The Best Hotels in Central San Mateo, San Francisco - 2026 Updated Prices

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Where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.

A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

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Top Central San Mateo Hotel Reviews

Chancellor Hotel on Union Square

10/10 Excellent

"From the moment of stepping into the hotel, the staff was welcoming, helpful and friendly... check in, bell hop and bartender at the on site bar. The room, although small, was pristine and well appointed with amenities, even the little rubber duckie in the shower/bathtub. The walk in closet is a nice touch to keep luggage and clothing out of sight and out of the way. The bed was super comfortable, the room was quiet despite the hotel being just off of Union Square and steps away from the cable cars coming and going. I enjoyed my stay so much that I have 2 more stays booked for next month"

Hotel Nikko San Francisco

10/10 Excellent

"I had a truly wonderful stay, and I would like to express my sincere appreciation to the entire Front Office team (Craig) and also to Esteban from the breakfast staff. From the moment we arrived until the day we checked out, the Front Office staff made us feel genuinely welcome. Their warmth, professionalism, efficiency, and willingness to help with every request made our stay effortless and memorable. Every interaction was handled with kindness and a genuine smile. Thank you guy!!!"

Hotel Riu Plaza Fisherman's Wharf

8/10 Good

"Room: B The hotel room was a decent size with 2 queen beds and a little sitting area with a couch. The bed was a little firm to my liking and my wife noticed the left side had a little dip. The air conditioning was a little loud, but luckily we are heavy sleepers. The TV only had a few channels but we didn’t really spend a lot of time in the room. It was comfortable enough for a few nights stay. Amenities: A The toiletries were standard, the gym was small (weights maxed at 50lbs, cardio machines, and a broken cable machine), and the pool was nice for when the sun came out briefly. Parking is a bit tight if you have a tall car so make sure it’s under 6ft. Very average I would say for most of the amenities. BUT the best part of the hotel was the breakfast buffet. A FULL breakfast - bacon, sausage, eggs, hash browns, pancakes, bagels, pastries, deli meats, fruits, granola, oatmeal, cereals, coffee, juices, several milk choices, and even toasters for the bagels/bread - made it worth it. Not having to worry about feeding my family in the morning made it so much easier to start our day off right. That alone made my overall stay a good one."

Parc 55 San Francisco - A Hilton Hotel

10/10 Excellent

"The stay at this hotel was second to none in every category. The staff was very friendly and very professional and they went above and beyond to make sure our stay was as good as possible. Maria was very kind and friendly and I highly recommend that someone recognize her as the best agent on the staff. The concierge was very helpful and she was extremely nice handling all of our concerns and information about the city. The hotel restaurant was excellent and the hostess was a very kind person. I’m very grateful for their hospitality and attitude towards the guests who are staying in their hotel."

Frequently asked questions

What is Central San Mateo like?

You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.

What's a favourite place to stay in Central San Mateo?

Based on Expedia customer reviews, Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG is the highest ranked property in Central San Mateo. This hotel offers a restaurant and a 24-hour fitness centre.

How many hotels will I find in the Central San Mateo area?

Expedia has 37 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.

If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.

What is there to do in this San Mateo neighbourhood?

A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Poplar Creek Golf Course and San Mateo County Event Center are a couple of additional sights to visit in San Mateo.

How can I get around Central San Mateo and the greater San Mateo area?

If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.

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Our top choices for Central San Mateo hotels

1. @ Marbella Lane - Bright and Cozy Home Near SFO

2. Sanmateo Cozy Central 3b1b Home Garage Parking AC

3. Hampton Inn & Suites San Mateo-San Francisco Airport

4. Best Western Inn & Suites San Mateo - San Francisco Airport

5. Hilton San Francisco Airport Bayfront

6. Embassy Suites by Hilton San Francisco Airport Waterfront

7. Aloft by Marriott San Francisco Airport

8. Bay Landing San Francisco Airport Hotel

9. Hyatt Regency San Francisco Airport

10. DoubleTree by Hilton San Francisco Airport

11. Crowne Plaza San Francisco Airport by IHG

12. The Dylan at SFO

13. La Quinta Inn & Suites by Wyndham San Francisco Airport West

14. Hotel Aura SFO

15. Hotel 1550 - SFO Airport

16. Embassy Suites by Hilton San Francisco Airport Oyster Point

17. Best Western Plus Grosvenor Airport Hotel

18. The Millwood - A Boutique Hotel

19. Hotel Skye SFO

20. DoubleTree by Hilton San Francisco South Airport Blvd

Where to stay in Central San Mateo

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Central San Mateo Hotel Reviews

Chancellor Hotel on Union Square

Frequently asked questions

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