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Check prices for these dates

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for Lake Nona Medical City hotels

Exterior

1. Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (458 reviews)
"nice clean hotel, close to restaurants"
United States
Ali
The price is ฿4,676
฿5,313 total
includes taxes & fees
8 Nov - 9 Nov
Aloft by Marriott Orlando Lake Nona
A swimming pool with sun loungers and palm trees.

2. Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (661 reviews)
"We had an amazing stay! Room was so nice and the perfect location! I dropped off balloons a day early to have in the room as a birthday surprise and the staff was so accommodating and nice! Shout out to Stephen who was great!"
United States
Christine
The price is ฿6,022
฿6,842 total
includes taxes & fees
18 Oct - 19 Oct
Courtyard Orlando Lake Nona
A swimming pool with sun loungers and palm trees, surrounded by a modern building.

3. Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (345 reviews)
"Great location. Would definitely stay again."
United States
Brooks
The price is ฿6,359
฿7,225 total
includes taxes & fees
11 Oct - 12 Oct
Residence Inn Orlando Lake Nona
A modern restaurant with multiple dining tables and chairs, a bar area, and a television mounted on the wall.

4. Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (4,278 reviews)
"Great place to overnight before a flight."
United States
Sheri
The price is ฿2,998
฿3,373 total
includes taxes & fees
12 Oct - 13 Oct
Wingate by Wyndham - Orlando International Airport
An outdoor patio area with seating, a bar, and a fire feature.

5. Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,886 reviews)
"Great staff, good breakfast and excellent location."
United States
Gerardo
The price is ฿3,970
฿4,466 total
includes taxes & fees
3 Nov - 4 Nov
Hyatt House Orlando Airport
A modern hotel room with a large bed, a nightstand, a drawer, a wall-mounted light, and a window with a view of trees.

6. Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very good, (6,154 reviews)
"Since last year I always look for this hotel the room are clean very good staff and good breakfast I recommend it to anyone."
United States
Sonia
The price is ฿2,831
฿3,185 total
includes taxes & fees
2 Nov - 3 Nov
Ramada by Wyndham Suites Orlando Airport
A modern lobby with a checkered carpet, seating area, and a reception desk.

7. Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,043 reviews)
"Wonderful stay! The staff were very accommodating and made us feel so comfortable. The breakfast was absolutely delicious and offered a great variety."
United States
Lorellie
The price is ฿3,260
฿3,668 total
includes taxes & fees
12 Oct - 13 Oct
Holiday Inn Express Orlando International Airport by IHG
An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

8. Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,885 reviews)
"So close to restaurants and the airport"
United States
Karen
The price is ฿3,403
฿3,829 total
includes taxes & fees
19 Oct - 20 Oct
Hampton Inn & Suites Orlando Airport @ Gateway Village
A modern hotel with a glass facade, palm trees, and a sign reading "DoubleTree by Hilton."

9. DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport
4.0 star property
Airport North, 11.2 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2,685 reviews)
"I thoroughly enjoyed my stay and would stay here again"
United States
Richard
The price is ฿3,283
฿3,693 total
includes taxes & fees
1 Nov - 2 Nov
DoubleTree by Hilton Orlando Airport
A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract artwork on the wall.

10. Hyatt Place Orlando Airport

Hyatt Place Orlando Airport
3.0 star property
Airport North, 11 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,931 reviews)
"I had a wonderful stay. Can't wait to go back."
United States
David Chad
The price is ฿3,398
฿3,823 total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Place Orlando Airport
A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

11. Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,993 reviews)
"Love the staff location and rooms, very convenient and comfortable!"
United States
Quintin
The price is ฿3,472
฿3,906 total
includes taxes & fees
1 Nov - 2 Nov
Cambria Hotel Orlando Airport
A modern dining area with a large table, chairs, and a coffee station.

12. avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,191 reviews)
"The staff were very helpful and clean surrounding, enjoyed my stay and will definitely stay there again"
Canada
Morgan
The price is ฿3,398
฿3,823 total
includes taxes & fees
2 Nov - 3 Nov
avid hotel Orlando International Airport by IHG
A spacious lobby with a wooden staircase, a reception desk, and a large wall clock.

13. Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL
3.0 star property
Airport North, 11 km from Lake Nona Medical City
7.8 out of 10, Good, (5,028 reviews)
"Great location at a great price!"
United States
Leonidas
The price is ฿2,602
฿2,927 total
includes taxes & fees
13 Oct - 14 Oct
Country Inn & Suites by Radisson, Orlando Airport, FL
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.

14. Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area
4.0 star property
22.9 km from Lake Nona Medical City
9.8 out of 10, Exceptional, (6,133 reviews)
"Always love staying here"
United States
Brianne
The price is ฿5,433
฿6,113 total
includes taxes & fees
28 Oct - 29 Oct
Drury Plaza Hotel Orlando - Disney Springs Area
A modern hotel with a red carpet leading to the entrance, a wooden walkway, and a clear view of the building's facade.

15. EVEN Hotel Orlando International Airport by IHG

EVEN Hotel Orlando International Airport by IHG
3.5 star property
Airport North, 11.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (916 reviews)
"Nice unique place to stay"
United States
Mykel
The price is ฿3,263
฿3,671 total
includes taxes & fees
12 Oct - 13 Oct
EVEN Hotel Orlando International Airport by IHG
A modern gym with treadmills, stationary bikes, and elliptical machines.

16. Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,177 reviews)
"Great stay will definitely stay again"
United States
Ian Robinson
The price is ฿2,960
฿3,330 total
includes taxes & fees
13 Oct - 14 Oct
Wyndham Garden Orlando Airport
A hotel with a prominent tower, palm trees, and a red roof.

17. La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.6 out of 10, Good, (2,808 reviews)
"Nice stay"
United States
Leza
The price is ฿2,545
฿2,863 total
includes taxes & fees
13 Oct - 14 Oct
La Quinta Inn & Suites by Wyndham Orlando Airport
A modern kitchen with wooden cabinets, a central island, and a breakfast bar.

18. Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport
2.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,197 reviews)
"Great stay"
United States
Roosevelt
The price is ฿3,260
฿3,668 total
includes taxes & fees
26 Oct - 27 Oct
Hampton Inn Orlando-International Airport
Room

19. Comfort Suites Orlando International Airport

Comfort Suites Orlando International Airport
2.5 star property
Belle Isle, 12 km from Lake Nona Medical City
8.4 out of 10, Very good, (1,358 reviews)
"Great place to stay"
United States
Sheryl
The price is ฿3,214
฿3,616 total
includes taxes & fees
12 Oct - 13 Oct
Comfort Suites Orlando International Airport
An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

20. Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (4,958 reviews)
"Nice clean rooms, the resort had everything."
United States
Maria
The price is ฿4,010
฿4,511 total
includes taxes & fees
18 Oct - 19 Oct
Rosen Shingle Creek
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in Lake Nona Medical City

Exterior

Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona
9.6 out of 10, Exceptional, (458)
The price is ฿4,676
฿5,313 total
includes taxes & fees
8 Nov - 9 Nov
Aloft by Marriott Orlando Lake Nona

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.
The entrance to the Hollywood Studios area with a large sign and distinctive architecture.
Photo by Gary Burke
Open Photo by Gary Burke

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

A large Ferris wheel with blue lights, surrounded by a cityscape with illuminated buildings and a tall green tower.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.
Photo by Peter Sutton
Open Photo by Peter Sutton

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Top Lake Nona Medical City Hotel Reviews

Universal's Endless Summer Resort - Dockside Inn and Suites

Universal's Endless Summer Resort - Dockside Inn and Suites

10/10 Excellent
"Simple yet very clean loved the shuttle"
scarlett 4-night trip
Posted 5 hours ago
Universal's Endless Summer Resort - Dockside Inn and Suites

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.