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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,075 reviews)
"Clean room, nice staff, great location in relation to Mayo Clinic"
United States
Eva
The price is ฿2,536
฿2,890 total
includes taxes & fees
23 May - 24 May
Sonesta Select Scottsdale at Mayo Clinic Campus

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
3.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,438 reviews)
"A great place to stay in all areas of comfort and ease"
United States
william
The price is ฿3,399
฿3,843 total
includes taxes & fees
24 May - 25 May
Drury Inn & Suites Phoenix Airport

Home2 Suites by Hilton Phoenix Downtown

Home2 Suites by Hilton Phoenix Downtown
3.0 star property
30.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,339 reviews)
"The location and amenities were great"
Canada
Michael
The price is ฿3,751
฿4,241 total
includes taxes & fees
29 May - 30 May
Home2 Suites by Hilton Phoenix Downtown

Hilton Phoenix Airport

Hilton Phoenix Airport
4.0 star property
25 km from Mayo Clinic
8.8 out of 10, Excellent, (1,088 reviews)
"Close to the airport and good enough."
United States
Ashley
The price is ฿2,906
฿3,286 total
includes taxes & fees
24 May - 25 May
Hilton Phoenix Airport

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice pool, affordable stay, just away from everywhere "
Canada
Charles
The price is ฿3,618
฿6,040 total
includes taxes & fees
7 May - 8 May
Wekopa Casino Resort

Hilton Garden Inn Phoenix Airport

Hilton Garden Inn Phoenix Airport
3.0 star property
27.6 km from Mayo Clinic
8.8 out of 10, Excellent, (1,002 reviews)
"Wonderful room, very clean, lovely staff"
United States
Debra
The price is ฿3,424
฿3,872 total
includes taxes & fees
23 May - 24 May
Hilton Garden Inn Phoenix Airport

SureStay By Best Western Phoenix Airport

SureStay By Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (2,046 reviews)
"Close to airport, clean and convenient"
United States
Malgorzata
The price is ฿2,763
฿3,125 total
includes taxes & fees
3 May - 4 May
SureStay By Best Western Phoenix Airport

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
2.5 star property
27.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,841 reviews)
"Very quite and clean, staff was Great, very store or restaurant you can think of with in minutes of location. "
United States
Wayne
The price is ฿3,626
฿4,099 total
includes taxes & fees
3 May - 4 May
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
23.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,089 reviews)
"Great breakfast and service.. family an I will be back! "
United States
Jeison
The price is ฿3,316
฿3,783 total
includes taxes & fees
24 May - 25 May
Hyatt Place Tempe Phoenix Airport

My Place Hotel-Phoenix East Mesa AZ

My Place Hotel-Phoenix East Mesa AZ
2.0 star property
28.2 km from Mayo Clinic
8.8 out of 10, Excellent, (181 reviews)
"The room was very clean and equipped with everything we needed. Great A/C and mini kitchen was perfect. Will stay at this location again!"
United States
Rebecca
The price is ฿3,904
฿4,461 total
includes taxes & fees
5 May - 6 May
My Place Hotel-Phoenix East Mesa AZ

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,609 reviews)
"Very nice staff and very clean food was great "
United States
Taneeka
The price is ฿5,238
฿6,899 total
includes taxes & fees
17 May - 18 May
Talking Stick Resort

Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,002 reviews)
"Friendly staff and clean, nice room!"
United States
Erica
The price is ฿2,999
฿3,424 total
includes taxes & fees
28 May - 29 May
Fountain Park Hotel, BW Signature Collection

Arizona Grand Resort & Spa

Arizona Grand Resort & Spa
4.0 star property
28.6 km from Mayo Clinic
8.6 out of 10, Excellent, (2,413 reviews)
"Great family spot for a long weekend vacation!"
United States
Danny
The price is ฿4,652
฿8,201 total
includes taxes & fees
25 May - 26 May
Arizona Grand Resort & Spa

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,387 reviews)
"Great hotel with a nice bar and restaurant. The pool was great and the rooms were clean! Fun place to stay!!"
Canada
Anthony Amos Cameron
The price is ฿6,115
฿6,970 total
includes taxes & fees
26 May - 27 May
Hotel Valley Ho

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,880 reviews)
"Great staff and location."
United States
Kathy
The price is ฿2,897
฿3,301 total
includes taxes & fees
5 May - 6 May
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.8 out of 10, Excellent, (2,725 reviews)
"Great breakfast and friendly staff"
United States
Jennifer
The price is ฿2,911
฿3,291 total
includes taxes & fees
17 May - 18 May
Hilton Garden Inn Phoenix Airport North

The Westin Tempe

The Westin Tempe
4.0 star property
22.7 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,013 reviews)
"Clean rooms, perfect location to shops and food, the staff is very kind. "
United States
Sadie
The price is ฿4,031
฿5,736 total
includes taxes & fees
21 May - 22 May
The Westin Tempe

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG
2.5 star property
20.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,012 reviews)
"Breakfast was fresh and really good and there was always parking stalls available!"
Canada
Jamie
The price is ฿3,544
฿4,007 total
includes taxes & fees
27 May - 28 May
Holiday Inn Express Hotel & Suites Phoenix North Scottsdale by IHG

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,823 reviews)
"Good breakfast, staff friendly"
Canada
shawna
The price is ฿3,482
฿3,979 total
includes taxes & fees
17 May - 18 May
Hyatt Place Phoenix/Mesa

Element Scottsdale at SkySong

Element Scottsdale at SkySong
3.0 star property
18.5 km from Mayo Clinic
9.4 out of 10, Exceptional, (828 reviews)
"Great room, very spacious and clean. Love the decor and vibe. "
United States
Analaura
The price is ฿3,121
฿3,557 total
includes taxes & fees
23 May - 24 May
Element Scottsdale at SkySong
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

East Mesa

While you're in East Mesa, take in top sights like Superstition Springs Center and jump on the metro at Superstition Springs Transit Center to see more of the city.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and Arizona Boardwalk while you're sightseeing around the area.