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22 Dec - 23 Dec
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23 Dec - 24 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Casa Santo Domingo hotels

Traditional Villa, Non Smoking, Kitchenette | Living area | 32-inch Smart TV with digital channels
El Oasis Hotel

El Oasis Hotel

El Oasis Hotel
3.5 star property
17.1 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (116)
"My family and I stay at the "
United States
Joseph
The price is ฿2,566
฿2,797 total
includes taxes & fees
23 Dec - 24 Dec
El Oasis Hotel
Luxury Room | Frette Italian sheets, hypo-allergenic bedding, down duvets
Royal Isabela

Royal Isabela

Royal Isabela
4.5 star property
16 km from Casa Santo Domingo
9.6 out of 10, Exceptional, (163)
"Great resort! "
United States
Jodie
The price is ฿21,954
฿28,716 total
includes taxes & fees
5 Jan - 6 Jan 2026
Royal Isabela
Beach
Colinas del Atlantico for 18 People

Colinas del Atlantico for 18 People

Colinas del Atlantico for 18 People
3.5 star property
15.7 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (12)
"This property was spacious and great for our family of 14"
United States
Maria
The price is ฿6,219
฿12,352 total
includes taxes & fees
8 Jan - 9 Jan 2026
Colinas del Atlantico for 18 People
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hotel El Guajataca

Hotel El Guajataca

Hotel El Guajataca
3.5 star property
17 km from Casa Santo Domingo
8.4 out of 10, Very good, (1004)
"Wonderful sea view from every room. Nice personnel Excelent complementary breakfast The best view in the whole area Single deluxe room includes microwave and minifridge"
United States
Iris
Hotel El Guajataca
Beach
Colinas del Atlantico Vacational House 1st Floor

Colinas del Atlantico Vacational House 1st Floor

Colinas del Atlantico Vacational House 1st Floor
3.5 star property
15.7 km from Casa Santo Domingo
9.0 out of 10, Wonderful, (35)
"Very comfortable apartment (1st floor) will definitely rent again."
United States
Abimael
Colinas del Atlantico Vacational House 1st Floor
Porch
Hacienda Juanita

Hacienda Juanita

Hacienda Juanita
3.0 star property
18.2 km from Casa Santo Domingo
8.8 out of 10, Excellent, (525)
"Nice"
Canada
Keith
Hacienda Juanita
Deluxe Room, 1 Queen Bed | Down duvets, memory-foam beds, in-room safe, individually decorated
Luxury Puerto Caribe Boutique Hotel

Luxury Puerto Caribe Boutique Hotel

Luxury Puerto Caribe Boutique Hotel
3.5 star property
18.5 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (77)
"Love this place, the service, great room, the staff was amazing helpful and accommodating. "
United States
Janice
Luxury Puerto Caribe Boutique Hotel
2 outdoor pools
Hotel Vista Azul

Hotel Vista Azul

Hotel Vista Azul
3.0 star property
19.8 km from Casa Santo Domingo
9.0 out of 10, Wonderful, (20)
"Great property. Had lots to do. Only issue is parking as the club and other activities people park so hard for guests to park"
United States
Rose M
The price is ฿3,926
฿4,436 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Vista Azul
Luxury Condo | Private kitchen | Full-sized fridge, microwave, oven, stovetop
Jobos Luxury Condos

Jobos Luxury Condos

Jobos Luxury Condos
2.5 star property
18.7 km from Casa Santo Domingo
4.8 out of 10, (46)
"Loved it "
United States
Ingry N
The price is ฿3,957
฿4,234 total
includes taxes & fees
12 Jan - 13 Jan 2026
Jobos Luxury Condos
Property amenity
Golden Dream Studio 306 B

Golden Dream Studio 306 B

Golden Dream Studio 306 B
3.0 star property
17.8 km from Casa Santo Domingo
8.6 out of 10, Excellent, (24)
"This place was terrible, very unclean and bugs in the walls. Reached out to all numbers provided (phone, WhatsApp etc) to report the conditions of the place and did not receive a response. I do not recommend this place at all … terrible terrible unsanitary experience. The female security was the only good experience, she was very kind and respectful. "
United States
Alicia
The price is ฿2,374
฿5,937 total
includes taxes & fees
8 Jan - 9 Jan 2026
Golden Dream Studio 306 B
Beach nearby, beach shuttle, sun-loungers, beach umbrellas
Medusas Hostel

Medusas Hostel

Medusas Hostel
3.0 star property
18.5 km from Casa Santo Domingo
7.6 out of 10, Good, (98)
"Poor location, noisy, run-down lodging area."
United States
ALEXIS
The price is ฿2,261
฿2,936 total
includes taxes & fees
23 Dec - 24 Dec
Medusas Hostel
Outdoor pool
Villa Carmin I Apt with Private Pool

Villa Carmin I Apt with Private Pool

Villa Carmin I Apt with Private Pool
3.5 star property
16.2 km from Casa Santo Domingo
6.0 out of 10, (1)
"Muy bonita, limpia y acogedora. Lo único que le haría falta es calefacción a la picina. Llegamos a las 3pm y esa agua estaba de nevera, así q no pudimos usarla, pero ya que pagué obviamente porq tenía picina privada, al otro dia la usamos así d congelada, como 20 mins. porq de verdad estaba fría y hacía mucho viento, pero por lo demás, super bien. Buen trabajo al dueño del lugar. "
Mexico
Yashira
The price is ฿3,646
฿8,425 total
includes taxes & fees
23 Dec - 24 Dec
Villa Carmin I Apt with Private Pool
On the beach
Jobos Beach Apartment A-3

Jobos Beach Apartment A-3

Jobos Beach Apartment A-3
3.0 star property
18.7 km from Casa Santo Domingo
7.4 out of 10, Good, (20)
"Excellent location"
United States
Alberto
The price is ฿2,092
฿5,974 total
includes taxes & fees
8 Jan - 9 Jan 2026
Jobos Beach Apartment A-3
Rooftop terrace
Ache Pa Ti 1

Ache Pa Ti 1

Ache Pa Ti 1
3.5 star property
18.1 km from Casa Santo Domingo
The price is ฿2,544
฿7,224 total
includes taxes & fees
23 Dec - 24 Dec
Ache Pa Ti 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Casa Santo Domingo Hotel Reviews

Big vacational house in Isabela

Big vacational house in Isabela

10/10 Excellent
"Beautiful place! Loved my stay "
Keishla 1-night trip
Posted 6 months ago
Big vacational house in Isabela
Hotel Villas del Rey

Hotel Villas del Rey

8/10 Good
"The property were exactly what we expected, Carmen and crew were very nice, I really recommend this property, enjoyed."
Alvaro Rene Castillo 5-night trip
Posted 11 months ago
Hotel Villas del Rey

Hotels near other Casa Santo Domingo attractions

Guajataca State Forest

Commune with nature and explore the great outdoors at Guajataca State Forest during your travels in Isabela. Stroll along the beautiful beaches in this romantic area or visit its top-notch restaurants.
See properties

Aventuras Borinken

Commune with nature and explore the great outdoors at Aventuras Borinken during your travels in San Sebastian. Wander the beaches and seaside in this relaxing area.
See properties

Frequently asked questions

What's the area like around Casa Santo Domingo?
Casa Santo Domingo is located in an area of Guatemala that travellers like for its beaches. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Casa Santo Domingo?
Hotel Villas del Rey is one of the top choices for your stay based on our traveller data, and this hotel offers 15 outdoor pools and 2 restaurants. It's located just a short 0.4 mi (0.7 km) from Casa Santo Domingo. Other good options close by include Villas del Rey Hotel and San Sebastian Bed & Breakfast.
How many hotels are there close to Casa Santo Domingo?
Expedia has 5 hotels and other accommodation options within a mile from Casa Santo Domingo.
If I need to cancel the hotel reservation for my stay near Casa Santo Domingo, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available near Casa Santo Domingo.