Puerto Santa Ana Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿27,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Puerto Santa Ana
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Top hotels in Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ฿3,745 per night from 26 May to 27 May
฿3,745
฿4,201 total
26 May - 27 May
9.2/10 Wonderful! (1,002 reviews)
"After staying here several times, the food and service are great!"

Reviewed on 14 May 2026

Wyndham Guayaquil Puerto Santa Ana
River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye

3 out of 5
Puerto Santa Ana, Edificios Riverfront Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is ฿2,604 per night from 24 May to 25 May
฿2,604
฿2,637 total
24 May - 25 May
8.8/10 Excellent! (53 reviews)
"Beautiful apartment suite very safe close ally restaurant next a 24 pharmacy ac worked perfectly fine pool was beautiful and refreshing"

Reviewed on 23 Apr 2026

River View suites Puerto Santa Ana gye
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana Guayaquil Guayas
9.4/10 Exceptional! (107 reviews)
"Amazing stay. The apartment is beautiful, comfortable, and feels truly luxurious. .The location made everything even better. There’s a great market, pharmacy, and excellent restaurants just steps away. It made the whole stay very convenient, and I didn’t need to go anywhere else. Highly ..."

Reviewed on 16 Apr 2026

Get rates
Luxury Suites Riverfront GYE
See all 433 properties in Puerto Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Puerto Santa Ana holiday package cost?
You'll find cheap prices on Expedia for your Puerto Santa Ana break. However, a range of factors like your choice of hotel, the season and length of stay will influence how much your holiday to Puerto Santa Ana costs.
What are the cheapest months to go to Puerto Santa Ana?
The off-season is the best time to head to Puerto Santa Ana if you're on a budget. Another tip for finding cheap Puerto Santa Ana holiday packages? Avoid visiting during public holidays and any major festivals or events.
How many days is enough for Puerto Santa Ana?
Generally, a handful of days is enough to see the main attractions during your Puerto Santa Ana holiday. However, if you want to have more time to unwind or take day tours, consider extending your trip.
How to find the best Puerto Santa Ana package deals?
Use Expedia's filters to find some unbeatable Puerto Santa Ana package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or browse for Puerto Santa Ana package deals in the off-season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your holiday package well in advance.
Is it cheaper to book a Puerto Santa Ana holiday as a package?
Expedia holiday packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll typically get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalised Puerto Santa Ana holiday by choosing your preferred type of stay, airline and car class.
When to book a holiday package to Puerto Santa Ana?
Enjoy amazing discounts by booking your flights in advance with Expedia. If being spontaneous is more your style, snap up one of our last-minute deals for a spur-of-the-moment Puerto Santa Ana adventure.
How to plan a trip to Puerto Santa Ana?

  1. Pick the perfect time to travel: Your schedule, favourite season and the type of weather you like can all influence your decision on when to go to Puerto Santa Ana.
  2. Set a budget: Factor in expenses such as flights, meals and transportation when working out how much to put aside for your trip to Puerto Santa Ana. Then, pick a property that suits your budget, whether that's an affordable option or a lavish getaway.
  3. Decide your trip length: Consider how long you'd like to spend exploring Puerto Santa Ana. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Puerto Santa Ana holiday package that brings all your bookings together.

Things to do

Guayaquil: City Highlights Tour with Cable Car Ride

Guayaquil: City Highlights Tour with Cable Car Ride

฿3,768
per adult
Guayaquil: City Highlights Tour with Cable Car Ride
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

฿3,193
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

฿2,059
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.