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Check prices for these dates

In two weeks
9 Jan - 11 Jan
In two months
20 Feb - 22 Feb
In three months
20 Mar - 22 Mar
In four months
17 Apr - 19 Apr

Our top choices for Sant'Antonio holiday rentals

Exterior
Guest House All'83

Townhouse in Grosseto

Guest House All'83
9.6 out of 10, Exceptional, (5)
"Tutto ok!! Nessuna pecca!!"
Italy
Alessio
Guest House All'83
Exterior
Agriturismo Poggio Monte

Townhouse in Manciano

Agriturismo Poggio Monte
9.6 out of 10, Exceptional, (9)
" Great place and staff"
United States
Tomas
Agriturismo Poggio Monte
Comfort Quadruple Room | Free WiFi
Residence Il Boschetto

Townhouse in Grosseto

Residence Il Boschetto
9.0 out of 10, Wonderful, (6)
"The house is gorgeous! The area is very nice and the amenities were great! "
United States
Enrique
The price is ฿2,995
฿3,294 total
includes taxes & fees
7 Jan - 8 Jan 2026
Residence Il Boschetto
Deluxe Condo | Private kitchen | Full-sized fridge, microwave, stovetop, dishwasher
Corte Francigena

Apartment in Montalcino

Corte Francigena
9.8 out of 10, Exceptional, (6)
"Loved everything about my stay"
United States
Svetlana
The price is ฿5,211
฿6,171 total
includes taxes & fees
10 Jan - 11 Jan 2026
Corte Francigena
Double Room | Balcony
Il Cantuccio

Townhouse in Manciano

Il Cantuccio
9.2 out of 10, Wonderful, (53)
"very warm and welcoming. I do recommend having a phone with roaming access so you can receive your instructions to access."
Australia
Eugenio
Il Cantuccio
Massages
Chalet Il Cristallo

Townhouse in Castel del Piano

Chalet Il Cristallo
6.8 out of 10, (3)
"Puzza di chiuso e muffa in camera, muffa sul muro, letto con trapunta, lenzuolo e coprimaterasso con n macchia di non so cosa, per aprire lucernario del bagno ho dovuto togliere ragnatele con insetti incorporati. Molle del letto che si sentivano nella schiena e per finire nido sul davanzale che impediva la chiusura degli antoni, non avrei mai fatto togliere il nido amo gli animali, ma le tende interne oltre che sporche non si potevano tirare per impedire un po' alla luce di entrare, alle ore 5...
Italy
Giordano
The price is ฿2,096
฿2,416 total
includes taxes & fees
21 Jan - 22 Jan 2026
Chalet Il Cristallo
Exterior
La Dimora di Dida

Residence in Seggiano

La Dimora di Dida
The price is ฿2,496
฿2,745 total
includes taxes & fees
26 Dec - 27 Dec
La Dimora di Dida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sant'Antonio Hotel Reviews

Grand Hotel Impero - Wellness & Exclusive SPA

Grand Hotel Impero - Wellness & Exclusive SPA

10/10 Excellent
"This is a comfortable, clean hotel with the most gracious and helpful staff imaginable!"
Lynn 2-night trip
Posted 10 days ago
Grand Hotel Impero - Wellness & Exclusive SPA

Find out more about Sant'Antonio

Search for holiday rentals in Sant'Antonio on Expedia! You can easily find your home rentals, villas, holiday apartments in Sant'Antonio using one of the methods below:

  • View our selection of featured holiday rentals in Sant'Antonio
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  • Enter your travel dates to view the best deals on holiday rentals in Sant'Antonio while they last

Look no further and take a look at our great range of rental properties in Sant'Antonio!

Frequently asked questions

Can I find a holiday rental in Sant'Antonio?

Yes, there are holiday rentals close to the most popular sights in Sant'Antonio, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Sant'Antonio?

While exploring the area, visit family-friendly sights like Parco Piscine Capenti Outdoor Pool, or get outside and enjoy nature at Mount Amiata Fauna Park. Roselle Archaeological Area and Court of Grosseto are a couple of places you'll find in the wider area.

What’s a holiday rental in Sant'Antonio like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Sant'Antonio. Holiday rentals offer extras such as laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of safety away from shared hotel lifts and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular option for a family trip or a small group gathering.