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Check prices for these dates

Tonight
14 Dec - 15 Dec
Tomorrow
15 Dec - 16 Dec
Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec

Our top choices for Santa Lucia holiday rentals

Exterior detail
hu Roma Camping In Town

Camping in Gianicolense Suburb

hu Roma Camping In Town
8.2 out of 10, Very good, (2395)
"Excellent staff & accommodations "
Canada
Luigi
The price is ฿1,626
฿2,011 total
includes taxes & fees
9 Jan - 10 Jan 2026
hu Roma Camping In Town
Exterior
Aldrovandi Residence City Suites

Aparthotel in Pinciano

Aldrovandi Residence City Suites
4.0 star property
8.8 out of 10, Excellent, (1241)
"We enjoyed our breakfasts before long and dense days in Rome museums. Good transport choices to get around Rome. Very friendly staff. Will definitely stay next time in this hotel."
United States
Tatiana
The price is ฿3,480
฿4,272 total
includes taxes & fees
15 Dec - 16 Dec
Aldrovandi Residence City Suites
View from property
Trianon Borgo Pio

Aparthotel in Rome City Centre

Trianon Borgo Pio
4.0 star property
9.4 out of 10, Exceptional, (1483)
"Great service and Rooms"
United States
Gloribel
Trianon Borgo Pio
Terrace/patio
master Trevi

Aparthotel in Rome City Centre

master Trevi
4.0 star property
10.0 out of 10, Exceptional, (67)
"Excellent staff, and beautiful rooms"
United States
William
The price is ฿10,067
฿11,630 total
includes taxes & fees
11 Jan - 12 Jan 2026
master Trevi
Exterior
Numa Rome Trastevere

Aparthotel in Gianicolense

Numa Rome Trastevere
9.2 out of 10, Wonderful, (59)
"Clean room, great amenities, good location"
Germany
Efthimios-Enias
The price is ฿2,840
฿3,568 total
includes taxes & fees
14 Jan - 15 Jan 2026
Numa Rome Trastevere
Property entrance
HiSuiteROME

Apartment in Rome City Centre

HiSuiteROME
9.4 out of 10, Exceptional, (395)
"Clean room, amenities, and the staff were Excellent!! "
United States
Diana
The price is ฿9,091
฿10,444 total
includes taxes & fees
6 Jan - 7 Jan 2026
HiSuiteROME
Apartment, 2 Bedrooms, Balcony | Private kitchen | Full-sized fridge, microwave, oven, stovetop
Monti Apartments - My Extra Home

Apartment in Rome City Centre

Monti Apartments - My Extra Home
9.2 out of 10, Wonderful, (423)
"Clean and spacious rooms, safe and great location and value. Customer Service was excellent during the Phone conversations prior to arrival and during the check-in process. "
United States
Edward
Monti Apartments - My Extra Home
Interior
Lungotevere Suite

Residence in Portuense

Lungotevere Suite
8.8 out of 10, Excellent, (325)
"Laundry was excellent ! Everything was great "
Canada
Andreina Maria
The price is ฿2,796
฿3,520 total
includes taxes & fees
6 Jan - 7 Jan 2026
Lungotevere Suite
Large Studio, Kitchenette, Balcon | Premium bedding, memory-foam beds, in-room safe, individually decorated
Numa Rome Vici

Aparthotel in Rome City Centre

Numa Rome Vici
9.2 out of 10, Wonderful, (549)
"Great place to stay in Rome, walking distance to all major places"
United States
Raul
The price is ฿3,623
฿4,430 total
includes taxes & fees
24 Dec - 25 Dec
Numa Rome Vici
Premium bedding, down duvets, memory-foam beds, desk
Roma Resort Colosseum

Apartment in Rome Historic Centre

Roma Resort Colosseum
7.8 out of 10, Good, (386)
"Gorgeous room very convenient and excellent services"
United States
Lizzy
The price is ฿2,760
฿3,480 total
includes taxes & fees
15 Dec - 16 Dec
Roma Resort Colosseum
Seasonal outdoor pool, lifeguards on site
Aparthotel Adagio Rome Vatican

Aparthotel in Trionfale

Aparthotel Adagio Rome Vatican
4.0 star property
8.4 out of 10, Very good, (513)
"Very good property. Would recommend. Has a train station near. "
United States
Victor
The price is ฿2,547
฿3,246 total
includes taxes & fees
19 Dec - 20 Dec
Aparthotel Adagio Rome Vatican
City view from property
Piazzetta Margutta - My Extra Home

Aparthotel in Rome City Centre

Piazzetta Margutta - My Extra Home
9.4 out of 10, Exceptional, (610)
"Spacious room, great walking distance to attractions, quiet and safe. No complaints."
United States
Jian
Piazzetta Margutta - My Extra Home
Food court
Vino e Oli Residenze

Apartment in Vatican

Vino e Oli Residenze
9.6 out of 10, Exceptional, (327)
"The place is spacious and very close to the Vatican city. Room looks just like the photos with a cute lift for moving luggages upstairs. Overall good value for money, would come back again."
Australia
SHI JIE
The price is ฿6,464
฿9,036 total
includes taxes & fees
7 Jan - 8 Jan 2026
Vino e Oli Residenze
Courtyard
Prati Home

Residence in Vatican

Prati Home
9.8 out of 10, Exceptional, (47)
"Very good stay"
United Kingdom
Saif
Prati Home
Apartment, 1 Bedroom, Terrace | Terrace/patio
Colosseo Gardens - My Extra Home

Apartment in Rome City Centre

Colosseo Gardens - My Extra Home
9.4 out of 10, Exceptional, (631)
"Great place to stay for a few days. Location was perfect to walk or use the tube for the sights. Love Rome!"
United Kingdom
Andrew
Colosseo Gardens - My Extra Home
Exterior
Oriana Homèl Roma

Holiday Home in Rome City Centre

Oriana Homèl Roma
8.6 out of 10, Excellent, (122)
"Our family of five really enjoyed our stay in Rome. The apartment was exceptionally modern, very clean, and spacious—perfect for our group. The location was excellent, just a short walk to the Trevi Fountain, Spanish Steps, and Pantheon. We would happily recommend it to others visiting Rome."
Canada
Jennifer
Oriana Homèl Roma
Front of property
Palazzo Cardinal Cesi

Holiday Home in Rome City Centre

Palazzo Cardinal Cesi
9.0 out of 10, Wonderful, (575)
"Courteous staff"
United States
Gregory
Palazzo Cardinal Cesi
Superior Suite, Balcony, Courtyard Area | View from room
Morin 10 Rome Exclusive Suites

Aparthotel in Vatican

Morin 10 Rome Exclusive Suites
8.6 out of 10, Excellent, (51)
"Great spacious rooms!"
United States
Raul
The price is ฿2,851
฿3,580 total
includes taxes & fees
15 Dec - 16 Dec
Morin 10 Rome Exclusive Suites
Apartment, 3 Bedrooms, Balcony | Private kitchen | Fridge, stovetop, espresso maker, cookware/dishes/utensils
JOIVY Cavour 238

Apartment in Rome City Centre

JOIVY Cavour 238
9.6 out of 10, Exceptional, (8)
"✨ My stay at Joivys in Rome was amazing! A cozy place, great vibes, and the perfect location to enjoy the city. I felt comfortable, welcomed, and everything was spotless. Would definitely stay here again! 🇮🇹❤️ "
United States
Andres
The price is ฿3,000
฿5,781 total
includes taxes & fees
15 Dec - 16 Dec
JOIVY Cavour 238
Deluxe Triple Room, 1 King Bed with Sofa bed | In-room safe, desk, soundproofing, free WiFi
Golden Pantheon Rooms

Apartment in Rome City Centre

Golden Pantheon Rooms
9.2 out of 10, Wonderful, (17)
"I really liked these rooms were close abd walkable to tourtist spots"
United States
Diego
The price is ฿3,518
฿4,314 total
includes taxes & fees
6 Jan - 7 Jan 2026
Golden Pantheon Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Lucia Hotel Reviews

hu Roma Camping In Town

hu Roma Camping In Town

10/10 Excellent
"Very good quality and excellent service and excellent customer service "
Muhammad 1-night trip
Posted 1 day ago
hu Roma Camping In Town

Find out more about Santa Lucia

Search for holiday rentals in Santa Lucia on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Lucia using one of the methods below:

  • View our selection of featured holiday rentals in Santa Lucia
  • Use the map to find apartments and other holiday homes in the Santa Lucia neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Lucia while they last

Look no further and take a look at our great range of rental properties in Santa Lucia!

Frequently asked questions

Can I find a holiday rental in Santa Lucia?

Yes, there are holiday rentals close to the most popular sights in Santa Lucia, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Lucia has to offer?

Oriana Homèl Roma: This holiday home rental outside of Santa Lucia is in the city centre, and equipped with air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave.

What’s there to see and do in Santa Lucia?

Explore the area and family-friendly sights such as Bioparco di Roma, or get out into nature at a spot like Villa Borghese. While in the area, you can also visit popular places such as Spanish Steps and Trevi Fountain.

What’s a holiday rental in Santa Lucia like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Lucia. Holiday rentals provide amenities such as WiFi and washers and dryers so you'll feel right at home. If you're concerned about cleanliness, holiday rentals can offer a sense of security away from public hotel lifts and lobbies packed with people while still allowing you the experience of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a family getaway.