A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito LGBT-friendly hotels

1. Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,198 reviews)
"We had a good stay! It’s a great location"
Canada
Heather
The price is ฿3,065
฿3,901 total
includes taxes & fees
30 Nov - 1 Dec
Palazzo Mannaioni Suites

2. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very good, (1,000 reviews)
"Conveniently located, easy parking, extremely friendly staff, delicious breakfast, quirky rooms."
Canada
Amy
The price is ฿2,873
฿3,689 total
includes taxes & fees
15 Nov - 16 Nov
UNA Hotels Vittoria Firenze

3. Soggiorno Alessandra

Soggiorno Alessandra
Santo Spirito
8.4 out of 10, Very good, (88 reviews)
"Alessandra is an amazing host, we had a perfect stay! The apartment is in excellent condition and very clean! "
United States
Elias
The price is ฿3,217
฿3,992 total
includes taxes & fees
8 Nov - 9 Nov
Soggiorno Alessandra

4. The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence
5.0 star property
Santa Maria Novella, 1 km from Santo Spirito
9.4 out of 10, Exceptional, (376 reviews)
"Great location, lovely staff, fab breakfast"
United Kingdom
faisal
The price is ฿17,540
฿19,899 total
includes taxes & fees
6 Dec - 7 Dec
The Excelsior, a Luxury Collection Hotel, Florence

5. Hotel Kraft

Hotel Kraft
4.0 star property
Porta al Prato, 1 km from Santo Spirito
9.4 out of 10, Exceptional, (680 reviews)
"We had an awesome 2 night stay! Beautiful, quiet location. Rooms are gorgeous. The rooftop bar and pool were another plus! Highly recommend."
United States
Sean
The price is ฿4,058
฿4,992 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Kraft

6. Grand Hotel Adriatico

Grand Hotel Adriatico
4.0 star property
Santa Maria Novella, 1.1 km from Santo Spirito
8.8 out of 10, Excellent, (1,001 reviews)
"Great location"
Canada
Dhara
The price is ฿3,979
฿4,905 total
includes taxes & fees
30 Nov - 1 Dec
Grand Hotel Adriatico

7. Grand Hotel Baglioni

Grand Hotel Baglioni
4.0 star property
Duomo, 1.5 km from Santo Spirito
9.0 out of 10, Wonderful, (1,004 reviews)
"Breakfast views are exceptional"
United States
Tannaz
The price is ฿4,496
฿5,474 total
includes taxes & fees
2 Dec - 3 Dec
Grand Hotel Baglioni

8. Bernini Palace

Bernini Palace
5.0 star property
Duomo, 1.8 km from Santo Spirito
9.8 out of 10, Exceptional, (1,002 reviews)
"Excellent place to stay."
United States
ALFONSO
The price is ฿10,640
฿12,308 total
includes taxes & fees
2 Dec - 3 Dec
Bernini Palace

9. 25hours Hotel Florence Piazza San Paolino

25hours Hotel Florence Piazza San Paolino
4.0 star property
Santa Maria Novella, 1.2 km from Santo Spirito
9.4 out of 10, Exceptional, (1,003 reviews)
"We have stayed here 3 times over the last few years and love the hotel. Conveniently located , close to the train station and wonderful staff"
United States
Timothy
The price is ฿5,644
฿6,737 total
includes taxes & fees
28 Nov - 29 Nov
25hours Hotel Florence Piazza San Paolino

10. Hotel Albani Firenze

Hotel Albani Firenze
4.0 star property
Santa Maria Novella, 1.6 km from Santo Spirito
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean hotel close to central train station and a short walk from most sights in the city."
Canada
Peter
The price is ฿3,986
฿4,913 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Albani Firenze

11. Mercure Firenze Centro

Mercure Firenze Centro
4.0 star property
Santa Maria Novella, 1.6 km from Santo Spirito
9.0 out of 10, Wonderful, (915 reviews)
"Fantastic hotel, some of the best views on the island!"
United States
Valon
The price is ฿4,634
฿5,626 total
includes taxes & fees
22 Nov - 23 Nov
Mercure Firenze Centro

12. Tornabuoni Suites Collection

Tornabuoni Suites Collection
Duomo, 1.4 km from Santo Spirito
9.6 out of 10, Exceptional, (352 reviews)
"Great location! Room was spacious and comfortable! Would stay again!"
United States
Bethany
The price is ฿5,411
฿7,162 total
includes taxes & fees
8 Nov - 9 Nov
Tornabuoni Suites Collection

13. Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA
5.0 star property
Porta al Prato, 1.3 km from Santo Spirito
9.2 out of 10, Wonderful, (79 reviews)
"The accommodation very much complimented our wonderful experience and love for Florence. Our room, the connected amenities and the wonderful attentive service made our trip very memorable."
Australia
Brett
The price is ฿6,198
฿7,422 total
includes taxes & fees
1 Dec - 2 Dec
Dimora Palanca Boutique & SPA

14. Hotel Boccaccio

Hotel Boccaccio
3.5 star property
Santa Maria Novella, 1.2 km from Santo Spirito
9.2 out of 10, Wonderful, (1,021 reviews)
"Great location, great staff,"
United Kingdom
robert
The price is ฿2,733
฿3,460 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Boccaccio

15. Gogò Petit Hotel

Gogò Petit Hotel
3.0 star property
Porta al Prato, 0.9 km from Santo Spirito
9.2 out of 10, Wonderful, (170 reviews)
"Great place"
Netherlands
Dennis
The price is ฿2,523
฿3,229 total
includes taxes & fees
2 Dec - 3 Dec
Gogò Petit Hotel

16. Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 1.1 km from Santo Spirito
9.6 out of 10, Exceptional, (216 reviews)
"Excellent location"
United States
Nancy
The price is ฿5,004
฿6,033 total
includes taxes & fees
19 Nov - 20 Nov
Leone Blu Suites | UNA Esperienze

17. Hotel Paris

Hotel Paris
3.0 star property
Duomo, 1.5 km from Santo Spirito
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location perfect for a quick stay and great walking distance to everything"
United States
Lauren
The price is ฿3,648
฿4,466 total
includes taxes & fees
17 Nov - 18 Nov
Hotel Paris

18. Numa Florence Felice

Numa Florence Felice
Historic Centre of Florence, 1 km from Santo Spirito
8.8 out of 10, Excellent, (52 reviews)
"The property was great. Everything was 10-15 minute walking distance. Lots of coffee shops and restaurants near by. The room itself was spacious compared to other rooms we've stayed in Italy."
United States
Jesus
The price is ฿5,807
฿6,841 total
includes taxes & fees
6 Dec - 7 Dec
Numa Florence Felice

19. Hotel Indigo Florence by IHG

Hotel Indigo Florence by IHG
4.0 star property
Santa Maria Novella, 1.4 km from Santo Spirito
9.2 out of 10, Wonderful, (227 reviews)
"A very unique, Hotel. The Staff was so helpful and answered any questions that we had."
Canada
Carol
The price is ฿4,016
฿4,946 total
includes taxes & fees
6 Dec - 7 Dec
Hotel Indigo Florence by IHG

20. IQ Hotel Firenze

IQ Hotel Firenze
4.0 star property
San Lorenzo, 2.5 km from Santo Spirito
9.6 out of 10, Exceptional, (1,281 reviews)
"Like everything about this hotel especially there breakfast. Also that they had a washer and dryer which made it very nice on our 26 days trip."
United States
Lin
The price is ฿3,700
฿4,599 total
includes taxes & fees
8 Nov - 9 Nov
IQ Hotel Firenze
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Spirito Hotel Reviews

Frequently asked questions

Searching for an LGBTQ-friendly hotel in Santo Spirito?
Whether you are travelling with your partner or flying solo, you'll find LGBTQ-friendly hotels in Santo Spirito on our website. The riverfront is something travellers enjoy about this welcoming area.
What's the best LGBTQ-friendly place to stay in Santo Spirito?
UNA Hotels Vittoria Firenze is a top LGBTQ-friendly hotel, and features free Wi-Fi and pillowtop beds. Soggiorno Alessandra is another good option for your holiday.
How many gay-friendly accommodation options will I find in Santo Spirito?
There are currently 2 LGBTQ-friendly hotels in Santo Spirito.
What should I do while I'm visiting Santo Spirito?
During your trip, get out and enjoy everything Santo Spirito has to offer. You and your travelling companions may want to visit Piazza Santo Spirito, Santo Spirito Basilica and Arno River. While you're here, create some great memories of your trip with stops at Torrigiani Garden, Piazza del Carmine and Brancacci Chapel.
What is a gay-friendly hotel in Santo Spirito?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. You'll find a selection of LGBTQ-friendly accommodation options on our site. In Santo Spirito, these hotels prioritise a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from LGBTQ-friendly accommodation in Santo Spirito?
Take a holiday from the ordinary; stay at a gay-friendly hotel in Santo Spirito, and you'll be around like-minded people, so you can relax and enjoy your trip. Many of our LGBTQ-friendly accommodation options offer concierge services that provide information about nearby LGBTQ restaurants and local events.