A riverside walkway with cyclists, a bridge, and modern buildings.

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Our top choices for Greenville hotels with a spa

A large brick house with a well-maintained garden, a welcoming entrance, and a street sign indicating the address.

1. Pettigru Place Bed & Breakfast

Pettigru Place Bed & Breakfast
3.5 star property
Greenville Downtown
10.0 out of 10, Exceptional, (143 reviews)
"The place was absolutely perfect & charming."
United States
Debbie
The price is ฿8,895
฿9,784 total
includes taxes & fees
11 Nov - 12 Nov
Pettigru Place Bed & Breakfast
A modern indoor fire feature with a stone border, surrounded by seating areas and a glass wall in the background.

2. SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown
2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1,005 reviews)
"Was a excellent stay"
United States
Deborah
The price is ฿4,750
฿5,382 total
includes taxes & fees
15 Nov - 16 Nov
SpringHill Suites by Marriott Greenville Downtown
A covered outdoor area with a grill and seating, surrounded by brick walls and windows.

3. Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1,003 reviews)
"The rooms were a great size and very friendly staff! Breakfast was great and everything was well stocked!"
United States
Cyrus
The price is ฿4,431
฿5,021 total
includes taxes & fees
24 Nov - 25 Nov
Homewood Suites by Hilton Greenville Downtown
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

4. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (570 reviews)
"Staff is friendly and very professional. I loved the location and the city very much!"
United States
Michael
The price is ฿11,748
฿13,310 total
includes taxes & fees
29 Nov - 30 Nov
Grand Bohemian Lodge Greenville, Autograph Collection
A multi-story hotel with a stone facade, large windows, and outdoor seating areas.

5. Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace
2.5 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1,003 reviews)
"Liked where it was located easy to get to shops and restaurants in walking distance"
United States
Susan
The price is ฿4,899
฿5,551 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Greenville-Downtown-RiverPlace
A hotel facade with arched windows, a fountain, and a sign for "The Westin."

6. The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1,004 reviews)
"Great location, unique history !"
United States
nadim
The price is ฿5,337
฿6,147 total
includes taxes & fees
22 Nov - 23 Nov
The Westin Poinsett Greenville
An outdoor patio with a modern design, featuring a seating area with sofas and a fire pit, surrounded by plants and under a pergola with hanging lights.

7. Residence Inn by Marriott Greenville Downtown

Residence Inn by Marriott Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (374 reviews)
"Great breakfast buffet"
United States
Lorri
The price is ฿5,347
฿6,058 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott Greenville Downtown
A modern lobby with a reception desk, seating area, and a kitchen in the background.

8. Courtyard by Marriott Greenville Downtown

Courtyard by Marriott Greenville Downtown
3.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1,001 reviews)
"nice place to stay"
United States
Ray
The price is ฿4,954
฿5,613 total
includes taxes & fees
25 Nov - 26 Nov
Courtyard by Marriott Greenville Downtown
A hotel lobby with round tables and chairs, a TV mounted on the wall, and a reception desk.

9. Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,006 reviews)
"We loved our stay here!!"
United States
Tamara
The price is ฿4,263
฿4,830 total
includes taxes & fees
29 Nov - 30 Nov
Hyatt Place Greenville Downtown
A hotel entrance with a modern design, featuring a prominent 'aloft' sign, a covered walkway, and decorative lighting.

10. Aloft by Marriott Greenville Downtown

Aloft by Marriott Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,010 reviews)
"Good location"
United States
ron
The price is ฿4,643
฿5,261 total
includes taxes & fees
22 Nov - 23 Nov
Aloft by Marriott Greenville Downtown
A multi-story hotel with a modern architectural design, featuring balconies and large windows.

11. Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace
3.5 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,001 reviews)
"Great location to walk to restaurants and bars."
United States
Casinota
The price is ฿5,202
฿5,894 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites by Hilton Greenville Downtown Riverplace
A rooftop terrace with a sofa set, chairs, a coffee table, and potted plants.

12. AC Hotel By Marriott Greenville

AC Hotel By Marriott Greenville
3.5 star property
Greenville Downtown
9.2 out of 10, Wonderful, (844 reviews)
"So nice and conveniently located"
United States
Aliyah
The price is ฿5,105
฿5,784 total
includes taxes & fees
22 Nov - 23 Nov
AC Hotel By Marriott Greenville
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

13. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (945 reviews)
"Great location-we walked to soo many shops and restaurants!"
United States
Deborah
The price is ฿3,293
฿3,622 total
includes taxes & fees
1 Dec - 2 Dec
Mint House Greenville Downtown by Kasa
An outdoor patio with seating, a fire pit, string lights, and a grill area.

14. Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1,000 reviews)
"Great staff, great location, great rooms!"
United States
Sylvia
The price is ฿4,651
฿5,117 total
includes taxes & fees
22 Nov - 23 Nov
Home2 Suites by Hilton Greenville Downtown
A hotel lobby with a reception desk, seating area, and a view of the outdoors.

15. Holiday Inn Express & Suites Greenville - Downtown by IHG

Holiday Inn Express & Suites Greenville - Downtown by IHG
2.5 star property
Greenville Downtown
9.0 out of 10, Wonderful, (1,002 reviews)
"Great service and staff. Wonderful location and very clean."
United States
James
The price is ฿4,263
฿4,689 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express & Suites Greenville - Downtown by IHG
A wooden deck with a table and chairs, a bench, and a covered area with a view of a house in the background.

16. Swamp Rabbit Inn

Swamp Rabbit Inn
3.0 star property
Greenville Downtown
8.8 out of 10, Excellent, (451 reviews)
"Amazing Property and Close to Dt Greenville!"
United States
Peyton
The price is ฿5,105
฿5,951 total
includes taxes & fees
12 Nov - 13 Nov
Swamp Rabbit Inn
A spacious lobby with a central bar area, multiple seating options, and a distinctive ceiling structure.

17. Hyatt Regency Greenville

Hyatt Regency Greenville
3.5 star property
Greenville Downtown
8.6 out of 10, Excellent, (1,003 reviews)
"Loved the location. I made these reservations months ago for 4 ladies, got to room had 3 towels, 2 face cloths and 2 hand towels. What the heck??"
United States
Deborah
The price is ฿4,536
฿5,140 total
includes taxes & fees
25 Nov - 26 Nov
Hyatt Regency Greenville
A sign for the Urban Boutique Hotel with the number 536.

18. Urban Boutique Hotel, BW Signature Collection

Urban Boutique Hotel, BW Signature Collection
2.5 star property
Greenville
8.0 out of 10, Very good, (1,005 reviews)
"The location is perfect!!! Right outside of DT and so many shopping and food options right nearby. The room was very clean and the staff were friendly and helpful. Would definitely stay here again!"
United States
Jamie
The price is ฿2,453
฿2,699 total
includes taxes & fees
15 Nov - 16 Nov
Urban Boutique Hotel, BW Signature Collection
A multi-story hotel with a yellow facade, a covered parking area, and a visible parking sign.

19. Quality Inn & Suites Greenville near downtown

Quality Inn & Suites Greenville near downtown
2.5 star property
Greenville
7.0 out of 10, Good, (794 reviews)
"It was an acceptable place to stay. It was clean."
United States
Steve
The price is ฿2,254
฿2,479 total
includes taxes & fees
30 Nov - 1 Dec
Quality Inn & Suites Greenville near downtown
A room with a bed, a dining table, a small desk, and a vintage refrigerator.

20. Tanglewood Inn

Tanglewood Inn
3.0 star property
Greenville
10.0 out of 10, Exceptional, (21 reviews)
"We absolutely loved how cozy the Inn was and Cheryl the in keeper was very friendly and helpful. The Inn is located not too far from downtown Greenville and we were easily able to commute back-and-forth when we wanted to participate in the weekend festival happening in in Greenville."
United States
Mayra
The price is ฿5,390
฿5,929 total
includes taxes & fees
22 Nov - 23 Nov
Tanglewood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Clean Great staff Good breakfast Made stay in Greenville enjoying"
Jose 4-night trip
Posted 6 hours ago
Embassy Suites Greenville Golf Resort & Conference Center

Frequently asked questions

Looking to holiday at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travellers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness centre and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 702 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas which offer services including facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.