenida Station, Marques de Pombal Station and Rato Station. If you want to venture out around the area, you may want a rental car in Santo Antonio for your journey.
What's the seasonal weather in Santo Antonio?
The hottest months are usually August and July, with an average temperature of 21°C, while the coldest months are February and January, with an average of 13°C. Average annual precipitation for Santo Antonio is 573 mm.