Search Hotels in Santa María, Oaxaca
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Our top choices for Santa María hotels
1. Holiday Inn Express Oaxaca-Centro Historico by IHG
Holiday Inn Express Oaxaca-Centro Historico by IHGRuta Independencia, 1.6 km from Santa María
9.6 out of 10, Exceptional, (1,006 reviews)
"Clean room excellent location"
Aivory
The price is ฿3,759
฿4,474 total
includes taxes & fees
16 Nov - 17 Nov
2. Hotel Victoria Oaxaca
Hotel Victoria Oaxaca0.8 km from Santa María
9.0 out of 10, Wonderful, (1,015 reviews)
"Great staff, the property could use an upgrade—or at least the room I was in. Carpet and furniture were older. Restaurant and staff there were outstanding."
Eugene
The price is ฿2,346
฿2,792 total
includes taxes & fees
22 Nov - 23 Nov
3. Hotel Trebol
Hotel TrebolOaxaca Centro, 2.1 km from Santa María
9.2 out of 10, Wonderful, (1,006 reviews)
"I loved this hotel it was in the perfect location everything was walkable. A little noisey as night but other than that recommend it highly would definitely stay there again!"
Norma
The price is ฿3,030
฿3,605 total
includes taxes & fees
10 Nov - 11 Nov
4. Hotel Boutique Naura Centro
Hotel Boutique Naura CentroOaxaca Centro, 2.2 km from Santa María
9.4 out of 10, Exceptional, (1,014 reviews)
"Great location and nice room, staff were mostly helpful"
George
The price is ฿4,829
฿5,747 total
includes taxes & fees
12 Nov - 13 Nov
5. Quinta Real Oaxaca
Quinta Real OaxacaRuta Independencia, 1.9 km from Santa María
9.6 out of 10, Exceptional, (1,002 reviews)
"Great hotel if you like old world charm."
William
The price is ฿10,782
฿12,831 total
includes taxes & fees
3 Dec - 4 Dec
6. Hotel Abu
Hotel AbuRuta Independencia, 1.9 km from Santa María
8.6 out of 10, Excellent, (594 reviews)
"The rooms were very clean the location was perfect! The staff were very nice and helpful. Their breakfast was really good and variety every day, Jose Luis and Michelle were always so nice and always so polite. Thank you will definitely stay here again!"
Patricia
The price is ฿3,104
฿3,693 total
includes taxes & fees
10 Nov - 11 Nov
7. Hotel Casa del Sótano
Hotel Casa del SótanoRuta Independencia, 1.5 km from Santa María
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was great"
Oscar
The price is ฿2,726
฿3,244 total
includes taxes & fees
5 Dec - 6 Dec
8. One Oaxaca Centro Hotel
One Oaxaca Centro HotelRuta Independencia, 2.5 km from Santa María
8.8 out of 10, Excellent, (1,004 reviews)
"Clean room, close to restaurant"
Jorge
The price is ฿3,021
฿3,595 total
includes taxes & fees
16 Nov - 17 Nov
9. Happy Express Hotel
Happy Express HotelOaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (413 reviews)
"Great affordable location walkable to the shopping and historic area."
Ed
The price is ฿1,665
฿1,981 total
includes taxes & fees
10 Nov - 11 Nov
10. City Express by Marriott Oaxaca
City Express by Marriott OaxacaRuta Independencia, 1.3 km from Santa María
8.6 out of 10, Excellent, (870 reviews)
"My sisters, cousins and I stayed here in August 2026 for a girls trip and had a wonderful experience. A huge highlight was the breakfast buffet which was fresh and had plenty of options. The location is perfect a few minutes from Downtown and surrounded by good local restaurants."
Cristina
The price is ฿3,033
฿3,609 total
includes taxes & fees
22 Nov - 23 Nov
11. El Callejón Hotel Boutique
El Callejón Hotel BoutiqueRuta Independencia, 1.5 km from Santa María
9.8 out of 10, Exceptional, (222 reviews)
"What a wonderful place to stay. Everybody is so attentive, kind, and empathetic, and we had the best time. They even arranged for a mariachi for my wife on her birthday and added special items to the room. First class amazing people, thank you so much."
Michael
The price is ฿12,652
฿15,056 total
includes taxes & fees
14 Nov - 15 Nov
12. Hotel Fortin Plaza
Hotel Fortin Plaza1 km from Santa María
8.8 out of 10, Excellent, (1,003 reviews)
"Good place to stay in Oaxaca will book again"
Sal
The price is ฿2,683
฿3,193 total
includes taxes & fees
8 Dec - 9 Dec
13. Hotel Real Alma
Hotel Real AlmaOaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (564 reviews)
"Very good location; Friendly staff, Good breakfast.
I traveled with my mother of 93 years and the problem was that she had to climb a step to use the bathroom."
Martha
The price is ฿2,357
฿2,805 total
includes taxes & fees
8 Dec - 9 Dec
14. Hotel Casa Conzatti
Hotel Casa ConzattiRuta Independencia, 1.7 km from Santa María
9.0 out of 10, Wonderful, (242 reviews)
"Location; friendliness of staff; nice decor."
Nancy
The price is ฿3,065
฿3,648 total
includes taxes & fees
10 Nov - 11 Nov
15. Hotel con Corazón Oaxaca
Hotel con Corazón OaxacaCalzada Madero, 1.3 km from Santa María
9.6 out of 10, Exceptional, (391 reviews)
"Wonderful breakfast every day."
Theodore
The price is ฿2,650
฿3,154 total
includes taxes & fees
12 Nov - 13 Nov
16. Casa Los Cantaros Hotel Boutique
Casa Los Cantaros Hotel BoutiqueReforma, 1.8 km from Santa María
9.4 out of 10, Exceptional, (332 reviews)
"The rooms are clean and comfortable, and the staff is so helpful"
Sol Nivania
The price is ฿2,846
฿3,387 total
includes taxes & fees
29 Nov - 30 Nov
17. Hotel Oaxaca Real
Hotel Oaxaca RealRuta Independencia, 1.7 km from Santa María
8.6 out of 10, Excellent, (1,002 reviews)
"Great location, friendly staff!"
Cheyenne
The price is ฿2,462
฿2,929 total
includes taxes & fees
10 Dec - 11 Dec
18. HOTEL POSADA DON MATIAS
HOTEL POSADA DON MATIASOaxaca Centro, 2 km from Santa María
8.8 out of 10, Excellent, (468 reviews)
"Great location"
Elvis
The price is ฿1,044
฿1,242 total
includes taxes & fees
10 Nov - 11 Nov
19. Hotel Danibaan
Hotel DanibaanDel Ex-marquezado, 1.1 km from Santa María
9.4 out of 10, Exceptional, (219 reviews)
"Excelente hotel "
Alejandra
The price is ฿1,661
฿1,977 total
includes taxes & fees
16 Nov - 17 Nov
20. City Centro by Marriott Oaxaca
City Centro by Marriott OaxacaJalatlaco, 2.4 km from Santa María
9.0 out of 10, Wonderful, (859 reviews)
"The property was lovely and very clean."
Maria Angelica
The price is ฿5,610
฿6,676 total
includes taxes & fees
1 Dec - 2 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Santa María
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Holiday Inn Express Oaxaca-Centro Historico by IHG | 9.6 Exceptional 1,006 reviews | View | ||||||
 Hotel Victoria Oaxaca | 9.0 Wonderful 1,015 reviews | View | ||||||
 Quinta Real Oaxaca | 9.6 Exceptional 1,002 reviews | View | ||||||
 One Oaxaca Centro Hotel | 8.8 Excellent 1,004 reviews | View | ||||||
 Hotel Ayook | 9.8 Exceptional 198 reviews | View |
Where to stay in Santa María
Find the best Santa María areas for the activities you enjoy most.
Photo by Julie Ruth
Open Photo by Julie Ruth
Oaxaca Centro
Churches, museums and art galleries are some highlights of Oaxaca Centro. Make a stop by Oaxaca Textile Museum or Oaxaca Cathedral while you're exploring.
Photo by Sergio Camalich
Open Photo by Sergio Camalich
Ruta Independencia
While visiting Ruta Independencia, you might make a stop by sights like Oaxaca Ethnobotanical Garden and Jardín Etnobotánico.
Jalatlaco
While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.
Photo by Tahino2000
Open Photo by Tahino2000
Reforma
While visiting Reforma, you might make a stop by sights like Plaza Parque and Plaza Mazari.
Photo by Rodrigo López
Open Photo by Rodrigo López
Santa Cruz Xoxocotlán
Archaeological sites and cafes are just a few things travellers like about Santa Cruz Xoxocotlán. A stop by Monte Albán is also recommended if you've got time to explore the area.
