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21 Oct - 22 Oct
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22 Oct - 23 Oct
This weekend
24 Oct - 26 Oct
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31 Oct - 2 Nov

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Top Trending Hotels Near Downtown South San Francisco, San Francisco

Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
8.0 out of 10, Very good, (2022)
"Great place to stay "
United States
Gladys
The price is ฿3,295
฿3,871 total
includes taxes & fees
2 Nov - 3 Nov
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Interior detail
Airport Inn
Airport Inn
2.0 star property
8.8 out of 10, Excellent, (965)
"I was surprised by how friendly the front desk guy was when I checked in after midnight, and also by how clean the room was, for the price I would say this is unbeatable for the area, I will be back."
United States
Todd
The price is ฿3,225
฿3,782 total
includes taxes & fees
24 Oct - 25 Oct
Airport Inn
Lobby
Inn By The SFO
Inn By The SFO
2.0 star property
7.8 out of 10, Good, (1006)
"Room is spacious"
Canada
leo
Inn By The SFO
Fridge, microwave, coffee/tea maker, dining tables
Miller Apartments
Miller Apartments
2.0 star property
7.4 out of 10, Good, (15)
"Ty"
United States
Mariah
The price is ฿2,036
฿4,847 total
includes taxes & fees
2 Nov - 3 Nov
Miller Apartments
Free daily buffet breakfast
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
9.0 out of 10, Wonderful, (2190)
"The stay was enjoyable and comfortable."
United States
Yanele
The price is ฿4,495
฿6,268 total
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Premium bedding, down duvets, in-room safe, desk
Harbor View Inn
Harbor View Inn
2.0 star property
9.0 out of 10, Wonderful, (590)
"This is a good well kept motel. The rooms are a good value. I would stay here again. "
United States
John
The price is ฿3,849
฿4,528 total
includes taxes & fees
29 Oct - 30 Oct
Harbor View Inn
Lobby
Hotel North Beach
Hotel North Beach
2.0 star property
7.0 out of 10, Good, (1010)
"Shops great food cool vibe this the coolest place love it "
United States
Sally
The price is ฿1,806
฿2,122 total
includes taxes & fees
30 Oct - 31 Oct
Hotel North Beach
Exterior
Half Moon Bay Lodge
Half Moon Bay Lodge
3.0 star property
9.0 out of 10, Wonderful, (1024)
"Great hotel"
United States
Yelena
The price is ฿4,550
฿5,341 total
includes taxes & fees
3 Nov - 4 Nov
Half Moon Bay Lodge
Terrace/patio
Hyatt Centric Fisherman's Wharf San Francisco
Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
8.6 out of 10, Excellent, (1452)
"Great place to stay."
United States
Christina
The price is ฿4,398
฿6,518 total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Centric Fisherman's Wharf San Francisco
Exterior
Hotel Caza Fisherman's Wharf
Hotel Caza Fisherman's Wharf
4.0 star property
9.0 out of 10, Wonderful, (3839)
"very nice place to stay"
United States
Holly J
The price is ฿4,661
฿6,981 total
includes taxes & fees
30 Oct - 31 Oct
Hotel Caza Fisherman's Wharf
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf
4.0 star property
9.0 out of 10, Wonderful, (7046)
"great breakfast would stay again"
United States
Sheila
The price is ฿3,501
฿5,462 total
includes taxes & fees
2 Nov - 3 Nov
Hotel Riu Plaza Fisherman's Wharf
Front of property
FOUND Hotel Carlton, Nob Hill
FOUND Hotel Carlton, Nob Hill
2.0 star property
8.6 out of 10, Excellent, (968)
"Place is amazing "
United States
Sarah
The price is ฿2,340
฿2,754 total
includes taxes & fees
3 Nov - 4 Nov
FOUND Hotel Carlton, Nob Hill
Front of property
The Lodge at Tiburon
The Lodge at Tiburon
3.5 star property
8.8 out of 10, Excellent, (1016)
"We enjoyed our stay "
United States
Xiaoyu
The price is ฿6,274
฿7,953 total
includes taxes & fees
26 Oct - 27 Oct
The Lodge at Tiburon
Outdoor pool
The Marina Inn on San Francisco Bay
The Marina Inn on San Francisco Bay
2.5 star property
8.6 out of 10, Excellent, (2183)
"We loved our rooms beautiful scenery, clean rooms great hospitality. "
United States
belinda
The price is ฿3,222
฿3,673 total
includes taxes & fees
22 Oct - 23 Oct
The Marina Inn on San Francisco Bay
Exterior
Hyatt Regency San Francisco Airport
Hyatt Regency San Francisco Airport
4.0 star property
8.8 out of 10, Excellent, (1341)
"beautifull place"
United States
Vivian
The price is ฿4,398
฿5,944 total
includes taxes & fees
9 Nov - 10 Nov
Hyatt Regency San Francisco Airport
Exterior
HYATT house Emeryville/San Francisco Bay Area
HYATT house Emeryville/San Francisco Bay Area
3.0 star property
9.0 out of 10, Wonderful, (1156)
"Great stay "
United States
Victoria
The price is ฿4,951
฿5,555 total
includes taxes & fees
30 Oct - 31 Oct
HYATT house Emeryville/San Francisco Bay Area
Iron/ironing board, free WiFi, bed sheets, alarm clocks
Hotel Focus SFO
Hotel Focus SFO
3.0 star property
7.6 out of 10, Good, (1480)
"Airport shuttle was convenient. The staff was really nice "
United States
Anthony
The price is ฿2,487
฿2,941 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Focus SFO
Front of property - evening/night
Hotel Nikko San Francisco
Hotel Nikko San Francisco
4.5 star property
9.4 out of 10, Exceptional, (2605)
"Convenient location. Great dining and sightseeing!"
Canada
Pamela
The price is ฿5,787
฿8,309 total
includes taxes & fees
21 Nov - 22 Nov
Hotel Nikko San Francisco
Exterior
SFO El Rancho Inn SureStay Collection by Best Western
SFO El Rancho Inn SureStay Collection by Best Western
3.0 star property
8.4 out of 10, Very good, (2905)
"Always a great stay when i'm here. "
United States
Afele
The price is ฿3,325
฿3,847 total
includes taxes & fees
23 Oct - 24 Oct
SFO El Rancho Inn SureStay Collection by Best Western
Front of property - evening/night
The Pickwick Hotel
The Pickwick Hotel
3.5 star property
7.8 out of 10, Good, (1014)
"Nice stay"
United States
Orlando
The price is ฿3,043
฿3,575 total
includes taxes & fees
8 Nov - 9 Nov
The Pickwick Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market which includes skyline, a park and cbd

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing street scenes and a city

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Downtown South San Francisco Hotel Reviews

Hyatt Regency San Francisco

Hyatt Regency San Francisco

10/10 Excellent
"Been to SF more than 10 times - usually stay around union square for Moscone - but honestly this is now my fav hotel, amazing design, very unique architecture. Rooms well maintained, clean and appointed and super friendly and helpful staff, nothing was a problem and everything I asked for sorted quickly and hassle free. This isnt always the case in SF. Bonus this part of town is without all the hassles and troubles you find further up in Union square and surrounds - the walk to Moscone wasnt bad and the hotel made it worth it. Definitely will be back here if I can. "
Michael 6-night trip
Posted 1 day ago
Hyatt Regency San Francisco

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.
What's a favourite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.
How many hotels should I expect to find in the Downtown South San Francisco area?
When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodation options in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.
What can I see and do in this South San Francisco neighbourhood?
See's Candies, Cinemark Century at Tanforan and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.