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Our top choices for Fresenius USA hotels

Free buffet breakfast
Staybridge Suites Lake Forest by IHG

Staybridge Suites Lake Forest by IHG

Staybridge Suites Lake Forest by IHG
3.0 star property
2.3 km from Fresenius USA
9.4 out of 10, Exceptional, (965)
"We loved the room it was beautiful and clean close to where we needed to go "
United States
Rhonda
The price is ฿3,735
฿4,115 total
includes taxes & fees
25 Jan - 26 Jan 2026
Staybridge Suites Lake Forest by IHG
Free breakfast
Holiday Inn Express & Suites Lake Forest by IHG

Holiday Inn Express & Suites Lake Forest by IHG

Holiday Inn Express & Suites Lake Forest by IHG
2.5 star property
2.4 km from Fresenius USA
9.0 out of 10, Wonderful, (648)
"Room is really clean, very spacious and checkin was great!"
United States
Norma
The price is ฿3,292
฿3,627 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Lake Forest by IHG
Outdoor pool
Residence Inn by Marriott Irvine Spectrum

Residence Inn by Marriott Irvine Spectrum

Residence Inn by Marriott Irvine Spectrum
3.0 star property
2.1 km from Fresenius USA
8.6 out of 10, Excellent, (374)
"Everyone was so nice! Our stay was very quiet! We will definitely stay here again. "
United States
Sharon
The price is ฿4,811
฿5,307 total
includes taxes & fees
9 Jan - 10 Jan 2026
Residence Inn by Marriott Irvine Spectrum
Exterior
Sonesta Simply Suites Irvine East Foothill

Sonesta Simply Suites Irvine East Foothill

Sonesta Simply Suites Irvine East Foothill
2.0 star property
0.6 km from Fresenius USA
8.4 out of 10, Very good, (1004)
"Staff is very friendly and rooms are clean"
United States
humberto
The price is ฿2,912
฿3,209 total
includes taxes & fees
18 Jan - 19 Jan 2026
Sonesta Simply Suites Irvine East Foothill
Lobby
Extended Stay America Suites Orange County Lake Forest

Extended Stay America Suites Orange County Lake Forest

Extended Stay America Suites Orange County Lake Forest
2.5 star property
3 km from Fresenius USA
5.8 out of 10, (1002)
"Kitchen was partially stocked. Parking was safe."
United States
Michael
The price is ฿2,706
฿2,982 total
includes taxes & fees
1 Jan - 2 Jan 2026
Extended Stay America Suites Orange County Lake Forest
Exterior
Homewood Suites by Hilton Irvine Spectrum Lake Forest

Homewood Suites by Hilton Irvine Spectrum Lake Forest

Homewood Suites by Hilton Irvine Spectrum Lake Forest
3.0 star property
4.4 km from Fresenius USA
9.2 out of 10, Wonderful, (835)
"Great facility and friendly staff"
United States
James
The price is ฿4,458
฿4,913 total
includes taxes & fees
30 Jan - 31 Jan 2026
Homewood Suites by Hilton Irvine Spectrum Lake Forest
Reception
Courtyard Irvine Spectrum

Courtyard Irvine Spectrum

Courtyard Irvine Spectrum
3.0 star property
5.2 km from Fresenius USA
9.4 out of 10, Exceptional, (1004)
"Everything is great, "
Canada
Reza
The price is ฿6,298
฿6,938 total
includes taxes & fees
31 Dec - 1 Jan 2026
Courtyard Irvine Spectrum
Lobby sitting area
Ayres Hotel Laguna Woods - Aliso Viejo

Ayres Hotel Laguna Woods - Aliso Viejo

Ayres Hotel Laguna Woods - Aliso Viejo
3.0 star property
6.7 km from Fresenius USA
9.4 out of 10, Exceptional, (1720)
"The breakfast was made to order, so Delicous and the staff was so friendly "
United States
Nancy
The price is ฿4,241
฿4,673 total
includes taxes & fees
4 Jan - 5 Jan 2026
Ayres Hotel Laguna Woods - Aliso Viejo
Outdoor pool, open 8:00 AM to 9:00 PM, pool umbrellas, pool loungers
Tiller House, Laguna Hills, A Tribute Portfolio Hotel

Tiller House, Laguna Hills, A Tribute Portfolio Hotel

Tiller House, Laguna Hills, A Tribute Portfolio Hotel
4.0 star property
4.8 km from Fresenius USA
9.2 out of 10, Wonderful, (35)
"Nicely decorated clean rooms … comfortable beds… Staff is terrific!!!!!"
United States
James
The price is ฿4,558
฿5,022 total
includes taxes & fees
25 Jan - 26 Jan 2026
Tiller House, Laguna Hills, A Tribute Portfolio Hotel
Lobby
Comfort Inn & Suites Irvine Spectrum

Comfort Inn & Suites Irvine Spectrum

Comfort Inn & Suites Irvine Spectrum
3.5 star property
4.4 km from Fresenius USA
9.0 out of 10, Wonderful, (1229)
"our stay has always been favorable, clean and accomodating"
United States
Helen
The price is ฿3,361
฿3,697 total
includes taxes & fees
25 Jan - 26 Jan 2026
Comfort Inn & Suites Irvine Spectrum
Garden
Laguna Hills Lodge

Laguna Hills Lodge

Laguna Hills Lodge
2.5 star property
5.6 km from Fresenius USA
9.0 out of 10, Wonderful, (2768)
"Awesome stay for Xmas :) Our third time staying here whenever visiting family. "
United States
Jane
Laguna Hills Lodge
Front of property – evening/night
Hilton Garden Inn Irvine Spectrum Lake Forest

Hilton Garden Inn Irvine Spectrum Lake Forest

Hilton Garden Inn Irvine Spectrum Lake Forest
3.5 star property
4.6 km from Fresenius USA
9.0 out of 10, Wonderful, (1199)
"Clean room, excellent staff"
United States
Tasha
The price is ฿4,077
฿4,492 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hilton Garden Inn Irvine Spectrum Lake Forest
Fridge, microwave, stovetop, dishwasher
TownePlace Suites by Marriott Irvine Lake Forest

TownePlace Suites by Marriott Irvine Lake Forest

TownePlace Suites by Marriott Irvine Lake Forest
3.0 star property
4.5 km from Fresenius USA
9.0 out of 10, Wonderful, (240)
"I treated my family member to stay here recently. I stay at this hotel several times a year myself and the reservation was made under my name. They recognized my name on her check in and they took the same special care of her during her stay. Thanks so much! "
United States
Nancy
The price is ฿4,008
฿4,417 total
includes taxes & fees
25 Jan - 26 Jan 2026
TownePlace Suites by Marriott Irvine Lake Forest
Outdoor pool, pool cabanas (surcharge), pool umbrellas
Marriott Irvine Spectrum

Marriott Irvine Spectrum

Marriott Irvine Spectrum
3.5 star property
5.1 km from Fresenius USA
9.0 out of 10, Wonderful, (1000)
"Very nice hotel! The lounges and convention area where my husband's Holiday Party was amazing! Our room was comfortable, clean and lovely. Oh, and the rooftop bar was happening!"
United States
Gina
The price is ฿7,248
฿8,628 total
includes taxes & fees
31 Dec - 1 Jan 2026
Marriott Irvine Spectrum
Desk, laptop workspace, blackout curtains, soundproofing
Hampton Inn by Hilton Irvine Spectrum/Lake Forest

Hampton Inn by Hilton Irvine Spectrum/Lake Forest

Hampton Inn by Hilton Irvine Spectrum/Lake Forest
3.0 star property
4.4 km from Fresenius USA
8.8 out of 10, Excellent, (1005)
"Hotel was very clean, staff were friendly and continental breakfast was wonderful. "
United States
Brittney
The price is ฿3,478
฿3,832 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn by Hilton Irvine Spectrum/Lake Forest
BBQ/picnic Area
Homewood Suites By Hilton Irvine John Wayne Airport

Homewood Suites By Hilton Irvine John Wayne Airport

Homewood Suites By Hilton Irvine John Wayne Airport
3.0 star property
15.2 km from Fresenius USA
9.6 out of 10, Exceptional, (1000)
"Excellent room and overall great condition of the hotel"
United States
carlos
The price is ฿5,503
฿6,064 total
includes taxes & fees
27 Jan - 28 Jan 2026
Homewood Suites By Hilton Irvine John Wayne Airport
Terrace/patio
Courtyard by Marriott Foothill Ranch Irvine East/Lake Forest

Courtyard by Marriott Foothill Ranch Irvine East/Lake Forest

Courtyard by Marriott Foothill Ranch Irvine East/Lake Forest
3.0 star property
3.9 km from Fresenius USA
9.0 out of 10, Wonderful, (1002)
"Great place to start with the family."
United States
Guadalupe
The price is ฿3,956
฿4,366 total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott Foothill Ranch Irvine East/Lake Forest
Reception
Ayres Suites Mission Viejo – Lake Forest

Ayres Suites Mission Viejo – Lake Forest

Ayres Suites Mission Viejo – Lake Forest
3.0 star property
6.2 km from Fresenius USA
9.2 out of 10, Wonderful, (1143)
"Great breakfast, friendly check in. "
United States
Erica
The price is ฿3,450
฿3,732 total
includes taxes & fees
4 Jan - 5 Jan 2026
Ayres Suites Mission Viejo – Lake Forest
Exterior
DoubleTree by Hilton Irvine - Spectrum

DoubleTree by Hilton Irvine - Spectrum

DoubleTree by Hilton Irvine - Spectrum
4.0 star property
5.7 km from Fresenius USA
8.8 out of 10, Excellent, (1011)
"Great stay!"
United States
William
The price is ฿4,464
฿4,910 total
includes taxes & fees
11 Jan - 12 Jan 2026
DoubleTree by Hilton Irvine - Spectrum
Terrace/patio
Laguna Surf

Laguna Surf

Laguna Surf
2.0 star property
15.9 km from Fresenius USA
9.6 out of 10, Exceptional, (22)
"Amazing place, right on the beach and offers so much. Would stay again. "
United States
Kristen
Laguna Surf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Fresenius USA Hotel Reviews

Sonesta Simply Suites Irvine East Foothill

Sonesta Simply Suites Irvine East Foothill

10/10 Excellent
"Staff is very friendly and rooms are clean"
humberto 1-night trip
Posted 4 days ago
Sonesta Simply Suites Irvine East Foothill
Residence Inn by Marriott Irvine Spectrum

Residence Inn by Marriott Irvine Spectrum

10/10 Excellent
"Excellent. "
Marcus 1-night trip
Posted 3 months ago
Residence Inn by Marriott Irvine Spectrum

Hotels near other Fresenius USA attractions

Heritage Hill Historic Park

4.3/5 (22 reviews)
After visiting Heritage Hill Historic Park, make a plan to see the other sights and activities in Lake Forest. Stroll along the area's beautiful beaches or simply savour its cosy cafes.
See properties

Arden-Modjeska Historic Site

4.2/5 (20 reviews)
Learn about the local history of Lake Forest when you spend time at Arden-Modjeska Historic Site. Wander the beautiful beaches or discover the area's beautiful sunsets.
See properties

Frequently asked questions

What's the area like around Fresenius USA?
Fresenius USA is located in Lake Forest. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 20 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Fresenius USA?
Sonesta Simply Suites Irvine East Foothill is one of the top choices for your stay based on our traveller data, and this hotel offers in-room kitchens and a fitness centre. It's located just a short 0.3 mi (0.6 km) from Fresenius USA. Another good option is Private Entry Suite w Patio Bath Kitchenette, located just 0.4 mi (0.6 km) away.
How many hotels should I expect to find near Fresenius USA?
Expedia has 20 hotels and other accommodation options within a mile from Fresenius USA.
If I need to cancel the hotel reservation for my stay near Fresenius USA, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the best options available near Fresenius USA.
What can I see and do near Fresenius USA?
Enjoy the outdoors at Orange County Great Park, Rancho Las Lomas or Heritage Hill Historic Park. Be sure to get some family photos at Great Park Carousel, Great Park Balloon and Giant Wheel at Irvine Spectrum Center while you're out sightseeing near Fresenius USA. Lake Mission Viejo, Arden-Modjeska Historic Site and Whiting Ranch Wilderness Park are beautiful places to appreciate nature.