A riverside walkway with cyclists, a bridge, and modern buildings.

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Check availability on Greenville Spa Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Greenville hotels with a spa

A spa room with two beds, a mural, and a reception desk.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (570 reviews)
  • cleanliness
    Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
The price is ฿11,802
฿13,372 total
includes taxes & fees
22 Nov - 23 Nov
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

2. Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (875 reviews)
  • cleanliness
    Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
The price is ฿5,542
฿7,392 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.

3. Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (37 reviews)
  • cleanliness
    Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
The price is ฿14,129
฿15,542 total
includes taxes & fees
1 Nov - 2 Nov
Hotel Domestique
A wooden deck with chairs, surrounded by trees with autumn foliage.

4. The Orchard Inn

The Orchard Inn
3.0 star property
Saluda
9.4 out of 10, Exceptional, (142 reviews)
  • cleanliness
    Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
The price is ฿10,086
฿11,069 total
includes taxes & fees
1 Nov - 2 Nov
The Orchard Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

10/10 Excellent
"Great stay Friendly staff"
Ahmed 1-night trip
Posted 6 hours ago
La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
Hilton Greenville

Hilton Greenville

10/10 Excellent
"Location is great for getting to/from downtown area"
William 1-night trip
Posted 6 days ago
Hilton Greenville

Frequently asked questions

Looking to holiday at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travellers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness centre and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 702 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas which offer services including facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.