Santa Cruz Packages (Flight + Hotel)
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ฿27,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
El Arenal
Book a holiday in El Arenal to discover one of the most lively neighbourhoods in the Andalusian capital.
Alfalfa
Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.
Triana
Get lost in the narrow lanes of the city’s old Roma quarter, known for its flamenco history and ceramics workshops.
San Bartolomé
Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Top hotels in Santa Cruz
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
฿5,078
฿5,586 total
22 Nov - 23 Nov
includes taxes & fees
9.2/10 Wonderful! (1,018 reviews)
"The bed was old with terrible mattress , heavy smell of disinfectant, the carpets were old and dirty"
Reviewed on 18 Oct 2026
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
฿22,762
฿25,038 total
15 Nov - 16 Nov
includes taxes & fees
Hotel Amadeus Sevilla
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
฿4,684
฿5,152 total
22 Nov - 23 Nov
includes taxes & fees
9.6/10 Exceptional! (1,291 reviews)
"Another trip to beautiful Sevilla and our first stay in Hotel Amadeus. Lovely architecture & stylish. Staff on check in were friendly & efficient and notified us as VIP Hotel.com guests that we had a drinks voucher. However later that night we receuc3d a notice from Hotel.com which inquired if we ..."
Reviewed on 22 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz holiday package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz holiday package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1,000,000 properties around the world. Whether you're enjoying a break with the whole family or travelling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our holiday packages today.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organising your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
Stay near popular Santa Cruz attractions
Royal Alcázar of Seville
9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
9.4/10 (6,353 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Triunfo Plaza
9.6/10 (18 reviews)
From this ancient and picturesque square, access some of the oldest and most impressive buildings in Seville, including the world’s largest gothic cathedral.
University of Seville
8.6/10 (1,316 reviews)
Explore the campus of University of Seville during your travels in Paseo de Las Delicias. Visit the stunning cathedral and shops in this culturally rich area.
Santa Cruz Church
8.6/10 (26 reviews)
After visiting Santa Cruz Church, make a plan to see the other sights and activities in Seville. Visit the shops and top-notch restaurants in this romantic area.
General Archive of the Indies
8.0/10 (11 reviews)
You can study the exhibits at General Archive of the Indies, a museum with a story of its own, during your travels to Seville. Visit the stunning cathedral and lively bars in this culturally rich area.
Puerta del Príncipe
10.0/10 (2 reviews)
Find out about the history of Seville when you take a trip to Puerta del Príncipe. Visit the stunning cathedral and lively bars in this culturally rich area.
Things to do
Guadalquivir River Criuse Tour
฿719
per adult
80% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
฿1,403
per adult
88% of travellers recommend
From Seville: Discover SETENIL & RONDA
฿1,864
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.