Search Hotels Near Mercy Hospital South, St. Louis

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Our top choices for Mercy Hospital South hotels

Lobby
Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South
2.5 star property
3.2 km from Mercy Hospital South
9.6 out of 10, Exceptional, (326)
"nice spot right off the interstate."
United States
Jeffrey
The price is ฿3,646
฿4,193 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis South
Property amenity
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
3.4 km from Mercy Hospital South
9.6 out of 10, Exceptional, (1001)
"Room was very clean! enjoyed the amenities!"
United States
tiffany
The price is ฿3,235
฿3,720 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Lobby
Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
2.5 star property
3.4 km from Mercy Hospital South
9.6 out of 10, Exceptional, (1000)
"Really nice rooms and staff , good breakfast!"
United States
Jerry
The price is ฿3,717
฿4,274 total
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn & Suites St. Louis/South I-55
Bar (on property)
Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
6 km from Mercy Hospital South
9.2 out of 10, Wonderful, (398)
"Great staff, excellent remodel! Beautiful property. "
United States
WILLIAM
The price is ฿3,423
฿4,076 total
includes taxes & fees
9 Jan - 10 Jan 2026
Holiday Inn St Louis SW - Route 66 by IHG
Lobby
Comfort Suites St. Louis - Sunset Hills

Comfort Suites St. Louis - Sunset Hills

Comfort Suites St. Louis - Sunset Hills
2.5 star property
5.5 km from Mercy Hospital South
9.0 out of 10, Wonderful, (195)
"The hotel was very clean and the beds were great."
United States
Toni
The price is ฿3,575
฿4,155 total
includes taxes & fees
19 Jan - 20 Jan 2026
Comfort Suites St. Louis - Sunset Hills
Lobby
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
7 km from Mercy Hospital South
9.4 out of 10, Exceptional, (1003)
"Always very pleasant staff!"
United States
Julie
The price is ฿2,826
฿3,267 total
includes taxes & fees
27 Dec - 28 Dec
Pear Tree Inn St. Louis Arnold
Free breakfast
Best Western Plus Fenton

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
6.9 km from Mercy Hospital South
9.2 out of 10, Wonderful, (179)
"Clean room, nice staff, great food, and great service "
United States
Thuy
The price is ฿3,184
฿3,677 total
includes taxes & fees
23 Dec - 24 Dec
Best Western Plus Fenton
Lobby
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
7 km from Mercy Hospital South
9.6 out of 10, Exceptional, (1000)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is ฿3,863
฿4,465 total
includes taxes & fees
25 Dec - 26 Dec
Drury Inn & Suites St. Louis Arnold
Lobby
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
6.6 km from Mercy Hospital South
8.4 out of 10, Very good, (1372)
"Excellent staff , location was great but the breakfast wasn’t very good"
United States
Christian
The price is ฿2,954
฿3,455 total
includes taxes & fees
23 Dec - 24 Dec
Best Western St. Louis-Kirkwood Route 66
Miscellaneous
The Lodge at Grant's Trail

The Lodge at Grant's Trail

The Lodge at Grant's Trail
3.5 star property
7.9 km from Mercy Hospital South
9.6 out of 10, Exceptional, (469)
"I stayed in the Christmas room after our work Christmas party in the Grand Room! It was cozy and perfect! Breakfast in the morning was freshly prepared, eggs cooked to order, and delicious! "
United States
Kimberly
The price is ฿4,680
฿5,381 total
includes taxes & fees
22 Dec - 23 Dec
The Lodge at Grant's Trail
Reception
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
8.5 km from Mercy Hospital South
8.0 out of 10, Very good, (1047)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is ฿2,670
฿3,084 total
includes taxes & fees
22 Dec - 23 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
6 km from Mercy Hospital South
8.0 out of 10, Very good, (1002)
"Nice Staff, Clean Rooms, Good Area!!"
United States
Keyaira
The price is ฿3,017
฿3,507 total
includes taxes & fees
5 Jan - 6 Jan 2026
La Quinta Inn & Suites by Wyndham St Louis Route 66
Lobby
Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
3.0 star property
8.7 km from Mercy Hospital South
8.8 out of 10, Excellent, (1001)
"Everything was fine for a budget hotel."
United States
John A
The price is ฿3,455
฿3,990 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
8.6 km from Mercy Hospital South
7.8 out of 10, Good, (1119)
"Staff friendly Clean"
United States
SHERRY
The price is ฿2,483
฿2,867 total
includes taxes & fees
24 Dec - 25 Dec
Wingate by Wyndham St. Louis/Fenton Route 66
5 restaurants, breakfast, lunch, dinner served; American cuisine
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
10.4 km from Mercy Hospital South
9.0 out of 10, Wonderful, (1449)
"Awesome place to stay!!"
United States
Kaitlyn
The price is ฿3,109
฿4,076 total
includes taxes & fees
23 Dec - 24 Dec
River City Casino & Hotel
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
14.2 km from Mercy Hospital South
9.4 out of 10, Exceptional, (838)
"Clean, would stay again."
United States
Eryka
The price is ฿3,177
฿3,897 total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott St. Louis Brentwood
Exterior
MainStay Suites St. Louis - Galleria

MainStay Suites St. Louis - Galleria

MainStay Suites St. Louis - Galleria
2.5 star property
14.4 km from Mercy Hospital South
6.6 out of 10, (63)
"Staff were very friendly and our room was great!"
United States
William
The price is ฿2,910
฿3,397 total
includes taxes & fees
28 Dec - 29 Dec
MainStay Suites St. Louis - Galleria
Lobby
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
10.7 km from Mercy Hospital South
9.4 out of 10, Exceptional, (1004)
"Clean room, breakfast, and friendly staff"
United States
Angie
The price is ฿3,612
฿4,225 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites Southwest St. Louis
Lobby
Best Western St. Louis Inn

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
4.9 km from Mercy Hospital South
8.0 out of 10, Very good, (1002)
"Good staff, smooth and welcome checkin"
United States
Amit
The price is ฿2,269
฿2,609 total
includes taxes & fees
29 Dec - 30 Dec
Best Western St. Louis Inn
Exterior
Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County
3.0 star property
12.9 km from Mercy Hospital South
9.0 out of 10, Wonderful, (452)
"Very nice place to stay. "
United States
John
The price is ฿4,119
฿4,736 total
includes taxes & fees
1 Jan - 2 Jan 2026
Courtyard by Marriott St. Louis West County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mercy Hospital South Hotel Reviews

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent
"The room did smell weird when I first opened the door. The water was cold in the shower so had to hurry and shower before it get cold again "
Dominique 1-night trip
Posted 6 days ago
Wingate by Wyndham St. Louis/Fenton Route 66

Hotels near other Mercy Hospital South attractions

Suson Park in St. Louis. They have several pavilions for BBQs and events. They have a barn area with animals too. We enjoyed time with family and friends today under a pavilion.
Photo by TtotheP ✈️ 🚗 ❤️‍ 📷
Open Photo by TtotheP ✈️ 🚗 ❤️‍ 📷

Suson Park

Explore the great outdoors at Suson Park, a lovely green space in Tesson Ferry. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Cows alongside Clydesdale horses and other animals
Photo by lukky4mine@yahoo.com Lucky
Open Photo by lukky4mine@yahoo.com Lucky

Grant's Farm

4.5/5 (272 reviews)
This historic homestead just outside St. Louis has more than 900 animals and a Bavarian farmhouse that serves up a hearty, traditional lunch.
See properties

Frequently asked questions

What's the area like around Mercy Hospital South?
Mercy Hospital South is located in Sappington. You'll find 39 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Mercy Hospital South?
Holiday Inn Express & Suites St. Louis South - I-55 by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 2.1 mi (3.4 km) from Mercy Hospital South. Other good options within 5 miles include Hampton Inn & Suites St. Louis/South I-55 and Fairfield Inn & Suites by Marriott St. Louis South.
How many hotels will I find near Mercy Hospital South?
Expedia has 39 hotels and other accommodation options a few miles from Mercy Hospital South.
If I need to cancel the hotel reservation for my stay near Mercy Hospital South, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mercy Hospital South.
What can I see and do near Mercy Hospital South?
Sights like Ulysses S. Grant National Historic Site and Hawken House highlight some of the local culture. Consider spending a leisurely afternoon outside at Laumeier Sculpture Park, Sylvan Springs County Park or St Johns Community Dog Park. Kennedy Rink, BounceU of St. Louis and Grant's Farm are some favourites close by Mercy Hospital South.