Mediterranean Region Packages (Flight + Hotel)

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Where to stay in Mediterranean Region

Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. Learn more about Mediterranean Region
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.

A busy urban street with historic buildings, a clock tower, and a bus.

Madrid Centro

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Puerta del Sol and Gran Via, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

A cityscape with a prominent stone wall and a view of the city below.

Lisbon City Center

Avenida da Liberdade and Rossio Square are top sights in Lisbon City Center, and you should be sure to explore the popular shops. Hop aboard the metro at Saldanha Station or Sao Sebastiao Station to see more sights in the area.

A historic cathedral with a tall bell tower and intricate architectural details.

Downtown Barcelona

Known for its fascinating museums, stunning cathedral and popular shops, there's plenty to explore in Downtown Barcelona. Top attractions like La Rambla and Plaça de Catalunya are major draws. Catch the metro at Liceu Station or Jaume I Station to see more of the city.

A classical building with columns and statues, surrounded by well-maintained hedges and a clear blue sky.

Athens City Centre

Known for its fascinating museums, charming cafes and popular shops, there's plenty to explore in Athens City Centre. Top attractions like Acropolis and Syntagma Square are major draws. Catch the metro at Panepistimio Station or Syntagma Station to see more of the city.

Top hotels in Mediterranean Region

Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
Fully refundableReserve now, pay when you stay
฿2,925
฿3,217 total
4 Oct - 5 Oct
includes taxes & fees
9.4/10 Exceptional! (1,513 reviews)
"Muy bueno nos encantó todo volvería 100 veces todo limpio fue un placer esos días en el hotel"

Reviewed on 28 Sept 2026

Hotel101- Madrid
Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
฿5,404
฿6,095 total
27 Oct - 28 Oct
includes taxes & fees
8.6/10 Excellent! (5,202 reviews)
"Stayed one night only. Room nice and clean."

Reviewed on 28 Sept 2026

Barcelona Airport Hotel
Swandor Hotels & Resort Topkapi Palace - All Inclusive

Swandor Hotels & Resort Topkapi Palace - All Inclusive

Kundu Aksu Antalya Antalya
฿7,308
฿8,112 total
29 Sept - 30 Sept
includes taxes & fees
9/10 Wonderful! (2,337 reviews)
"Excellent accommodations and great daily activities and entertainment. Food was amazing - delicious and a great variety! Our family very much enjoyed our vacation at this resort. The only critical comment is the transportation arrangement. The hotel is good about calling a taxi for you, but taxi ..."

Reviewed on 26 Sept 2026

Swandor Hotels & Resort Topkapi Palace - All Inclusive
See all 812,746 properties in Mediterranean Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mediterranean Region attractions

The Colosseum in Rome with tourists around.

Colosseum

9.4/10 (44,408 reviews)
A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.
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The Sagrada Familia with a construction crane in the foreground.

Sagrada Familia

9.4/10 (32,723 reviews)
Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires.
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A cityscape at dusk with historic buildings, a prominent Rolex store, and a busy street.
Photo by National Tourist Office of Spain

Gran Via

9.4/10 (23,455 reviews)
Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture.
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The Trevi Fountain with sculptures and a large archway.

Trevi Fountain

9.2/10 (43,482 reviews)
Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.
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A coastal cityscape at dusk with illuminated buildings, a marina, and a prominent fortress-like structure.

Port of Civitavecchia

8.6/10 (754 reviews)
Explore the waterfront in Civitavecchia with a trip to Port of Civitavecchia. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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A tree-lined street with pedestrians, buildings, and a kiosk.

La Rambla

8.8/10 (31,278 reviews)
These lively pedestrian streets in the heart of Barcelona are filled with flower stalls, tapas restaurants and street performers.
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A large neoclassical building with columns and the inscription "MAGRIPPA COSTERTIVI".

Pantheon

9.4/10 (37,189 reviews)
One of ancient Rome’s greatest achievements combines momentous history and inspired architecture.
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A historic church with twin bell towers and a central obelisk, surrounded by a crowd of people on the steps.

Spanish Steps

9.2/10 (37,743 reviews)
A monumental stairway with a monumental past, the Spanish Steps are literally and figuratively at the heart of Rome.
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