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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very good, (1,075 reviews)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is ฿4,124
฿4,700 total
includes taxes & fees
20 Jan - 21 Jan
Sonesta Select Scottsdale at Mayo Clinic Campus

Stay7 Studios Hotel Phoenix

Stay7 Studios Hotel Phoenix
2.0 star property
29.8 km from Mayo Clinic
7.4 out of 10, Good, (86 reviews)
"Very pleasant stay."
United States
Michelle
The price is ฿2,120
฿2,397 total
includes taxes & fees
19 Jan - 20 Jan
Stay7 Studios Hotel Phoenix

Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.6 out of 10, Excellent, (2,412 reviews)
"Great value and close to wherever we needed to go"
United States
Gabriel
The price is ฿3,710
฿4,195 total
includes taxes & fees
24 Jan - 25 Jan
Hilton Garden Inn Phoenix Airport North

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
3.0 star property
24.1 km from Mayo Clinic
8.2 out of 10, Very good, (1,827 reviews)
"Clean rooms and friendly staff. "
United States
Maria
The price is ฿3,252
฿3,716 total
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

Scottsdale Parkview Resort

Scottsdale Parkview Resort
3.5 star property
17.6 km from Mayo Clinic
8.0 out of 10, Very good, (5,215 reviews)
"Great stay, friendly staff and excellent location!"
United States
Michael Jason
The price is ฿2,917
฿3,557 total
includes taxes & fees
21 Jan - 22 Jan
Scottsdale Parkview Resort

Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix
3.0 star property
23 km from Mayo Clinic
9.0 out of 10, Wonderful, (2,119 reviews)
"Very quiet, clean, good breakfast and very courteous staff all the way around! "
United States
Candace
The price is ฿2,670
฿3,051 total
includes taxes & fees
26 Jan - 27 Jan
Days Inn & Suites by Wyndham Mesa Near Phoenix

Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
3.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,354 reviews)
"It was a great stay!"
United States
Nicholas
The price is ฿4,239
฿4,793 total
includes taxes & fees
25 Jan - 26 Jan
Drury Inn & Suites Phoenix Airport

SureStay Hotel by Best Western Phoenix Airport

SureStay Hotel by Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (1,585 reviews)
"Staff was very friendly! "
United States
Karely
The price is ฿2,487
฿2,812 total
includes taxes & fees
3 Feb - 4 Feb
SureStay Hotel by Best Western Phoenix Airport

The Azure Hotel

The Azure Hotel
2.5 star property
19.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,634 reviews)
"Rooms were clean, beds were comfy and the hotel was generally quiet. "
United States
Aaron
The Azure Hotel

Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,722 reviews)
"Friendly staff, clean room, good breakfast, and a heated pool are a plus when traveling with kids in winter. "
United States
Truong
The price is ฿4,239
฿4,844 total
includes taxes & fees
25 Jan - 26 Jan
Hyatt Place Phoenix/Mesa

Holiday Inn Express & Suites Phoenix - Airport North by IHG

Holiday Inn Express & Suites Phoenix - Airport North by IHG
2.5 star property
23.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (2,166 reviews)
"It was a good overall stay. "
United States
Vincent
The price is ฿4,208
฿4,758 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Phoenix - Airport North by IHG

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,004 reviews)
"Great place to stay. "
United States
Alexandra
The price is ฿6,142
฿7,012 total
includes taxes & fees
18 Jan - 19 Jan
Inn at Eagle Mountain

Papago Scottsdale by Reside, Trademark Collection by Wyndham

Papago Scottsdale by Reside, Trademark Collection by Wyndham
3.0 star property
18.5 km from Mayo Clinic
8.6 out of 10, Excellent, (298 reviews)
"Room was clean and service was great."
United States
Zoar
The price is ฿3,390
฿3,863 total
includes taxes & fees
25 Jan - 26 Jan
Papago Scottsdale by Reside, Trademark Collection by Wyndham

SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs
2.5 star property
23.4 km from Mayo Clinic
8.4 out of 10, Very good, (1,694 reviews)
"Room was clean and staff very pleasant. "
United States
Jovana
The price is ฿3,737
฿4,270 total
includes taxes & fees
19 Jan - 20 Jan
SureStay Plus by Best Western Mesa Superstition Springs

Sentral Sol Modern

Sentral Sol Modern
4.0 star property
29.9 km from Mayo Clinic
9.6 out of 10, Exceptional, (146 reviews)
"Friendly staff, clean room, great place and easy parking ."
United States
Steve
The price is ฿4,511
฿5,886 total
includes taxes & fees
25 Jan - 26 Jan
Sentral Sol Modern

Home2 Suites by Hilton Phoenix Downtown

Home2 Suites by Hilton Phoenix Downtown
3.0 star property
30.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,214 reviews)
"Nice locations"
United States
Milena
The price is ฿4,144
฿4,686 total
includes taxes & fees
25 Jan - 26 Jan
Home2 Suites by Hilton Phoenix Downtown

Hotel San Carlos - Downtown Convention Center

Hotel San Carlos - Downtown Convention Center
3.0 star property
30.1 km from Mayo Clinic
7.6 out of 10, Good, (1,005 reviews)
"Great stay "
United States
David
The price is ฿8,783
฿10,246 total
includes taxes & fees
17 Jan - 18 Jan
Hotel San Carlos - Downtown Convention Center

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,000 reviews)
"One of the best places I have ever stayed at. Very clean and the staff was superb."
United States
Thomas
Wekopa Casino Resort

Radisson Hotel Phoenix Airport

Radisson Hotel Phoenix Airport
3.5 star property
23.3 km from Mayo Clinic
8.6 out of 10, Excellent, (1,865 reviews)
"Clean rooms, staff and breakfast was excellent "
United States
Carlos
The price is ฿3,710
฿4,195 total
includes taxes & fees
25 Jan - 26 Jan
Radisson Hotel Phoenix Airport

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,842 reviews)
"Fantastic room, staff and breakfast!"
United States
Terry G
The price is ฿4,456
฿5,079 total
includes taxes & fees
28 Jan - 29 Jan
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Old Town

Gourmet restaurants interesting history and top sights from Western Spirit: Scottsdale's Museum of the West to Scottsdale Fashion Square – discover Old Town, a destination also famous for its shopping.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club are top sights worth seeing.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.