Search Hotels in Serra Mesa, San Diego

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6 Nov - 7 Nov
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7 Nov - 8 Nov
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7 Nov - 9 Nov
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14 Nov - 16 Nov

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Top Trending Hotels Near Serra Mesa, San Diego

Terrace/patio
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4.0 star property
8.4 out of 10, Very good, (6004)
"Clean room, friendly staff. Enjoyed my stay. "
United States
Marcus Robert
The price is ฿4,392
฿6,034 total
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4.0 star property
9.0 out of 10, Wonderful, (3042)
"The room was clean and comfortable, the food was great and convenient proximity to the convention center. "
United States
Kethel
The price is ฿5,527
฿7,902 total
includes taxes & fees
23 Nov - 24 Nov
Hard Rock Hotel San Diego
Rooftop terrace
Palihotel San Diego Gaslamp Quarter
Palihotel San Diego Gaslamp Quarter
4.0 star property
8.6 out of 10, Excellent, (1992)
"staff was very friendly and hotel was clean"
United States
Stephany
The price is ฿4,202
฿4,872 total
includes taxes & fees
9 Nov - 10 Nov
Palihotel San Diego Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
9.0 out of 10, Wonderful, (1197)
"Clean room ,friendly staff, great location "
United States
Jessica
The price is ฿4,115
฿4,772 total
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel
3.5 star property
9.2 out of 10, Wonderful, (3366)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is ฿4,065
฿4,480 total
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Marina Gateway Hotel
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
9.0 out of 10, Wonderful, (2640)
"Very nice location and rooms. "
United States
David
The price is ฿5,404
฿7,147 total
includes taxes & fees
28 Nov - 29 Nov
The Horton Grand, Downtown/Gaslamp Quarter
Lobby
Gaslamp Plaza Suites
Gaslamp Plaza Suites
3.5 star property
8.8 out of 10, Excellent, (1001)
"Nice and comfortable room"
United States
Jim
The price is ฿3,672
฿4,177 total
includes taxes & fees
12 Nov - 13 Nov
Gaslamp Plaza Suites
Property entrance
The Bristol Hotel San Diego
The Bristol Hotel San Diego
3.5 star property
8.6 out of 10, Excellent, (1406)
"Nice staff, comfortable beds"
United States
Amber
The price is ฿5,170
฿5,994 total
includes taxes & fees
29 Nov - 30 Nov
The Bristol Hotel San Diego
Garden
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4.0 star property
9.2 out of 10, Wonderful, (2919)
"Great hotel"
United States
Michael
The price is ฿5,571
฿6,403 total
includes taxes & fees
10 Nov - 11 Nov
Legacy Resort Hotel & Spa
Front of property
The Sofia Hotel
The Sofia Hotel
3.5 star property
8.4 out of 10, Very good, (1614)
"I loved the stay here, highly recommended "
United States
Tanya
The price is ฿18,438
฿22,154 total
includes taxes & fees
3 Dec - 4 Dec
The Sofia Hotel
Exterior
La Pensione Hotel
La Pensione Hotel
3.0 star property
8.6 out of 10, Excellent, (1932)
"Friendly, helpful staff and clean well appointed rooms. "
United States
Sandi
La Pensione Hotel
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
9.4 out of 10, Exceptional, (1003)
"Great hotel and location. "
United States
Craig
The price is ฿3,288
฿4,752 total
includes taxes & fees
23 Nov - 24 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay
The Dana on Mission Bay
3.5 star property
8.8 out of 10, Excellent, (3833)
"Such a beautiful resort style hotel with great staff!"
United States
Madelyn
The price is ฿5,167
฿6,588 total
includes taxes & fees
23 Nov - 24 Nov
The Dana on Mission Bay
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
3.0 star property
8.0 out of 10, Very good, (1385)
"Rooms were clean and staff was great. "
United States
Luis
The price is ฿3,297
฿3,790 total
includes taxes & fees
11 Nov - 12 Nov
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
8.0 out of 10, Very good, (2383)
"We loved our stay, great price, very clean and excellent location! "
United States
Brenda
The price is ฿2,872
฿3,302 total
includes taxes & fees
12 Nov - 13 Nov
Days Inn by Wyndham San Diego Hotel Circle
Check-in/check-out kiosk
Urban Boutique Hotel
Urban Boutique Hotel
3.0 star property
8.6 out of 10, Excellent, (1293)
"Very nice staff and good food nearby. They had issues with the card printer but was very quick and nice about helping me get into my room everytime I needed to."
United States
Fred
Urban Boutique Hotel
Standard Room, 1 King Bed, Non Smoking, City View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
3.0 star property
8.8 out of 10, Excellent, (612)
"It was a good stay for a night, check-in and check-out went well! I would stay here again. "
United States
Ehsan
The price is ฿3,362
฿3,898 total
includes taxes & fees
23 Nov - 24 Nov
The DEXTRO Little Italy, BW Premier Collection
Outdoor pool
Courtyard by Marriott San Diego Downtown Little Italy
Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
8.2 out of 10, Very good, (1181)
"Great location and hotel! Loved my stay "
United States
Banesa
The price is ฿3,964
฿4,596 total
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott San Diego Downtown Little Italy
Exterior
Bay Club Hotel & Marina
Bay Club Hotel & Marina
3.5 star property
9.0 out of 10, Wonderful, (3067)
"Clean & relaxing place with lovely staff!"
United States
Shida
The price is ฿3,831
฿4,404 total
includes taxes & fees
30 Nov - 1 Dec
Bay Club Hotel & Marina
Front of property
Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista
2.0 star property
7.2 out of 10, Good, (1967)
"Good hotel "
United States
Nubia
The price is ฿2,087
฿2,296 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Palmeras Chula Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels in Serra Mesa with a pool

Lobby
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
3.0 star property
  • Pool
7.4 out of 10, Good, (4046)
The price is ฿2,747
฿3,158 total
includes taxes & fees
13 Nov - 14 Nov
Wyndham Garden San Diego Near SeaWorld
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Top guest rated hotels in Serra Mesa

Hot springs
The Atwood Hotel San Diego - SeaWorld/Zoo
The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
    8.0 out of 10, Very good, (1775)
    The price is ฿3,195
    ฿3,672 total
    includes taxes & fees
    12 Nov - 13 Nov
    The Atwood Hotel San Diego - SeaWorld/Zoo
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    Where to stay in Serra Mesa

    Find the best Serra Mesa areas for the activities you enjoy most.

    Downtown San Diego

    Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

    Gaslamp Quarter featuring a bar, night scenes and street scenes

    Gaslamp Quarter

    San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

    Pacific Beach Park showing a beach

    Pacific Beach

    Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

    Belmont Park featuring a park and rides

    Mission Beach

    If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

    Ocean Beach

    Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

    Top Serra Mesa Hotel Reviews

    Hampton Inn & Suites by Hilton San Diego SeaWorld

    Hampton Inn & Suites by Hilton San Diego SeaWorld

    10/10 Excellent
    "It was wonderful stay"
    Alejandra 2-night trip
    Posted 2 days ago
    Hampton Inn & Suites by Hilton San Diego SeaWorld

    Explore a world of travel with Expedia

    Frequently asked questions

    What's it like in Serra Mesa?
    Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
    How many hotels can I expect to find in the Serra Mesa area?
    Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
    If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
    Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
    What can I see and do in this San Diego neighbourhood?
    Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.