The Best Hotels Closest to Buffalo Museum of Science in Buffalo - 2026 Updated Prices

A large mammoth skeleton in a museum with classical architecture.

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Our top choices for Buffalo Museum of Science hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A large, two-story building with a prominent entrance, multiple windows, and a well-maintained garden.

A grand room with a chandelier, a fireplace, and ornate furniture.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

1. InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

Terese

฿5,286

฿6,066 total

includes taxes & fees

5 Oct - 6 Oct

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

A historic building with a prominent tower and a traditional brick facade.

2. Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

John

฿10,938

฿12,719 total

includes taxes & fees

11 Oct - 12 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

3. The Edward Hotel

Elmwood Village, 2.4 km from Buffalo Museum of Science

Barbara

฿4,335

฿5,969 total

includes taxes & fees

1 Oct - 2 Oct

A two-story building with a white exterior, a red door, and large windows.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A hot tub with a wooden fence and a brick building in the background.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

4. Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

Jan

฿5,844

฿6,706 total

includes taxes & fees

1 Oct - 2 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A pool table in a room with patterned carpet, a dining table with chairs, and a red sofa.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

5. The Mansion On Delaware Ave

Allentown, 3 km from Buffalo Museum of Science

Marilyn

฿6,619

฿7,596 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with a bar area, seating, and a large TV screen.

A modern restaurant with a long counter, bar stools, and a refrigerated display.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a glass-enclosed area.

A modern hotel lobby with seating areas, a flat-screen TV, and a bookshelf.

6. Residence Inn by Marriott Buffalo Downtown

Allentown, 2.6 km from Buffalo Museum of Science

Karen

฿7,964

฿9,298 total

includes taxes & fees

14 Oct - 15 Oct

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

7. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 1.9 km from Buffalo Museum of Science

Amir

฿5,290

฿6,176 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

A modern kitchen with a central island, bar stools, and various appliances.

8. Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

John

฿5,108

฿5,964 total

includes taxes & fees

27 Oct - 28 Oct

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

A grand staircase with a decorative railing and a Christmas tree adorned with ornaments and ribbons.

A casino interior with slot machines, a large illuminated pillar, and comfortable seating areas.

A traditional living room with a wooden floor, a sofa, a coffee table, and a fireplace.

9. Summer Street Guest House

Bryant, 3 km from Buffalo Museum of Science

Anthony

฿12,060

฿17,693 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

A breakfast bar with a variety of food options including cereal, fruit, yogurt, eggs, and milk.

A gym with exercise equipment, a mirror, and a television.

10. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 3.1 km from Buffalo Museum of Science

Robert

฿4,402

฿5,139 total

includes taxes & fees

15 Oct - 16 Oct

A lobby with a staircase, seating area, and a view of the outdoors.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

11. Lenox Hotel and Suites

Allentown, 2.6 km from Buffalo Museum of Science

Anna Maria

฿3,402

฿3,904 total

includes taxes & fees

18 Oct - 19 Oct

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

12. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 3 km from Buffalo Museum of Science

Anthony T

฿5,887

฿6,873 total

includes taxes & fees

18 Oct - 19 Oct

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

A modern living room with a sectional sofa, a dining area, and a kitchen in the background.

13. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.4 km from Buffalo Museum of Science

฿9,974

฿17,669 total

includes taxes & fees

13 Oct - 14 Oct

A buffet setup with various food items and utensils.

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

14. Salvatores Grand Hotel

13.1 km from Buffalo Museum of Science

Margaret

฿5,676

฿6,456 total

includes taxes & fees

1 Oct - 2 Oct

A hotel with a prominent entrance, a clock tower, and the name "REIKART HOUSE" displayed above the entrance.

A spacious dining area with high ceilings, large windows, and modern chandeliers.

A spacious living area with a fireplace, a large sofa, and a dining area with a table and chairs.

15. Reikart House, Buffalo, a Tribute Portfolio Hotel

8.3 km from Buffalo Museum of Science

Brandon

฿9,039

฿10,282 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a large mirror.

16. Hampton Inn Buffalo - Amherst, NY

10.6 km from Buffalo Museum of Science

Warren

฿4,056

฿4,614 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with teal armchairs, a round table, a flat-screen TV, and a stone wall with a fireplace.

A modern lounge area with sofas, round tables, and a stone accent wall.

17. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

9 km from Buffalo Museum of Science

Randy

฿7,398

฿8,415 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A bar area with leather barstools, a bar counter, and a television screen.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

A multi-story hotel with a stone facade, a prominent entrance with a metal archway, and a parking lot in front.

18. The Delavan Hotel & Spa

12.4 km from Buffalo Museum of Science

Peter

฿3,251

฿3,698 total

includes taxes & fees

12 Oct - 13 Oct

A large indoor swimming pool with clear blue water, surrounded by lounge chairs and a sauna area.

A hotel lobby with a seating area featuring sofas, ottomans, and tables. A reception desk and a bar are visible in the background.

A modern hotel room with a large bed, a desk, a TV, and a view of the outdoors.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

19. Hampton Inn Buffalo-Williamsville

9.6 km from Buffalo Museum of Science

Robert

฿5,684

฿6,466 total

includes taxes & fees

12 Oct - 13 Oct

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern indoor space with a foosball table, seating areas, a mural, and a television screen.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

A modern lounge area with seating, tables, and hanging chairs.

20. Tru by Hilton Williamsville Buffalo Airport

13 km from Buffalo Museum of Science

Lachelle

฿4,256

฿4,841 total

includes taxes & fees

25 Oct - 26 Oct

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Compare popular hotels close to Buffalo Museum of Science

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 55 reviews	View
The Edward Hotel	9.6 Exceptional 264 reviews	View
Buffalo Guesthouse	9.4 Exceptional 213 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,009 reviews	View

Top Buffalo Museum of Science Hotel Reviews

M Hotel Buffalo

8/10 Good

"Nice property!! Very helpful staff"

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Friendly staff, excellent breakfast buffet, convenient location. I would definitely stay here again."

Wyndham Garden Buffalo Downtown

10/10 Excellent

"Great stay, great staff. Shuttle service available for local drop off and pickup."

Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent

"We were in room 1521, the bed was really soft, somewhat worn out, the bathroom was fine, it was very dark though-could use better lighting by the entry door-light was in the closet?"

Buffalo Guesthouse

8/10 Good

"The room was very clean and the staff was super helpful and accommodating. My biggest criticism here is that for the price I paid of almost $250 per night that it was definitely not worth it. The location was decent, but did not make up for the boarding room style rooms."

Best Western on the Avenue

8/10 Good

"Room was good , staff friendly Very helpful. Wood stay here again"

Lenox Hotel and Suites

8/10 Good

"the hotel was clean and staff were friendly"

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"L'emplacement est pratique, le quartier le soir a beaucoup d'itinérants comme partout ailleurs à Buffalo. Les fenêtres extérieures sont sales."

Summer Street Guest House

10/10 Excellent

"Loved the house, the owner, and his dog!"

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

You can find out about the history of Buffalo with a stop at Buffalo Central Terminal. Experience the entertainment choices and great live music in this vibrant area.

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Johnnie B. Wiley Sport Pavilion

Catch an event at Johnnie B. Wiley Sport Pavilion during your trip to Buffalo. Experience the area's entertainment choices and great live music.

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Paul Robeson Theater

Get tickets for a show at Paul Robeson Theater, a theatre with a story to tell in Buffalo. Experience the area's entertainment choices and great live music.

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African American Cultural Center

Enjoy a stop at African American Cultural Center, an entertaining place to visit in Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Broadway Market

You can browse for the perfect souvenirs at Broadway Market during your visit to Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Koessler Athletic Center

Catch an event at Koessler Athletic Center during your trip to Buffalo.

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Montante Cultural Center

Enjoy an outing to Montante Cultural Center during your stay in Buffalo.

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Hellenic Orthodox Church of the Annunciation

After visiting Hellenic Orthodox Church of the Annunciation, make a plan to see the other sights and activities in Buffalo.

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Frequently asked questions

What's the area like around Buffalo Museum of Science?

Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, take a look at the 14 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Buffalo Museum of Science?

Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. It's located 1.2 mi (1.9 km) from Buffalo Museum of Science. Other good choices within 5 miles include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find close to Buffalo Museum of Science?

Expedia has 14 hotels and other accommodation options within a mile from Buffalo Museum of Science.

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Yes, most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals near Buffalo Museum of Science.

What can I see and do near Buffalo Museum of Science?

Study the collections at Buffalo AKG Art Museum, Buffalo History Museum or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower and Richardson Olmsted Complex. You can watch performances at Kleinhans Music Hall, Town Ballroom and Road Less Traveled Productions if you're interested in local theatre.

Search Hotels Near Buffalo Museum of Science, Buffalo

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Our top choices for Buffalo Museum of Science hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Guesthouse

5. The Mansion On Delaware Ave

6. Residence Inn by Marriott Buffalo Downtown

7. Wyndham Garden Buffalo Downtown

8. Best Western on the Avenue

9. Summer Street Guest House

10. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

11. Lenox Hotel and Suites

12. Aloft by Marriott Buffalo Downtown

13. 4 Mi to Dtwn: Family Home in Buffalo

14. Salvatores Grand Hotel

15. Reikart House, Buffalo, a Tribute Portfolio Hotel

16. Hampton Inn Buffalo - Amherst, NY

17. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

18. The Delavan Hotel & Spa

19. Hampton Inn Buffalo-Williamsville

20. Tru by Hilton Williamsville Buffalo Airport

Compare popular hotels close to Buffalo Museum of Science

Top Buffalo Museum of Science Hotel Reviews

M Hotel Buffalo

Residence Inn by Marriott Buffalo Downtown

Wyndham Garden Buffalo Downtown

Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Guesthouse

Best Western on the Avenue

Lenox Hotel and Suites

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Summer Street Guest House

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

Johnnie B. Wiley Sport Pavilion

Paul Robeson Theater

African American Cultural Center

Broadway Market

Koessler Athletic Center

Montante Cultural Center

Hellenic Orthodox Church of the Annunciation

Frequently asked questions