Zona Colonial Travel Guide

Santa Fe de Antioquia

A historic fountain with water jets, surrounded by lush greenery and a white church with a bell tower in the background.
A street with buildings, a motorcycle, a tricycle, and a mountain in the background.
A vintage-themed living room with a large arched wall, a vintage camera, a red armchair, a wooden cabinet, and a large black and white portrait.
A colorful bus with 'La Santafrenia' written on it parked in front of a building with a tiled roof.
A white tuk-tuk parked on a cobblestone street in a historic town.

Stay near popular Zona Colonial attractions

Cathedral of Santa Fe de Antioquia

9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia when you stop by Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
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Things to do

Tour Santa Fe de Antioquia

Tour Santa Fe de Antioquia

฿5,008
per adult
Tour Santa Fe de Antioquia
Santa Fe de Antioquia: historical, theatrical, and gastronomic tour

Santa Fe de Antioquia: historical, theatrical, and gastronomic tour

฿3,530
per adult
Santa Fe de Antioquia: historical, theatrical, and gastronomic tour
Tour Santa Fe De Antioquia

Tour Santa Fe De Antioquia

฿8,180
per traveller
Tour Santa Fe De Antioquia
Rafting on the Dorado River, just 2 hours from Medellín, with rail transport

Rafting on the Dorado River, just 2 hours from Medellín, with rail transport

฿13,856
per traveller
Rafting on the Dorado River, just 2 hours from Medellín, with rail transport
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

฿4,941
per adult
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour
Private Vineyard Wine Spa and Vinotherapy Day Tour from Medellín

Private Vineyard Wine Spa and Vinotherapy Day Tour from Medellín

฿28,679
per adult
Private Vineyard Wine Spa and Vinotherapy Day Tour from Medellín
See all activities in Santa Fe de Antioquia

Top hotels in Zona Colonial

Hotel Mariscal Robledo

Hotel Mariscal Robledo

3 out of 5
Cra 12 No 9 70 Santa Fe de Antioquia Antioquia
The price is ฿3,862 per night from 25 Oct to 26 Oct
฿3,862
฿3,862 total
25 Oct - 26 Oct
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and room service. Popular attractions Cathedral of Santa Fe de Antioquia and Casa ...
Hotel Mariscal Robledo
Hotel Boutique Al Alma

Hotel Boutique Al Alma

4.5 out of 5
#9-50 Cra. 8 Santa Fe de Antioquia Antioquia
The price is ฿3,604 per night from 8 Nov to 9 Nov
฿3,604
฿3,604 total
8 Nov - 9 Nov
Stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free beach cabanas. Popular attractions Museo Juan del Corral and Bolivar ...
9.4/10 Exceptional! (67 reviews)
"Perfecto location , great staff, good food . Clean rooms ."

Reviewed on 22 Oct 2026

Hotel Boutique Al Alma
Entrecielos

Entrecielos

3 out of 5
Carrera 9 Santa Fe de Antioquia
The price is ฿2,532 per night from 25 Oct to 26 Oct
฿2,532
฿2,532 total
25 Oct - 26 Oct
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ...
9/10 Wonderful! (54 reviews)
"Muy bonito el lugar! Muy mala administración. Nos sentimos ignorados, nunca vimos a los dueños y administradores! Mal desayuno, un corrientes barato! Para empeorar las cosas, unos huéspedes borrachos que llegaron a las 3 de la mañana, nos despertaron a todos con su bulla y música rock a todo volumen; ..."

Reviewed on 27 Sept 2026

Entrecielos
Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años

Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años

3.5 out of 5
Calle 9 # 6- 37 Santa Fe de Antioquia Antioquia
The price is ฿5,577 per night from 26 Oct to 27 Oct
฿5,577
฿5,577 total
26 Oct - 27 Oct
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...
10/10 Exceptional! (63 reviews)
"Excelente atención y ubicación. Muy recomendable."

Reviewed on 20 Sept 2026

Casa Bixa Hotel Boutique -Santa Fe de Antioquia- Mayores de 12 años
Selva Maria Hotel Boutique

Selva Maria Hotel Boutique

3 out of 5
6-83 Cl. 10 Santa Fe de Antioquia Antioquia
The price is ฿2,360 per night from 25 Oct to 26 Oct
฿2,360
฿2,360 total
25 Oct - 26 Oct
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and daily housekeeping. Popular attractions Museo Juan del Corral and Bolivar Square ...
Selva Maria Hotel Boutique
Hotel Pueblito Viejo

Hotel Pueblito Viejo

3 out of 5
10-103 Cl. 10 Santa Fé de Antioquia Antioquia
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Popular attractions Cathedral of Santa Fe de Antioquia ...
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Hotel Pueblito Viejo
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Zona Colonial Travel Guide