Search Holiday Rentals in Santa Cruz

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Top Holiday Rentals in Santa Cruz

Our top choices for Santa Cruz holiday rentals

Kukun Inspire Polanco

4.0 star property
9.2 out of 10, Wonderful, (129)
"Decent stay, clean rooms. "
The price is ฿3,276
฿3,964 total
includes taxes & fees
29 Sept - 30 Sept
Kukun Inspire Polanco

UTOPIC Polanco by ULIV

4.5 star property
9.0 out of 10, Wonderful, (619)
"It’s a good place to stay, specially if going for business purposes"
UTOPIC Polanco by ULIV

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (653)
"This ok, it's very nice, it's beautiful, "
The price is ฿1,372
฿1,660 total
includes taxes & fees
17 Sept - 18 Sept
Downtown Treasure Place

ULIV Parque Lincoln

3.5 star property
9.6 out of 10, Exceptional, (703)
"A nice place to stay "
ULIV Parque Lincoln

Las Suites Campos Eliseos

4.0 star property
9.2 out of 10, Wonderful, (1296)
"Great option close to many great places"
The price is ฿6,082
฿7,268 total
includes taxes & fees
20 Sept - 21 Sept
Las Suites Campos Eliseos

ULIV Antara

4.0 star property
9.4 out of 10, Exceptional, (219)
"I was very impressed with this hotel. It is located in a very good area with so many places to eat at walking distance. The location is excellent. The staff was extremely friendly and helpful. The place is extremely clean, and they provide an excellent service to all their guests. The room is very spacious and modern looking. I will highly recommend ULIV Antara to anyone traveling to Mexico City."
ULIV Antara

UTOPIC Platón by ULIV

5.0 star property
9.6 out of 10, Exceptional, (68)
"Excellent stay, highly recommend."
The price is ฿5,542
฿6,622 total
includes taxes & fees
1 Sept - 2 Sept
UTOPIC Platón by ULIV

Edgar Allan Poe 227 By Ömora

3.5 star property
10.0 out of 10, Exceptional, (27)
"Will definitely stay here again. Can’t say one bad thing about this place. "
The price is ฿2,844
฿3,399 total
includes taxes & fees
1 Sept - 2 Sept
Edgar Allan Poe 227 By Ömora

ULIV Apartments Polanco

4.0 star property
8.8 out of 10, Excellent, (251)
"Amazing stay would order next year again thank you for an amazing stay "
ULIV Apartments Polanco

Residence L'heritage Aristóteles 140 by Bluebay

3.5 star property
7.2 out of 10, Good, (371)
"Great Place to stay!!"
The price is ฿2,457
฿2,973 total
includes taxes & fees
1 Sept - 2 Sept
Residence L'heritage Aristóteles 140 by Bluebay

Capitalia Antara Polanco

4.5 star property
9.0 out of 10, Wonderful, (109)
"My stay was very enjoyable, and Karen at the front desk was exceptional!"
Capitalia Antara Polanco

Grand Polanco Residencial

4.0 star property
9.4 out of 10, Exceptional, (528)
"Very new and very nice accomodations in a beautiful building; staff was very friendly"
Grand Polanco Residencial

Hotel Monaco

3.5 star property
8.0 out of 10, Very good, (784)
"Great value for the master suite with great AC and in room hot tub. Great find in the historic district "
The price is ฿1,560
฿1,865 total
includes taxes & fees
10 Sept - 11 Sept
Hotel Monaco

The Wild Oscar

4.0 star property
9.6 out of 10, Exceptional, (455)
"This is a great hotel in a lovely location. Polanco is The place to stay in Mexico City. Great staff and welcoming environment. "
The price is ฿6,473
฿7,735 total
includes taxes & fees
1 Sept - 2 Sept
The Wild Oscar

Casa Sócrates by Kukun

2.0 star property
8.6 out of 10, Excellent, (124)
"Its' ok for one night, loud noise from the street "
Casa Sócrates by Kukun

Alteza Polanco

4.0 star property
8.6 out of 10, Excellent, (608)
"Nice little hotel. But they have a major deficiency-no king size beds"
Alteza Polanco

Ana Polanco Apartments

3.5 star property
9.8 out of 10, Exceptional, (151)
"Excellent place to stay, everything was perfect. Definitely will come back "
The price is ฿4,051
฿4,902 total
includes taxes & fees
1 Sept - 2 Sept
Ana Polanco Apartments

Capitalia Aristoteles Polanco

4.0 star property
9.0 out of 10, Wonderful, (80)
"I like the location"
Capitalia Aristoteles Polanco

Residence L´ Heritage Royal Colonial by BlueBay

3.0 star property
7.8 out of 10, Good, (240)
"If WiFi is important to you, this hotel is not for you. "
The price is ฿2,632
฿3,146 total
includes taxes & fees
8 Sept - 9 Sept
Residence L´ Heritage Royal Colonial by BlueBay

Park Life Masaryk

3.0 star property
9.2 out of 10, Wonderful, (474)
"We liked the staff at the front desk and the ability to interact with them personally with questions and advise on various topics. "
Park Life Masaryk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Are there holiday rentals in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Planetario Luis Enrique Erro, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the wider area.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies packed with people while still allowing you a great travel experience. You'll also have more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great choice for a family getaway.