Search Hotels in Downtown South San Francisco, San Francisco

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very good, (1,985 reviews)
"clean and close to the airport"
United States
William
The price is ฿3,171
฿3,727 total
includes taxes & fees
31 May - 1 Jun
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,001 reviews)
"We stayed overnight. The check-in process was quick and easy, and the room was spacious and comfortable. The bathroom was clean and functional, though nothing felt particularly special."
United States
ERIC
The price is ฿3,345
฿3,920 total
includes taxes & fees
17 May - 18 May
Airport Inn

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"Perfect for quick stays! Clean, safe and affordable! "
United States
carlos
The price is ฿2,855
฿3,358 total
includes taxes & fees
17 May - 18 May
Inn By The SFO

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.2 out of 10, Good, (17 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is ฿2,153
฿4,962 total
includes taxes & fees
17 May - 18 May
Miller Apartments

La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward
3.0 star property
26.3 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,242 reviews)
"This place was so good "
United States
Tae
The price is ฿2,816
฿3,272 total
includes taxes & fees
31 May - 1 Jun
La Quinta Inn & Suites by Wyndham Oakland - Hayward

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
27 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,191 reviews)
"great property and staff, will def come back!"
United States
Raymond
The price is ฿4,667
฿5,376 total
includes taxes & fees
24 May - 25 May
Hotel Shattuck Plaza

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG
2.5 star property
20.7 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,001 reviews)
"The friendliness of the staff and the ease of the airport shuttle were two highlights for me. The breakfast provided good too!"
United States
Mary
The price is ฿3,819
฿4,813 total
includes taxes & fees
28 May - 29 May
Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,431 reviews)
"Overall stay was good "
United States
Ganesh
The price is ฿3,100
฿3,534 total
includes taxes & fees
24 May - 25 May
The Marina Inn on San Francisco Bay

Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove
3.0 star property
20.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,009 reviews)
"Nice big hotel with a great breakfast and friendly staff. "
United States
Jonathan
The price is ฿4,425
฿5,142 total
includes taxes & fees
22 May - 23 May
Executive Inn & Suites Embarcadero Cove

Hampton Inn Oakland Downtown-City Center

Hampton Inn Oakland Downtown-City Center
2.5 star property
20.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
"Amazing staff and room. Breakfast was delicious and had so many options"
United States
Ana
The price is ฿3,949
฿4,589 total
includes taxes & fees
28 May - 29 May
Hampton Inn Oakland Downtown-City Center

Marina Village Inn

Marina Village Inn
2.0 star property
19.4 km from Downtown South San Francisco
7.4 out of 10, Good, (1,007 reviews)
"Recommend it for a vacation"
United States
Chengyang
The price is ฿3,267
฿3,724 total
includes taxes & fees
15 Jun - 16 Jun
Marina Village Inn

Hyatt Place Emeryville/San Francisco Bay Area

Hyatt Place Emeryville/San Francisco Bay Area
3.0 star property
22.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Clean rooms, and staff was great!"
United States
Beya
The price is ฿5,218
฿5,854 total
includes taxes & fees
29 May - 30 May
Hyatt Place Emeryville/San Francisco Bay Area

HYATT house Emeryville/San Francisco Bay Area

HYATT house Emeryville/San Francisco Bay Area
3.0 star property
23 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,308 reviews)
"Clean room, very good breakfast staff are very nice ."
United States
Ramzi
The price is ฿5,204
฿5,838 total
includes taxes & fees
26 May - 27 May
HYATT house Emeryville/San Francisco Bay Area

Sonesta Emeryville - San Francisco Bay Bridge

Sonesta Emeryville - San Francisco Bay Bridge
3.0 star property
22.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,444 reviews)
"Excellent Hotel."
United States
ed
The price is ฿4,019
฿4,872 total
includes taxes & fees
24 May - 25 May
Sonesta Emeryville - San Francisco Bay Bridge

Hampton Inn & Suites Oakland Airport-Alameda

Hampton Inn & Suites Oakland Airport-Alameda
2.5 star property
17.1 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay"
United States
Shukura
The price is ฿3,960
฿4,522 total
includes taxes & fees
31 May - 1 Jun
Hampton Inn & Suites Oakland Airport-Alameda

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
25.2 km from Downtown South San Francisco
8.2 out of 10, Very good, (4,606 reviews)
"Great location and friendly staff"
United States
Lynda Elaine
The price is ฿4,428
฿5,100 total
includes taxes & fees
24 May - 25 May
DoubleTree by Hilton Hotel Berkeley Marina

Atherton Park Inn & Suites

Atherton Park Inn & Suites
2.5 star property
27.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"It was comfortable and clean friendly staff"
United States
Adele
The price is ฿5,062
฿5,712 total
includes taxes & fees
25 May - 26 May
Atherton Park Inn & Suites

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
23.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,779 reviews)
"Great hotel at accessible prices "
United States
Emilio
The price is ฿3,208
฿3,624 total
includes taxes & fees
29 May - 30 May
Good Nite Inn - Redwood City

Grand Bay Hotel San Francisco

Grand Bay Hotel San Francisco
4.0 star property
20.2 km from Downtown South San Francisco
8.4 out of 10, Very good, (1,000 reviews)
"Clean room excellent staff really enjoyed my stay"
United States
Ana Patricia Rivera
The price is ฿3,085
฿4,981 total
includes taxes & fees
29 May - 30 May
Grand Bay Hotel San Francisco

Hyatt Regency San Francisco

Hyatt Regency San Francisco
4.0 star property
15.4 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (2,222 reviews)
"One of the best breakfast , great amenities, must experience. "
Canada
Ruchitha
The price is ฿6,432
฿9,056 total
includes taxes & fees
30 May - 31 May
Hyatt Regency San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Francisco Airport N is one of the top choices for your stay in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 11 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
South San Francisco Hillside Sign, Sign Hill Park and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.