Regis is a neighbourhood that travellers like for its jazz scene, golf courses and university setting. Are you looking for Regis travel tips? Make sure that you visit Clear Creek and Willis Case Golf Course while you're in the neighbourhood.

Where is the best hotel for a stay in Regis?

For your stay in Regis, Motel 6 Denver, CO – Downtown is one of the top choices based on our traveller data.

How many hotels will I be able to find in Regis?

Book one of Expedia's 7 hotels and other accommodation options in Regis and start exploring everything Denver has to offer.

If I need to cancel my hotel reservation in Regis, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best options available in Regis.

What can I see and do in this Denver neighbourhood?

A few attractions you might want to check out while you're in Regis are Clear Creek and Willis Case Golf Course. While you're out sightseeing in Denver, make sure that you visit other sights such as William Scheitler Recreation Center or The Oriental Theater.

The Best Hotels in Regis, Denver - 2026 Updated Prices

A large, historic building with a prominent clock tower and a statue in front.

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Our top choices for Regis hotels

A modern hotel with a prominent '6' sign, multiple floors, and a parking lot with several cars.

1. Motel 6 Denver, CO – Downtown

Regis

Perla

฿2,283 total

includes taxes & fees

5 Nov - 6 Nov

2. Holiday Inn Express Denver Central North by IHG

5.5 km from Regis

Isaiah

฿3,073 total

includes taxes & fees

26 Nov - 27 Nov

A modern outdoor seating area with white sofas, planters, and umbrellas.

3. Hilton Garden Inn Denver Union Station, CO

LoDo, 5.1 km from Regis

Nicole

฿4,777 total

includes taxes & fees

26 Nov - 27 Nov

A modern hotel with a glass facade, multiple floors, and a prominent signage for SpringHill Suites.

4. SpringHill Suites by Marriott Denver Downtown

Auraria, 5.6 km from Regis

Haley

฿5,092 total

includes taxes & fees

23 Nov - 24 Nov

A Hilton hotel entrance with a glass facade, illuminated signage, and a modern architectural design.

5. Hilton Denver City Center

Downtown Denver, 6.5 km from Regis

Brandi

฿5,089 total

includes taxes & fees

29 Nov - 30 Nov

A multi-story hotel with a prominent 'Hyatt Place' sign at the top.

6. Hyatt Place Denver Downtown

Downtown Denver, 6.7 km from Regis

Randy

฿4,193 total

includes taxes & fees

27 Nov - 28 Nov

A rooftop terrace with outdoor seating, potted plants, and a view of the cityscape.

7. Vīb Hotel by Best Western Denver RiNo

River North Art District, 6 km from Regis

Karah

฿4,381 total

includes taxes & fees

24 Nov - 25 Nov

A hotel entrance with a sign reading 'HOTEL TEATRO' and a street sign indicating '14th Street Denver.'

8. Hotel Teatro

Downtown Denver, 6 km from Regis

YUSUKE

฿5,958 total

includes taxes & fees

24 Nov - 25 Nov

A rooftop pool area with lounge chairs and a view of the cityscape.

9. The Rally Hotel at McGregor Square

LoDo, 5.5 km from Regis

Charles

฿9,094 total

includes taxes & fees

23 Nov - 24 Nov

A modern hotel with a prominent sign, multiple floors, and a parking sign visible.

10. Home2 Suites by Hilton Denver Downtown Convention Center

Downtown Denver, 6.4 km from Regis

Adriana

฿4,129 total

includes taxes & fees

29 Nov - 30 Nov

A modern kitchen with stainless steel appliances, wooden flooring, and a brick wall.

11. Catbird Hotel

6.4 km from Regis

Rolando

฿5,511 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with a large arched window, a leather sofa, two potted plants, and a bicycle mounted on the wall.

12. Origin Westminster a Wyndham Hotel

8 km from Regis

Denise

฿4,839 total

includes taxes & fees

10 Nov - 11 Nov

A modern hotel room with a living area, kitchenette, and a large window offering a view.

13. Hyatt House Denver Airport

23.8 km from Regis

Whitney

฿4,459 total

includes taxes & fees

31 Oct - 1 Nov

A modern lounge area with a geometric patterned wall, a central round table, and four grey upholstered chairs.

14. Tru By Hilton Denver Downtown Convention Center

Downtown Denver, 6.3 km from Regis

Camdon

฿3,948 total

includes taxes & fees

25 Nov - 26 Nov

A red convertible parked in front of a building with large windows and a decorative entrance.

15. The Oxford Hotel

LoDo, 5.5 km from Regis

Delaney

฿8,732 total

includes taxes & fees

23 Nov - 24 Nov

An outdoor seating area with sofas, a fire pit, and string lights.

16. Hyatt Place Denver/Westminster

10.9 km from Regis

Evita

฿4,881 total

includes taxes & fees

5 Nov - 6 Nov

A modern living area with a bar, seating arrangements, and a fireplace.

17. Le Meridien Denver Downtown

Downtown Denver, 6.5 km from Regis

David

฿6,602 total

includes taxes & fees

28 Nov - 29 Nov

A modern dining area with long communal tables, chairs, and a long counter.

18. Element by Marriott Denver Downtown East

7 km from Regis

Steve

฿4,302 total

includes taxes & fees

27 Nov - 28 Nov

19. Hyatt House Denver Downtown

Downtown Denver, 6.7 km from Regis

Anthony

฿4,489 total

includes taxes & fees

24 Nov - 25 Nov

A multi-story hotel with a prominent City Express sign, a covered entrance, and a brick facade.

20. City Express by Marriott Denver Airport

23.3 km from Regis

Justine

฿4,029 total

includes taxes & fees

27 Nov - 28 Nov

View all properties

Compare popular hotels in Regis

Property	Property class	Guest rating
Motel 6 Denver, CO – Downtown	2.0 star property	7.4 Good 1,528 reviews	View
Holiday Inn Express Denver Central North by IHG	2.5 star property	8.8 Excellent 475 reviews	View
SpringHill Suites by Marriott Denver Downtown	3.5 star property	9.4 Exceptional 1,386 reviews	View
Hilton Garden Inn Denver Union Station, CO	3.5 star property	9.2 Wonderful 2,491 reviews	View
The Oxford Hotel	4.5 star property	9.6 Exceptional 1,083 reviews	View

Where to stay in Regis

Find the best Regis areas for the activities you enjoy most.

A modern architectural complex with geometric shapes and a prominent red sculpture.

Downtown Denver

Discover Denver is at its most dynamic in this central district, which has cool craft breweries, bars, galleries, boutiques and entertainment venues.

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A city street with a large canopy structure, modern buildings, and potted plants.

Cherry Creek

Abundant dining options and stunning river views are well-reviewed features of Cherry Creek. Make a stop by top sights like Cherry Creek Shopping Center while you're exploring the area.

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A cityscape with modern buildings and a forested area in the foreground.

Denver Tech Center

Known for its ample dining options and great live music, there's plenty to explore in Denver Tech Center. You can visit top attractions like Fiddler's Green Amphitheatre and The Landmark Theatre Greenwood Village, and jump on the metro at Orchard Station or Arapahoe at Village Center Station to see more of the city.

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A city skyline with a prominent stadium and surrounding high-rise buildings.

LoDo

Visitors often come to LoDo for its abundant dining options, but many stay to explore sights like Union Station and McGregor Square. Getting around the area on the metro is easy if you take a ride at Union Station-Coors Field-16th St. Mall Station.

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A rural landscape with a field of corn, a bridge, and houses in the background.

Highlands Ranch

Highlands Ranch is known for its abundant dining options, and you can plan a trip to South Suburban Sports Complex and Chatfield State Park while you're in town.

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Top Regis Hotel Reviews

Spark by Hilton Denver East I 70

10/10 Excellent

"It was clean well kept staff was very nice 👍👍"

Hyatt Centric Downtown Denver

10/10 Excellent

"Spacious room right downtown. Downtown bus/tram very close. Convenient to Union Station. Very walkable location. The only negative was that the bed was not well made. The bottom sheet was not pulled up all the way, so the mattress was exposed. We did not realize this until very late and tried to fix it ourselves. Otherwise, we liked the hotel and would stay here again (we would check the bed out sooner next time)."

Search Hotels in Regis, Denver

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Our top choices for Regis hotels

1. Motel 6 Denver, CO – Downtown

2. Holiday Inn Express Denver Central North by IHG

3. Hilton Garden Inn Denver Union Station, CO

4. SpringHill Suites by Marriott Denver Downtown

5. Hilton Denver City Center

6. Hyatt Place Denver Downtown

7. Vīb Hotel by Best Western Denver RiNo

8. Hotel Teatro

9. The Rally Hotel at McGregor Square

10. Home2 Suites by Hilton Denver Downtown Convention Center

11. Catbird Hotel

12. Origin Westminster a Wyndham Hotel

13. Hyatt House Denver Airport

14. Tru By Hilton Denver Downtown Convention Center

15. The Oxford Hotel

16. Hyatt Place Denver/Westminster

17. Le Meridien Denver Downtown

18. Element by Marriott Denver Downtown East

19. Hyatt House Denver Downtown

20. City Express by Marriott Denver Airport

Compare popular hotels in Regis

Where to stay in Regis

Downtown Denver

Cherry Creek

Denver Tech Center

LoDo

Highlands Ranch

Top Regis Hotel Reviews

Spark by Hilton Denver East I 70

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