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Our top choices for Southwest Coast Florida hotels

A modern hotel lobby with a reception desk, seating area, and a dining section.

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

฿3,805 total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio with a barbecue area, seating, and string lights.

2. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

฿4,637 total

includes taxes & fees

22 Nov - 23 Nov

A Drury Inn & Suites hotel with a parking lot full of cars.

3. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

฿4,812 total

includes taxes & fees

8 Nov - 9 Nov

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

4. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

฿2,877 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk, a chair, and a small table.

5. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Maria

฿3,326 total

includes taxes & fees

29 Nov - 30 Nov

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

6. Home2 Suites by Hilton Fort Myers Airport

Fort Myers

Donna

฿4,462 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

7. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Bibi

฿3,805 total

includes taxes & fees

29 Nov - 30 Nov

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

8. Hampton Inn Fort Myers Downtown

Fort Myers River District

Jason

฿4,257 total

includes taxes & fees

29 Nov - 30 Nov

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

9. Embassy Suites by Hilton Fort Myers Estero

Estero

Laura

฿4,808 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

10. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Erika

฿2,798 total

includes taxes & fees

30 Nov - 1 Dec

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

11. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

฿2,470 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Gabriel

฿3,760 total

includes taxes & fees

2 Nov - 3 Nov

A large, clear swimming pool with multiple lounge areas and palm trees.

13. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Anastasia

฿8,426 total

includes taxes & fees

1 Nov - 2 Nov

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

14. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

฿3,267 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with a stone fire pit, seating, and string lights.

15. SpringHill Suites by Marriott Fort Myers Estero

Estero

siobhan

฿4,703 total

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

16. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Julio

฿4,289 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

17. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

marleen

฿3,803 total

includes taxes & fees

8 Nov - 9 Nov

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

18. Pink Shell Beach Resort and Marina

Fort Myers Beach

Mario

฿10,283 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

19. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

฿2,573 total

includes taxes & fees

3 Nov - 4 Nov

A hotel with a covered entrance, palm trees, and a well-maintained garden.

20. Homewood Suites by Hilton - Fort Myers

Villas

Jose

฿4,123 total

includes taxes & fees

8 Nov - 9 Nov

View all properties

Holiday Rentals in Southwest Coast Florida

Aparthotel

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

Edison Beach House

Fort Myers Beach

"One of the best locations on Ft Myers Beach"

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Extremely clean, very easy check in. Everything is well maintained. Would definitely stay again."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Amazing place to stay when visiting Punta Gorda. Very convenient and loved having shops and restaurants so close by. Spacious unit - so much better than just a hotel room."

Condo

A beach with the sun setting over the ocean, creating a calm and serene atmosphere.

Lovers Key Resort 403 by Distinctive Beach Rentals

Fort Myers Beach

"Amazing views, quiet, and saw plenty of dolphins and manatees from the balcony!!!! Will be staying again soon! "

Apartment

A spacious living area with a curved ceiling, large windows, a dining area, and a kitchen.

Landing Furnished Apartments minutes from Downtown Fort Myers

Hancock

"Clean, quiet, perfect alternative to a hotel"

Villa

A beachside area with colorful beach houses, a dock, and a sandy beach.

Matlacha Tiny Village

Matlacha

"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

See properties

Learn more about Southwest Coast Florida

Amazing beaches, island views and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

Kompose Boutique Hotel

10/10 Excellent

"The rooms and entire hotel was spotless; staff was excellent and the breakfast was plentiful and good"

Sanibel Island Beach Resort

10/10 Excellent

"This was our first trip to Sanibel Island and and it did not disappoint! The rooms were clean. We had easy access to the beach, 2 minutes walk, the beach chairs were already on the beach and waiting. Everyone was so accommodating and friendly. It was such a relaxing atmosphere. The Tiki bar was amazing! Our bartender made us an old fashion and a strawberry daiquiri that was spot on. The on sight restaurant was fantastic. The burgers were delicious, but the fish and chips were good as well. Our breakfast was egg, ham and cheese bagel with a carmel and a mocha frappe... in one word it was delicious! The shelling was so much fun and was not a disappointment. We certainly will be returning!!"

Pink Shell Beach Resort and Marina

10/10 Excellent

"The complimentary breakfast was fantastic. The room was very clean. Probably one of the best places we have been in a while. We own at a resort in Ormond and it’s all about don’t do this, don’t do that… it’s a joy kill and this place is nothing like that. I was disappointed in the ocean itself. Water is a bit murky but the dolphin activity was incredible."

Spark by Hilton Sarasota Siesta Key Gateway

8/10 Good

"If I had known hot tub was not working, I would have not booked or stayed there. Chose this property because after a very long driving day, i just needed that soak! Speaking of soaking.... there are ZERO directions how to turn water on your goofy showers...so no water for me this stay, at all!"

More cheap stays in Southwest Coast Florida

Days Inn by Wyndham Bradenton I-75

644 67th Street Cir E Bradenton FL

฿1,674

฿1,891 total

1 Nov - 2 Nov

includes taxes & fees

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Our top choices for Southwest Coast Florida hotels

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

2. Homewood Suites by Hilton Fort Myers Airport/FGCU

3. Drury Inn & Suites Fort Myers Airport FGCU

4. Best Western Fort Myers Inn & Suites

5. SpringHill Suites by Marriott Fort Myers Airport

6. Home2 Suites by Hilton Fort Myers Airport

7. Hampton Inn & Suites Fort Myers - Colonial Blvd

8. Hampton Inn Fort Myers Downtown

9. Embassy Suites by Hilton Fort Myers Estero

10. Comfort Inn & Suites Fort Myers Airport

11. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

13. Margaritaville Beach Resort Fort Myers

14. Comfort Suites Fort Myers East I-75

15. SpringHill Suites by Marriott Fort Myers Estero

16. Home2 Suites by Hilton Fort Myers Colonial Blvd

17. Hampton Inn Fort Myers-Airport & I-75

18. Pink Shell Beach Resort and Marina

19. Extended Stay America Premier Suites - Fort Myers - Airport

20. Homewood Suites by Hilton - Fort Myers

Holiday Rentals in Southwest Coast Florida

Edison Beach House

Stay near popular Southwest Coast Florida attractions

Siesta Key Beach

Learn more about Southwest Coast Florida

Top Southwest Coast Florida Hotel Reviews

Kompose Boutique Hotel

More cheap stays in Southwest Coast Florida

Days Inn by Wyndham Bradenton I-75

Explore a world of travel with Expedia

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