Search Hotels in Sant' Ambrogio, Florence

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant' Ambrogio hotels

Mamo Florence - Fiesolana & Fiona Apartments

Mamo Florence - Fiesolana & Fiona Apartments
Sant' Ambrogio
The price is ฿3,842
฿7,918 total
includes taxes & fees
22 Mar - 23 Mar
Mamo Florence - Fiesolana & Fiona Apartments

Hotel Regency

Hotel Regency
5.0 star property
Sant' Ambrogio
9.4 out of 10, Exceptional, (445 reviews)
"Amazing stay as always. Beautiful hotel but the staff make it great. Feels like a home away from home. Perfect location that is easily walkable everywhere in the historic center."
United States
Aaron
The price is ฿14,947
฿17,051 total
includes taxes & fees
28 Mar - 29 Mar
Hotel Regency

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Sant' Ambrogio
10.0 out of 10, Exceptional, (15 reviews)
"This hotel was quite the find! The staff was amazing, attentive, respectful. The amenities, attention to detail, experience was amazing! We will definitely be back."
United States
Nicole
The price is ฿14,558
฿16,623 total
includes taxes & fees
23 Mar - 24 Mar
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

B&B di Piazza del Duomo

B&B di Piazza del Duomo
Sant' Ambrogio
9.2 out of 10, Wonderful, (262 reviews)
"Lovely location and the room is a good size with everything you need."
United Kingdom
Evie
The price is ฿4,948
฿5,900 total
includes taxes & fees
22 Mar - 23 Mar
B&B di Piazza del Duomo

Palazzo Pazzi Vitali Luxury Apartments

Palazzo Pazzi Vitali Luxury Apartments
Sant' Ambrogio
10.0 out of 10, Exceptional, (1 review)
"This property is under-rated and we are thankful we stumbled upon this. We had a nearly 3000 sf apartment to ourselves and the photos don't do it justice. We stay at luxury lodging everywhere we go and this was no different. There was so much room to relax and spread out. Great for multi family, or large family. Our unit on the second floor was ideal because the bedrooms were in the ack and very quiet. While the main living areas overlook this beautiful street with opera singers and live...
United States
Richard
The price is ฿27,480
฿38,297 total
includes taxes & fees
27 Mar - 28 Mar
Palazzo Pazzi Vitali Luxury Apartments

Breathtaking 4BD Apt 5min Walk to Duomo

Breathtaking 4BD Apt 5min Walk to Duomo
Sant' Ambrogio
8.0 out of 10, Very good, (6 reviews)
"The apartment was in excellent arrangement—clean, comfortable, and beautifully decorated. We especially loved how close it was to the Duomo; the location couldn’t have been better. Everything was perfect and made our time in Florence truly special."
United States
Lizette
Breathtaking 4BD Apt 5min Walk to Duomo

Genteel Home Giraldi

Genteel Home Giraldi
Sant' Ambrogio
The price is ฿23,210
฿32,270 total
includes taxes & fees
3 Apr - 4 Apr
Genteel Home Giraldi

Hotel Bavaria

Hotel Bavaria
1.0 star property
Sant' Ambrogio
8.2 out of 10, Very good, (424 reviews)
"Simple but cost effective hotel. Amazing location."
United Kingdom
Bernardo Correa
The price is ฿2,630
฿3,159 total
includes taxes & fees
23 Mar - 24 Mar
Hotel Bavaria

Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca
Sant' Ambrogio
9.8 out of 10, Exceptional, (57 reviews)
"Most memorable magical stay staff was extremely helpful. Place was beautiful beyond our expectations area was perfect to walk to everything. Highly recommend this location. "
United States
Miriam
The price is ฿4,003
฿4,860 total
includes taxes & fees
25 Mar - 26 Mar
Dimora del Cardinale - Residenza d'epoca

Alfani Modern Loft by MMega

Alfani Modern Loft by MMega
Sant' Ambrogio
The price is ฿4,353
฿9,052 total
includes taxes & fees
22 Mar - 23 Mar
Alfani Modern Loft by MMega

Mamo Florence - Dante & Virgilio Apartments

Mamo Florence - Dante & Virgilio Apartments
Sant' Ambrogio
9.8 out of 10, Exceptional, (9 reviews)
"Clean, good location. Hard pillows and smelled a bit musty.eberything worked well."
United States
James
The price is ฿3,082
฿7,653 total
includes taxes & fees
24 Mar - 25 Mar
Mamo Florence - Dante & Virgilio Apartments

Appartamento Puccini

Appartamento Puccini
Sant' Ambrogio
7.8 out of 10, Good, (76 reviews)
"The apartment is located perfectly"
Germany
Thomas
The price is ฿2,989
฿4,506 total
includes taxes & fees
21 Apr - 22 Apr
Appartamento Puccini

Hotel Cardinal Of Florence

Hotel Cardinal Of Florence
3.0 star property
Sant' Ambrogio
8.6 out of 10, Excellent, (324 reviews)
"The service staff was very helpful and courteous, the hotel is near a lot of really nice sites. "
United States
Santiago
The price is ฿4,588
฿5,504 total
includes taxes & fees
22 Mar - 23 Mar
Hotel Cardinal Of Florence

Residenza D'Epoca Sant'Egidio

Residenza D'Epoca Sant'Egidio
Sant' Ambrogio
7.4 out of 10, Good, (111 reviews)
"We loved this place! So much room! Old vibe just what we wanted! Easy check in. Very clean. "
United States
Michael
The price is ฿2,208
฿2,886 total
includes taxes & fees
29 Mar - 30 Mar
Residenza D'Epoca Sant'Egidio

Residenza d'Epoca Borgo Albizi

Residenza d'Epoca Borgo Albizi
Sant' Ambrogio
7.8 out of 10, Good, (259 reviews)
"Everything worked nicely and as expected, kind staff and a clean room!"
United States
Eira Magdalena
The price is ฿3,333
฿4,123 total
includes taxes & fees
22 Mar - 23 Mar
Residenza d'Epoca Borgo Albizi

Don Giovanni by Mmega

Don Giovanni by Mmega
Sant' Ambrogio
9.0 out of 10, Wonderful, (8 reviews)
"Perfect location Very clean Nicely appointed"
United States
Luanne
The price is ฿4,837
฿8,822 total
includes taxes & fees
7 Apr - 8 Apr
Don Giovanni by Mmega

Mamo Florence - Mattonaia Apartment

Mamo Florence - Mattonaia Apartment
Sant' Ambrogio
10.0 out of 10, Exceptional, (1 review)
The price is ฿14,808
฿20,932 total
includes taxes & fees
4 Apr - 5 Apr
Mamo Florence - Mattonaia Apartment

Wine Apartments Florence Sagrantino

Wine Apartments Florence Sagrantino
Sant' Ambrogio
The price is ฿2,460
฿9,862 total
includes taxes & fees
22 Mar - 23 Mar
Wine Apartments Florence Sagrantino

Residenza Maglioni in San Pierino

Residenza Maglioni in San Pierino
Sant' Ambrogio
Residenza Maglioni in San Pierino

Oriuolo - Flo Apartments

Oriuolo - Flo Apartments
Sant' Ambrogio
Oriuolo - Flo Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Sant' Ambrogio Hotel Reviews

Frequently asked questions

What's it like in Sant' Ambrogio?
Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighbourhood has to offer. Make sure that you visit Via Vincenzo Gioberti and Piazza Massimo D'Azeglio as part of your Sant' Ambrogio travel plans.
What's a favourite hotel to stay in Sant' Ambrogio?
Based on Expedia customer reviews, Dimora del Cardinale - Residenza d'epoca is the highest ranked property in Sant' Ambrogio. This B&B is a short 7-minute walk from Cathedral of Santa Maria del Fiore, and it offers free WiFi and pillowtop beds. Other favourite options in the area include Alfieri9 and B&B di Piazza del Duomo.
How many hotels can I expect to find in Sant' Ambrogio?
If you're searching for places to stay in Florence, Expedia has something to meet your needs with 521 Sant' Ambrogio hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available in Sant' Ambrogio.
What is there to do around this Florence neighbourhood?
Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Via Vincenzo Gioberti and Piazza Massimo D'Azeglio are also a couple of places to visit in the neighbourhood. Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are some popular places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, Jewish Museum and FiesoleBike Day Tours are also worth a stop.