A nighttime pedestrian bridge with illuminated railings and a rainbow-colored light projection on the floor.

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30 Oct - 1 Nov
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6 Nov - 8 Nov

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Our top choices for Greater South Side hotels

A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

1. Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,005 reviews)
"Good place to stay"
United States
Tom
The price is ฿3,101
฿3,473 total
includes taxes & fees
27 Nov - 28 Nov
Hampton Inn Des Moines-Airport
A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

2. Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,832 reviews)
"Great place to stay"
United States
Abdifatah
The price is ฿2,181
฿2,443 total
includes taxes & fees
8 Nov - 9 Nov
Days Inn & Suites by Wyndham Des Moines Airport
A restaurant with a stone wall, multiple tables, chairs, a counter, and a television.

3. Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.6 out of 10, Good, (1,003 reviews)
"Reasonable price close to airport"
United States
Barbara
The price is ฿2,190
฿2,453 total
includes taxes & fees
16 Nov - 17 Nov
Quality Inn & Suites Des Moines Airport
A reception desk with a sign reading "AmericInn" and a clock on the wall.

4. AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
3.0 star property
Greater South Side
7.8 out of 10, Good, (1,011 reviews)
"Clean, well stocked, plenty of parking, and good breakfast included."
United States
Daisy
The price is ฿2,152
฿2,411 total
includes taxes & fees
9 Nov - 10 Nov
AmericInn by Wyndham Des Moines Airport
A multi-level indoor atrium with a central pool, surrounded by seating areas and potted plants.

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.4 out of 10, Very good, (735 reviews)
"Nice location, clean facility."
United States
sandeep
The price is ฿3,849
฿4,311 total
includes taxes & fees
24 Nov - 25 Nov
Holiday Inn Des Moines-Airport/Conf Center by IHG
A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

6. Des Lux Hotel

Des Lux Hotel
3.5 star property
Court District, 3.9 km from Greater South Side
9.8 out of 10, Exceptional, (1,118 reviews)
"Friendly staff and rooms are cozy."
United States
Bobbi
The price is ฿6,047
฿6,773 total
includes taxes & fees
31 Oct - 1 Nov
Des Lux Hotel
A spacious lobby with high ceilings, large windows, and a chandelier.

7. Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 3.7 km from Greater South Side
9.6 out of 10, Exceptional, (1,403 reviews)
"Love the Bar and Restaurant also the Rooms were perfect with great staff in all locations."
United States
Christopher
The price is ฿4,210
฿4,715 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Fort Des Moines, Curio Collection by Hilton
A wooden building with a pool, a palm tree, and a sign indicating the pool's depth.

8. Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.8 out of 10, Excellent, (1,001 reviews)
"Hotel was clean and enjoyed our stay."
United States
Nancy
The price is ฿4,558
฿5,105 total
includes taxes & fees
15 Nov - 16 Nov
Des Moines Marriott Downtown
A dog lying on a bed with white bedding and a wooden headboard.

9. Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines, 3.2 km from Greater South Side
9.2 out of 10, Wonderful, (1,003 reviews)
"The staff is super friendly and supportive. Some amenities (pool) were closed due to construction. Property was clean and breakfast is always great."
United States
Joe
The price is ฿3,884
฿4,350 total
includes taxes & fees
24 Nov - 25 Nov
Holiday Inn Express & Suites Des Moines Downtown by IHG
A modern building with a sign that reads 'Staybridge Suites.' It features a mix of glass and brick facades, large windows, and a flat roof.

10. Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 4.5 km from Greater South Side
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean great stay!!!"
United States
Emily
The price is ฿3,715
฿4,161 total
includes taxes & fees
1 Nov - 2 Nov
Staybridge Suites Des Moines Downtown by IHG
An outdoor seating area with a circular fire pit, wicker furniture, and string lights.

11. Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown
3.0 star property
Court District, 3.9 km from Greater South Side
8.8 out of 10, Excellent, (691 reviews)
"Good location"
United States
Jill
The price is ฿3,387
฿3,794 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn Des Moines Downtown
Lobby lounge

12. Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel
3.5 star property
Downtown Des Moines, 4.2 km from Greater South Side
8.6 out of 10, Excellent, (1,002 reviews)
"Nice, clean hotel. Edwin, the shuttle driver, was amazing! Very personable, quick and reliable. Ordered a pork tenderloin sandwich from the hotel restaurant and it was delicious. All staff were very helpful with whatever I needed. Wouldn’t hesitate to stay here again."
United States
Valerie
The price is ฿4,288
฿4,803 total
includes taxes & fees
23 Nov - 24 Nov
Renaissance Des Moines Savery Hotel
A modern lobby with a central bar area, seating arrangements, and a distinctive ceiling design.

13. Hilton Des Moines Downtown

Hilton Des Moines Downtown
3.5 star property
Downtown Des Moines, 4.5 km from Greater South Side
9.0 out of 10, Wonderful, (1,004 reviews)
"Best location for any event at the Casey’s center. Walking distance to great food. Easy walk to events. Hotel is great"
United States
Brent
The price is ฿4,487
฿5,176 total
includes taxes & fees
15 Nov - 16 Nov
Hilton Des Moines Downtown
A modern dining area with a large island table, multiple chairs, and a chandelier.

14. Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown
2.5 star property
Court District, 3.9 km from Greater South Side
8.6 out of 10, Excellent, (1,006 reviews)
"Friendly staff and decent breakfast."
United States
Kristy
The price is ฿3,572
฿4,000 total
includes taxes & fees
2 Nov - 3 Nov
Hampton Inn & Suites Des Moines Downtown
An outdoor patio area with tables and chairs, a fire pit, and string lights.

15. Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown
4.0 star property
Downtown Des Moines, 4.8 km from Greater South Side
9.0 out of 10, Wonderful, (539 reviews)
"Great location to all of downtown"
United States
CINDY
The price is ฿3,239
฿3,627 total
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott Des Moines Downtown
A spacious lounge area with a sofa set, a pool table, and large windows offering views of the street.

16. Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection
4.0 star property
Court District, 3.8 km from Greater South Side
9.4 out of 10, Exceptional, (1,000 reviews)
"Conveniently located well appointed property. Staff were very helpful."
Australia
Brett
The price is ฿5,134
฿5,750 total
includes taxes & fees
26 Nov - 27 Nov
Surety Hotel, Autograph Collection
A multi-level hotel lobby with a central water feature, multiple floors, and a seating area with a sofa and table.

17. Embassy Suites by Hilton Des Moines Downtown

Embassy Suites by Hilton Des Moines Downtown
3.5 star property
Historic East Village, 4.4 km from Greater South Side
8.4 out of 10, Very good, (1,011 reviews)
"First time at this hotel in Des Moines downtown. Entire experience was wonderful. The morning breakfast was the best we have ever had from a hotel stay. Within walking distance of everything we wanted to do downtown."
United States
Patty
The price is ฿4,402
฿4,930 total
includes taxes & fees
8 Nov - 9 Nov
Embassy Suites by Hilton Des Moines Downtown
A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

18. Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines, 4.9 km from Greater South Side
8.8 out of 10, Excellent, (1,015 reviews)
"Another great stay as usual!"
United States
Thomas
The price is ฿3,128
฿3,504 total
includes taxes & fees
9 Nov - 10 Nov
Comfort Inn & Suites Event Center
A multi-story hotel with a classic brick facade, large windows, and a prominent Liberty Building sign.

19. Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.2 out of 10, Very good, (1,010 reviews)
"The breakfast was very good and so were the bed and linens. Very nice fitness center and pool very friendly staff!"
United States
dinah
The price is ฿3,714
฿4,160 total
includes taxes & fees
8 Nov - 9 Nov
Hyatt Place Des Moines/Downtown
An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

20. Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 5.6 km from Greater South Side
9.4 out of 10, Exceptional, (1,007 reviews)
"Super comfy bed breakfast wasnt bad lots of options"
United States
Cassandra
The price is ฿3,128
฿3,504 total
includes taxes & fees
11 Nov - 12 Nov
Home2 Suites by Hilton Des Moines at Drake University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Greater South Side

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious hotel lobby with a central bar, seating area, and a ceiling fan.
Hampton Inn Des Moines-Airport
2.5 star property
8.8
Excellent
1,005 reviews
View
A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.
Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
8.6
Excellent
1,832 reviews
View
A multi-level indoor atrium with a central pool, surrounded by seating areas and potted plants.
Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
8.4
Very good
735 reviews
View
A reception desk with a sign reading "AmericInn" and a clock on the wall.
AmericInn by Wyndham Des Moines Airport
3.0 star property
7.8
Good
1,011 reviews
View
A restaurant with a stone wall, multiple tables, chairs, a counter, and a television.
Quality Inn & Suites Des Moines Airport
2.5 star property
7.6
Good
1,003 reviews
View

Where to stay in Greater South Side

Find the best Greater South Side areas for the activities you enjoy most.
The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

A sign reading "Historic East Village" with a clear blue sky and clouds in the background.

Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

A city skyline at night with illuminated buildings and a prominent tower.
Photo by Ryan Brohm
Open Photo by Ryan Brohm

Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Science Center of Iowa and Principal Park while you're in town.

The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.
Photo by Eric Mondres
Open Photo by Eric Mondres

Drake

While visiting Drake, you might make a stop by sights like Knapp Center and Des Moines Community Playhouse.

A city skyline at dusk with illuminated buildings, a bridge, and a river.

Beaverdale

While Beaverdale isn't home to many top sights, Merle Hay Mall and Knapp Center are some notable places to visit nearby.

Top Greater South Side Hotel Reviews

AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

8/10 Good
"It was ok"
Leonel 2-night trip
Posted 1 hour ago
AmericInn by Wyndham Des Moines Airport

Frequently asked questions

What's it like in Greater South Side?
Travellers are sure to enjoy a stay in Des Moines's Greater South Side neighbourhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
What's the best accommodation in Greater South Side?
Based on our traveller data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighbourhood include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport.
How many hotels can I expect to find in Greater South Side?
With 17 Expedia hotels and other accommodation options in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Greater South Side.
What is there to do around this Des Moines neighbourhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.