A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
20 Nov - 22 Nov
In two months
1 Jan - 3 Jan
In three months
29 Jan - 31 Jan
In four months
26 Feb - 28 Feb

Our top choices for Defiance holiday rentals

A two-story house with a blue exterior, a front porch, and a small front yard.

1. Hickory Lake House

Hickory Lake House
3.0 star property
Wright City
The price is ฿9,368
฿14,706 total
includes taxes & fees
7 Nov - 8 Nov
Hickory Lake House
A spacious living area with a dining table, chairs, a sofa, and a fireplace. There is a kitchen area with a refrigerator, stove, and cabinets. The room has large windows and a ceiling fan.

2. Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
3.0 star property
St. Charles
10.0 out of 10, Exceptional, (4 reviews)
"The property was clean, easy to access, the property owner was easy to talk to and amazing. Loved staying there and will be staying again next year for the same bike race."
United States
Marina
Lovely Couples Escape on Mississippi River!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

The Wildwood Hotel

The Wildwood Hotel

10/10 Excellent
"My husband and I stayed here on our wedding night. We parked in the parking garage after checking in and were able to go right into the hallway near the elevators. The jacuzzi tub was amazing! I loved that they had towels specifically for makeup as well as a makeup wipe by the sink in the bathroom because I had forgotten to bring my own. The bed was so comfortable and you couldn’t hear other people in the hallway. The continental breakfast served what most hotels serve but everything tasted so much better! We are planning on staying again on our first anniversary!"
Philip 1-night trip
Posted 3 hours ago
The Wildwood Hotel

Find out more about Defiance

Search for holiday rentals in Defiance on Expedia! You can easily find your home rentals, villas, holiday apartments in Defiance using one of the methods below:

  • View our selection of featured holiday rentals in Defiance
  • Use the map to find apartments and other holiday homes in the Defiance neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Defiance while they last

Look no further and take a look at our great range of rental properties in Defiance!

Frequently asked questions

Can I find holiday rentals in Defiance?

Yes, there are holiday rentals close to the most popular sights in Defiance, or you can select a more secluded option if you're looking for a relaxing stay. Defiance is known for its wineries and parks.

How many holiday rentals will I find in Defiance?

With 3 Expedia holiday rentals, you're guaranteed to find just the right place for your Defiance stay.

What’s there to see and do in Defiance?

August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. Other places in town to visit include Yellow Farmhouse Winery and Chandler Hill Vineyards.

What’s a holiday rental in Defiance like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Defiance. Holiday rentals feature amenities such as hot tubs, fire pits and patios so you'll have everything you want. If you're concerned about a sanitised environment, holiday rentals can offer a sense of security away from shared hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a traditional hotel, which makes a holiday rental an attractive option for families.