
Puerto Santa Ana Packages (Flight + Hotel)
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ฿4,531 when you book a flight and hotel together*
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Where to stay in Puerto Santa Ana
Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana

Ecuador
Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.
Top hotels in Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ฿2,937 per night from 20 Feb to 21 Feb
฿2,937
฿3,309 total
20 Feb - 21 Feb
9.2/10 Wonderful! (1,007 reviews)
Staff was very friendly, food spectacular, and the infrastructure was amazing! Spa was a plus...
Reviewed on 5 Feb 2026

Luxury Suites Riverfront GYE
Puerto Santa Ana Guayaquil Guayas
The price is ฿3,436 per night from 27 Feb to 28 Feb
฿3,436
฿3,467 total
27 Feb - 28 Feb
9.2/10 Wonderful! (104 reviews)
La habitación estaba muy limpia excelente suite
Reviewed on 25 Jan 2026

River View suites Puerto Santa Ana gye
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ฿2,490 per night from 17 Feb to 18 Feb
฿2,490
฿2,521 total
17 Feb - 18 Feb
8.6/10 Excellent! (46 reviews)
Excellent
Reviewed on 15 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
Dr. Teodoro Maldonado Carbo Hospital
If Dr. Teodoro Maldonado Carbo Hospital is what brings you to town, hopefully you'll have a chance to explore more of Guayaquil.
Things to do

Half Day Walking Tour of Guayaquil Pearl of the Pacific
฿3,108
per adult

Guayaquil: Cloud Forest, Hiking & Canyoning Full Day Tour
฿13,332
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.




