Ancient Roman ruins with columns, a temple, and a cityscape at sunset.

Search Holiday Rentals in Mediterranean Region

Where to?

Dates

November 2026

December 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Mediterranean Region holiday rentals

A modern kitchen with a central island, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

1. Varaba Country House

Markopoulo Mesogaias

Emily

฿2,362 total

includes taxes & fees

16 Nov - 17 Nov

A glass table with a decorative glass bowl, a bed with a yellow headboard, and wooden blinds in a room with a view.

2. Carpe Diem Apartments By Athens Airport

Markopoulo

Marissa

฿2,103 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor café with tables and chairs, surrounded by purple flowering trees.

3. Appart'Hotel-Restaurant Castel Emeraude

Arles-sur-Tech

Filippo

฿1,817 total

includes taxes & fees

4 Dec - 5 Dec

A multi-story hotel with a pool area, featuring a large pool, sun loungers, and a well-lit exterior.

4. Masd Mediterráneo Hotel & Apartamentos

Castelldefels

Messina

฿3,766 total

includes taxes & fees

7 Dec - 8 Dec

A hotel room with a large bed, a bedside table, a lamp, and a view of a dome through a window.

5. San Giuliano Inn - Adults Only

Historic Centre of Florence

Neil

฿4,127 total

includes taxes & fees

3 Dec - 4 Dec

A hotel reception area with a check-in counter, seating area, and large windows offering views of the street.

6. Appart'hôtel Odalys City - Monaco Les Hauts de la Principauté

Beausoleil

Agostina

฿2,914 total

includes taxes & fees

24 Nov - 25 Nov

A balcony with a table, wine glasses, and a bottle, overlooking a historic building with a clock tower and another tower.

7. Relais Piazza Signoria

Historic Centre of Florence

David

฿4,249 total

includes taxes & fees

3 Dec - 4 Dec

A rooftop pool with a clear view of historic buildings and mountains in the background.

8. Teatro Luxury Apartments Firenze - Starhotels Collezione

Historic Centre of Florence

Jahzier

฿6,821 total

includes taxes & fees

22 Nov - 23 Nov

A modern lobby with leather sofas, a glass coffee table, and potted plants.

9. Residhome Marseille

Old Port of Marseille

Robert

฿3,111 total

includes taxes & fees

4 Dec - 5 Dec

A rooftop pool area with lounge chairs and a sofa, overlooking a beach and the sea.

10. Gran Hotel Guadalpin Banus

Puerto Banús

Paul

฿4,371 total

includes taxes & fees

25 Nov - 26 Nov

A coastal cityscape with multi-story buildings, a sandy beach, and rocky foreground.

11. Ona Princesa Playa

Marbella City Centre

German

฿2,429 total

includes taxes & fees

8 Dec - 9 Dec

A poolside area with a swimming pool, outdoor seating, and a staircase leading to an upper level.

12. Rimondi Boutique Hotels-Small Luxury Hotels of the World

Old Town Rethymnon

柜彣

฿7,335 total

includes taxes & fees

12 Nov - 13 Nov

An outdoor dining area with multiple tables and chairs, surrounded by plants and hanging lights.

13. Hu Firenze Camping In Town

Florence

Debra

฿2,164 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio with wicker furniture, green tables, and red umbrellas.

14. Hôtel Soléo Prado

8th Arrondissement

Sofia

฿3,203 total

includes taxes & fees

29 Nov - 30 Nov

A modern bedroom with a large bed, a desk with chairs, and a bathroom visible through an open door.

15. Palazzo Mannaioni Suites

Historic Centre of Florence

Heather

฿3,864 total

includes taxes & fees

30 Nov - 1 Dec

A balcony with a view of the beach and ocean.

16. Vila Gale Ampalius Resort Hotel

Vilamoura

Varun

฿5,022 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, a chair, a nightstand, and a window with curtains.

17. La Casa Del Sol Hotel

Gràcia

Erin Ebru

฿4,568 total

includes taxes & fees

23 Nov - 24 Nov

A bathtub with a view of a body of water and a distant landmass.

18. Nano Oia Villas

Santorini

Danner

฿4,418 total

includes taxes & fees

13 Nov - 14 Nov

A rooftop terrace with a seating area, a potted plant, and a stack of stones.

19. Residhome Nice Promenade

Nice City Centre

Truong

฿2,397 total

includes taxes & fees

13 Nov - 14 Nov

20. NH Marina Portimao Resort

Praia da Rocha

Courtney

฿2,968 total

includes taxes & fees

15 Nov - 16 Nov

View all properties

Find holiday rentals that suit your style

Top Mediterranean Region Hotel Reviews

A spacious lobby with a central seating area, large windows, and a high ceiling.

Only YOU Hotel Sevilla

San Pablo-Santa Justa

10/10 Excellent

Alex

A modern house with a glass facade, a green garden, and a small patio area.

Hotel De Provence

Cannes City Centre

10/10 Excellent

Rhodri

A modern dining area with a white table and chairs, decorative light fixtures, and shelves with various items including vases and baskets.

Palais Saleya Boutique Hôtel

Nice City Centre

10/10 Excellent

Fantastic experience staying at the Palais Saleya Apartment & Suite, with friendly and helpful staff. Stayed here for 10 days, family of 3. Location is superb with access to many amenities - easy access to food, shopping and beach. Easy access from the airport either via public bus or via taxi. Have stayed in other hotels along the Nice Promenade and have thoroughly enjoyed a change to staying in a well equipped apartment instead. Highly recommended for the more adventurous !

Coenraad

A modern bathroom with a marble floor and walls, a large white sink, and a mirror with two round mirrors above it.

Boutique Hôtel Nice Côte d'Azur

Nice City Centre

10/10 Excellent

Richard Andrew Jairzinho

A courtyard with a pathway leading to a building entrance, surrounded by greenery and outdoor seating.

Grand Juste

5th Arrondissement

10/10 Excellent

Julia

A building with ornate architectural details, including columns and balconies, and a palm tree in the foreground.

Gounod Hotel

Nice City Centre

10/10 Excellent

christina

A spacious lobby with a modern chandelier, seating area, and a patterned floor.

Aria Palace by OMNIA Hotels

Rome City Centre

10/10 Excellent

Ethan

A hotel with outdoor seating and a sign reading 'LEOPOLD HOTEL SAINT CHRISTOPHE BRASSERIE LEOPOLD.'

Hôtel Saint Christophe Aix en Provence Centre Ville by Germain Collection

Aix-en-Provence Historic Centre

10/10 Excellent

We had the most wonderful stay at Hôtel Saint Christophe! We were on our first visit to Aix-en-Provence for our birthdays. The hotel is perfectly situated in the Cours Mirabeau, close to all the restaurants, places of interest and even the local train and bus stations. The staff are absolutely lovely and keen to ensure you have a comfortable etay, providing information you need to get around. Breakfast is generous and really good. Loved the buttery croissants! We had a fab room looking out...

Jardin

A room with a bed, a wicker chair, a small table with two wine glasses, and a potted plant.

Palm Boutique Hôtel Nice

Nice City Centre

10/10 Excellent

susan

A building with a wooden door and windows with metal bars. There are two potted plants in front of the door.

Garlande Hotel Avignon Centre

Avignon City Centre

10/10 Excellent

The hotel Garlande is a great little hotel in the heart of Avignon. It is set in a cobbled backstreet close to the Papal Palace. The rooms are nice (we had a 3rd floor family room). It oozes charm and is quaint (we had to climb a spiral staircase to our room). The people running the hotel are amazing and are what makes this a place to defiantly visit. From discussing restaurants (and booking them for us) to advising on Provence places to visit, they couldn't do enough. The breakfasts were great,...

A rooftop terrace with outdoor seating, a dining area, and a view of historic buildings and the sea.

Hôtel Métropole Monte Carlo – Spa Guerlain

Monte Carlo

10/10 Excellent

Andrew

A balcony with a table, a hat, a glass of champagne, and strawberries.

Cavendish

Cannes City Centre

10/10 Excellent

Anonymous traveller

Find out more about Mediterranean Region

Vacation Apartments in Mediterranean Region

Search for Vacation rentals in Mediterranean Region on Expedia.! You can easily find your home rentals, villas, Vacation apartments in Mediterranean Region using one of the methods below:

View our selection of featured Vacation rentals in Mediterranean Region
Use the map to find apartments and other Vacation homes in the Mediterranean Region neighbourhood you prefer
Enter your travel dates to view the best deals on Vacation rentals in Mediterranean Region while they last

Look no further and take a look at our great range of rental properties in Mediterranean Region!

Search Holiday Rentals in Mediterranean Region

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Mediterranean Region holiday rentals

1. Varaba Country House

2. Carpe Diem Apartments By Athens Airport

3. Appart'Hotel-Restaurant Castel Emeraude

4. Masd Mediterráneo Hotel & Apartamentos

5. San Giuliano Inn - Adults Only

6. Appart'hôtel Odalys City - Monaco Les Hauts de la Principauté

7. Relais Piazza Signoria

8. Teatro Luxury Apartments Firenze - Starhotels Collezione

9. Residhome Marseille

10. Gran Hotel Guadalpin Banus

11. Ona Princesa Playa

12. Rimondi Boutique Hotels-Small Luxury Hotels of the World

13. Hu Firenze Camping In Town

14. Hôtel Soléo Prado

15. Palazzo Mannaioni Suites

16. Vila Gale Ampalius Resort Hotel

17. La Casa Del Sol Hotel

18. Nano Oia Villas

19. Residhome Nice Promenade

20. NH Marina Portimao Resort

Find holiday rentals that suit your style

Top Mediterranean Region Hotel Reviews

Only YOU Hotel Sevilla

10/10 Excellent

Find out more about Mediterranean Region

Vacation Apartments in Mediterranean Region