Find hotels in Defiance, MO from ฿2,330
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Our top choices for Defiance hotels
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1,157 reviews)
"Everything was great for overnight stay. "
Regina
The price is ฿2,892
฿3,340 total
includes taxes & fees
29 Mar - 30 Mar
Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (954 reviews)
"Clean rooms, pleasant staff."
Karen
The price is ฿2,534
฿2,862 total
includes taxes & fees
9 Apr - 10 Apr
Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.6 out of 10, Good, (1,000 reviews)
"The front desk stuff were nice and welcoming. The room was clean and the breakfast was great. "
Dan
The price is ฿2,591
฿2,960 total
includes taxes & fees
2 Apr - 3 Apr
WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
9.0 out of 10, Wonderful, (59 reviews)
"Staff was very friendly "
Jessica
The price is ฿2,884
฿3,414 total
includes taxes & fees
28 Mar - 29 Mar
Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (635 reviews)
"The parking was easy, the room was verry clean."
Gary
The price is ฿1,763
฿2,013 total
includes taxes & fees
2 Apr - 3 Apr
Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
9.6 out of 10, Exceptional, (1,007 reviews)
"Very clean place with great food and friendly staff. "
Kara
The price is ฿3,726
฿4,358 total
includes taxes & fees
4 Apr - 5 Apr
Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (240 reviews)
"Friendly staff, clean room, quiet, nice amenities."
Catherine
The price is ฿3,213
฿3,711 total
includes taxes & fees
29 Mar - 30 Mar
Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
7.8 out of 10, Good, (1,168 reviews)
"Great location, comfy and clean rooms "
Nestor
The price is ฿2,754
฿3,180 total
includes taxes & fees
29 Mar - 30 Mar
The Wildwood Hotel
The Wildwood HotelWildwood
9.2 out of 10, Wonderful, (1,629 reviews)
"Staff was wonderful, location is great for our needs, and it was a quiet stay-which we loved. "
Jessica
Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (674 reviews)
"The room was clean and staff were nice. "
Rachel
The price is ฿3,862
฿4,420 total
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very good, (1,000 reviews)
"Great location and friendly staff
"
Heather
The price is ฿3,432
฿3,944 total
includes taxes & fees
5 Apr - 6 Apr
Quality Inn Near Six Flags St. Louis
Quality Inn Near Six Flags St. LouisPacific
8.4 out of 10, Very good, (366 reviews)
"Excellent staff & very clean room"
Karen
The price is ฿3,531
฿4,043 total
includes taxes & fees
26 Mar - 27 Mar
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
8.6 out of 10, Excellent, (887 reviews)
"It was a wonderful stay for my girls and her birthday. She had a blast and the room was Lovely 😍🌹"
Amanda
The price is ฿3,078
฿3,630 total
includes taxes & fees
5 Apr - 6 Apr
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very good, (1,002 reviews)
"Over all our stay was good. The room was a good size, we are thankful there was an ironing board and iron in the room. Good options at breakfast and the staff we encountered we are very pleasant. "
Elizabeth
The price is ฿3,178
฿3,653 total
includes taxes & fees
7 Apr - 8 Apr
Super 8 by Wyndham St Charles
Super 8 by Wyndham St CharlesSt. Charles
8.0 out of 10, Very good, (1,005 reviews)
"Hotel was clean. Located in a good area, would stay here again. "
Christy
The price is ฿2,726
฿3,133 total
includes taxes & fees
31 Mar - 1 Apr
Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,007 reviews)
"Great stay! Very clean and staff was very nice. Definitely will be staying there on my return visit to the area!"
Roxanne
The price is ฿3,564
฿4,096 total
includes taxes & fees
5 Apr - 6 Apr
River Sirens Hotel
River Sirens HotelWashington
9.8 out of 10, Exceptional, (191 reviews)
"The room was amazing!!! Would definitely stay again "
Katharine
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,000 reviews)
"Wonderful staff,very clean rooms!! Great breakfast and atmosphere. "
Sherri
The price is ฿2,653
฿3,130 total
includes taxes & fees
15 Apr - 16 Apr
Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'FallonO'Fallon
7.6 out of 10, Good, (1,004 reviews)
"Good spot and great location to visit with family "
Ernest
The price is ฿2,660
฿3,137 total
includes taxes & fees
19 Apr - 20 Apr
Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (665 reviews)
"Property was nice, easy check-in, nice breakfast, room was clean."
Doris
The price is ฿4,292
฿4,912 total
includes taxes & fees
29 Mar - 30 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
Top Defiance Hotel Reviews
Sonesta ES Suites St. Louis - Chesterfield
8/10 Good
More cheap stays in Defiance
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
The price is ฿2,093 per night from 29 Mar to 30 Mar
฿2,093
฿2,428 total
29 Mar - 30 Mar
includes taxes & fees
4.6/10 (1,007 reviews)
