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Find hotels in Defiance, MO from ฿2,322

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Tonight
23 Oct - 24 Oct
Tomorrow
24 Oct - 25 Oct
This weekend
24 Oct - 26 Oct
Next weekend
31 Oct - 2 Nov

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Top 10 Defiance hotels and places to stay

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
8.0 out of 10, Very good, (1000)
"Clean room, friendly staff, good breakfast, hot tub and pool! Would stay again!"
United States
MARY
The price is ฿2,787
฿3,218 total
includes taxes & fees
2 Nov - 3 Nov
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel
The Wildwood Hotel
3.5 star property
9.2 out of 10, Wonderful, (1587)
"Perfect stay"
United States
Justin
The Wildwood Hotel
Front of property
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
8.0 out of 10, Very good, (1003)
"Clean room,Friendly staff, Good location and Good Breakfast options"
United States
Micheal
The price is ฿2,852
฿3,308 total
includes taxes & fees
30 Oct - 31 Oct
Sonesta ES Suites St. Louis - Chesterfield
Property amenity
Baymont by Wyndham Warrenton
Baymont by Wyndham Warrenton
2.5 star property
7.4 out of 10, Good, (1001)
"Very friendly staff. Nice place to stay"
United States
Bobby
The price is ฿2,803
฿3,216 total
includes taxes & fees
2 Nov - 3 Nov
Baymont by Wyndham Warrenton
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby
Super 8 by Wyndham Eureka/Six Flags Nearby
2.0 star property
7.0 out of 10, Good, (1017)
"Clean rooms fully stocked room with towels "
United States
Paul
The price is ฿1,993
฿2,322 total
includes taxes & fees
16 Nov - 17 Nov
Super 8 by Wyndham Eureka/Six Flags Nearby
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
9.4 out of 10, Exceptional, (812)
"Room and bathroom were very clean. Plenty of parking. And the breakfast was wonderful, plenty of options to choose from."
United States
Bryce
The price is ฿4,430
฿5,278 total
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby
Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
2.5 star property
8.0 out of 10, Very good, (1005)
"It was a very nice place"
United States
Jill
The price is ฿2,835
฿3,288 total
includes taxes & fees
17 Nov - 18 Nov
Best Western Plus St. Louis West-Westport
Lobby
Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles
2.0 star property
6.4 out of 10, (999)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
United States
Nikki
The price is ฿2,118
฿2,434 total
includes taxes & fees
26 Oct - 27 Oct
Days Inn by Wyndham St Peters/St Charles
1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds
Best Western Plus Washington Hotel
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (613)
"Would stay again. "
United States
Alisa
The price is ฿4,229
฿4,815 total
includes taxes & fees
26 Oct - 27 Oct
Best Western Plus Washington Hotel
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
8.8 out of 10, Excellent, (1001)
"Great hotel! "
United States
Jeffrey Frank
The price is ฿2,862
฿3,376 total
includes taxes & fees
27 Oct - 28 Oct
Sleep Inn & Suites O'Fallon MO - Technology Drive
Front of property – evening/night
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 star property
8.4 out of 10, Very good, (2187)
"Great stay would recommend "
United States
Ross
The price is ฿3,148
฿4,148 total
includes taxes & fees
9 Nov - 10 Nov
Hollywood Casino & Hotel St. Louis
Exterior
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
8.0 out of 10, Very good, (1001)
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
United States
Jean ss
The price is ฿3,134
฿3,601 total
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn St. Charles St. Peters
Lobby
AC Hotel by Marriott St. Louis Chesterfield
AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
9.2 out of 10, Wonderful, (211)
"Friendly staff, nice shower, good coffee"
United States
Bryan
The price is ฿4,167
฿4,834 total
includes taxes & fees
22 Nov - 23 Nov
AC Hotel by Marriott St. Louis Chesterfield
Exterior
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
3.0 star property
8.8 out of 10, Excellent, (1008)
"Staff was super friendly "
United States
Melissa
The price is ฿3,868
฿4,468 total
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Lobby
Super 8 by Wyndham Union
Super 8 by Wyndham Union
2.0 star property
8.2 out of 10, Very good, (624)
"All around great place to stay."
United States
Chris
The price is ฿2,537
฿2,803 total
includes taxes & fees
12 Nov - 13 Nov
Super 8 by Wyndham Union
Lobby
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.6 out of 10, Exceptional, (1002)
"Great staff and great amenities!"
United States
Alicia
The price is ฿3,347
฿3,879 total
includes taxes & fees
23 Nov - 24 Nov
Drury Plaza Hotel St. Louis St. Charles
Daily buffet breakfast (USD 12.95 per person)
Hilton Garden Inn Chesterfield
Hilton Garden Inn Chesterfield
3.0 star property
8.2 out of 10, Very good, (769)
"Very good room for the price"
United States
John
The price is ฿3,054
฿3,554 total
includes taxes & fees
2 Nov - 3 Nov
Hilton Garden Inn Chesterfield
Premium bedding, desk, iron/ironing board, free cots/infant beds
Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
8.0 out of 10, Very good, (1017)
"I'd stay at this place again. "
United States
Suzanne
The price is ฿2,480
฿2,850 total
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham St Charles
In-room safe, desk, laptop workspace, blackout curtains
Super 8 by Wyndham Warrenton
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (603)
"I have stayed several times at this hotel, it is always very clean, the staff are super nice and very convenient to I-70; would recommend this hotel and I will definitely stay there again."
United States
Kimberly
The price is ฿2,229
฿2,558 total
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham Warrenton
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
8.6 out of 10, Excellent, (805)
"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."
United States
Theresa
The price is ฿3,114
฿3,673 total
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
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Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
Bucsh Wildlife lakes are beautiful spots for sunrise or sunset.
Photo by Michael True
Open Photo by Michael True

Top Defiance Hotel Reviews

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent
"."
Mustafa 1-night trip
Posted 6 days ago
Wingate by Wyndham St. Louis/Fenton Route 66

More cheap stays in Defiance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive, St. Charles, MO
The price is ฿2,294 per night from 26 Oct to 27 Oct
฿2,294
฿2,660 total
26 Oct - 27 Oct
includes taxes & fees
5.6/10 (1,014 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Courtyard by Marriott St Louis Creve Coeur. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Drury Plaza Hotel St. Louis Creve Coeur and Hampton Inn St. Charles St. Peters are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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