Santa Cruz Packages (Flight + Hotel)

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
A tree-lined street with parked motorcycles and cars, and a person walking.

Historical Center

7 out of top 10 points of interest in this area

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

A courtyard with a curved building, columns, and a fountain.

El Arenal

Book a holiday in El Arenal to discover one of the most lively neighbourhoods in the Andalusian capital.

A bustling outdoor café area with people dining and walking.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

A riverside promenade with a bridge, historic buildings, and a calm river.

Triana

1 out of top 10 points of interest in this area

Get lost in the narrow lanes of the city’s old Roma quarter, known for its flamenco history and ceramics workshops.

A modern stadium with a unique curved roof structure, surrounded by urban buildings and a prominent tower in the background.

San Bartolomé

Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

Top hotels in Santa Cruz

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
฿6,053
฿6,658 total
10 Sept - 11 Sept
includes taxes & fees
9.2/10 Wonderful! (1,007 reviews)
"La beauté de l’hôtel qui ressemblait plus à une villa"

Reviewed on 3 Sept 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
฿23,896
฿26,285 total
13 Sept - 14 Sept
includes taxes & fees
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Fernando III

Hotel Fernando III

San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
฿7,570
฿8,327 total
8 Sept - 9 Sept
includes taxes & fees
Hotel Fernando III
See all 417 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz holiday package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or travelling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our holiday packages today.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organising your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
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A tall, ornate tower with intricate patterns and a statue on top, surrounded by historic buildings.

Giralda Tower

9.4/10 (6,353 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
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University of Seville

8.6/10 (1,316 reviews)
Explore the campus of University of Seville during your travels in Paseo de Las Delicias. Visit the stunning cathedral and shops in this culturally rich area.
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Santa Cruz Church

8.6/10 (26 reviews)
After visiting Santa Cruz Church, make a plan to see the other sights and activities in Seville. Visit the shops and top-notch restaurants in this romantic area.
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Murillo Gardens

9.2/10 (9 reviews)
Explore the great outdoors at Murillo Gardens, a lovely green space in Seville. Visit the shops and stunning cathedral in this romantic area.
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Santa María la Blanca Church

8.4/10 (8 reviews)
After visiting Santa María la Blanca Church, make a plan to see the other sights and activities in Seville. Visit the stunning cathedral and top-notch restaurants in this culturally rich area.
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General Archive of the Indies

8.0/10 (11 reviews)
You can study the exhibits at General Archive of the Indies, a museum with a story of its own, during your travels to Seville. Visit the stunning cathedral and lively bars in this culturally rich area.
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Casa del Flamenco Theater

9.0/10 (7 reviews)
Get tickets for a show at Casa del Flamenco Theater, a theatre with a story to tell in Seville. Visit the shops and stunning cathedral in this culturally rich area.
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Things to do

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

฿1,147
per adult
88% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
Landscape of Guadalquivir river area with several buildings in view.

Guadalquivir River Criuse Tour

฿722
per adult
80% of travellers recommend
Guadalquivir River Criuse Tour
Guided visit to Seville Fine Arts Museum

Fine Arts Museum of Seville Guided Tour with Tickets Included

฿688
per adult
Fine Arts Museum of Seville Guided Tour with Tickets Included
See all activities in Seville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.