Lake City Holiday Rentals, South Carolina: Private House Rentals

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Our top choices for Lake City hotels

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.

A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.

A spacious living room with hardwood flooring, a staircase, and a large window.

1. The Inn at the Crossroads

Lake City

Paige

฿3,897

฿4,365 total

includes taxes & fees

28 Oct - 29 Oct

A spacious lobby with a chandelier, seating area, and a reception desk.

A hotel room with a bed, a sofa, a desk, and a chair.

A spacious lobby with a chandelier, sofas, a reception desk, and a large window.

A conference room with a dark table and chairs, a vase with white flowers, and large windows with white trim.

2. Quality Inn & Suites Lake City

Lake City

Vajannise

฿3,472

฿3,889 total

includes taxes & fees

5 Nov - 6 Nov

A spacious lobby with a large seating area, a decorative ceiling light, and a view of the outdoors.

A living room with a sofa, chairs, a coffee table, a cabinet, and decorative items.

A brick building with a stone pillar, large potted plants, and a wreath on the door.

3. Days Inn by Wyndham Lake City

Lake City

BRIANNA

฿3,281

฿3,675 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a reception desk, seating area, and a television screen.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

4. Comfort Inn & Suites Florence Center Area

Florence

Mila

฿3,395

฿3,803 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.

A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.

A coffee station with two coffee machines and a display of coffee pods and cups.

5. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

฿3,827

฿4,286 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, glass doors, and a number '501' above.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

6. Fairfield Inn & Suites by Marriott Florence I-20

Florence

Alma

฿3,966

฿4,442 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.

A modern lobby with a round table, sofas, and a reception desk.

7. Homewood Suites by Hilton Florence

Florence

Aekyung

฿3,538

฿4,295 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A conference room with round tables, chairs, and a carpeted floor.

8. Staybridge Suites Florence - Civic Center by IHG

Florence

Tishia

฿4,532

฿5,075 total

includes taxes & fees

1 Nov - 2 Nov

A reception area with a wooden counter, brown leather seating, and a chandelier.

A dining area with tables and chairs, large windows, and a television on a wooden cabinet.

A hotel room with a desk, two lamps, a television, a chair, and a large mirror.

A hotel room with a large bathtub, a bed with a headboard, two bedside tables with lamps, and a patterned rug.

9. Quality Inn Kingstree North

Kingstree

Robert

฿2,425

฿2,716 total

includes taxes & fees

11 Nov - 12 Nov

A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

An indoor swimming pool with lounge chairs and exercise equipment.

A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

10. Home2 Suites by Hilton Florence, SC

Florence

saleh

฿3,710

฿4,356 total

includes taxes & fees

3 Nov - 4 Nov

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

A modern lounge area with a sofa, armchairs, and small tables.

11. TownePlace Suites by Marriott Florence

Florence

Crystal

฿3,681

฿4,122 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

A hotel with a modern design, featuring multiple floors and a parking lot.

12. Residence Inn Marriott Florence

Florence

Teri

฿3,733

฿4,181 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

A hotel lobby with a reception desk, seating area, and a welcome mat.

13. Hampton Inn & Suites Florence Center

Florence

Ryan

฿3,823

฿4,282 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

14. SpringHill Suites by Marriott Florence

Florence

John

฿3,403

฿4,011 total

includes taxes & fees

31 Oct - 1 Nov

A spacious lobby with a reception desk, seating area, and large windows.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

15. Hilton Garden Inn Florence

Florence

Derrick

฿3,966

฿4,442 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A swimming pool with lounge chairs and a building with balconies.

16. Quality Inn & Suites Florence Civic Center

Florence

Sharhonda

฿2,966

฿3,322 total

includes taxes & fees

20 Oct - 21 Oct

A modern building with a covered parking area, a well-maintained lawn, and a clear sky.

A bathroom with a shower, toilet, and a towel rack.

A modern building with a covered entrance, a parking area, and a well-maintained lawn.

A hotel room with two beds, a nightstand, a chair, and a wall-mounted lamp.

17. Budget Inn Timmonsville

Timmonsville

Bethany

฿2,047

฿2,293 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

A modern lounge area with a pool table, sofas, and yellow chairs.

A modern kitchen with a white countertop, three black stools, and a red accent wall.

18. Aloft by Marriott Florence

Florence

SARAH

฿3,733

฿4,380 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a TV mounted on the wall, and a bathroom visible through an open door.

A row of brick buildings with orange doors and windows, a covered walkway, and a parking area.

A bathroom with a white sink, mirror, and a bathtub.

A room with orange walls, a blue sofa, a wooden cabinet, and a window with a view.

19. Hotel O Deluxe Inn Kingstree Sc Hwy 52

Kingstree

Nick

฿2,403

฿2,932 total

includes taxes & fees

15 Oct - 16 Oct

A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.

A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and a balcony with outdoor seating.

A hotel room with two beds, a desk, a chair, and a TV.

A modern bar area with a counter, stools, and tables.

20. Courtyard by Marriott Florence

Florence

Willie

฿3,253

฿3,843 total

includes taxes & fees

25 Oct - 26 Oct

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Stay near popular Lake City attractions

The Country Club at Lake City

7.4/10 (34 reviews)

This championship golf course designed by Willard Byrd has hosted prestigious PGA events. Members and their guests enjoy the challenging par-72 layout amid natural landscapes with full pro shop amenities.

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Lions Park

7.6/10 (19 reviews)

Lions Park offers a community-focused recreational space with new pickleball and tennis courts around an enlarged lake. Visitors can enjoy outdoor activities as the park undergoes enhancements.

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Lynches Lake Historical Society

7.2/10 (9 reviews)

This intimate museum chronicles the Pee Dee region's Revolutionary War history and Native American heritage. Explore well-curated exhibits showcasing colonial artefacts and early trades during weekday visits.

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The Bean Market

8.4/10 (27 reviews)

This historic 1936 venue was once the world's largest string bean market. Today it houses a museum celebrating agricultural heritage while hosting weddings and community events in its rustic brick-and-beam interior.

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Moore Farms Botanical Garden

8.0/10 (9 reviews)

This 50-acre botanical masterpiece blends innovative displays with South Carolina's pastoral beauty. Explore over 5,000 plant varieties and climb the fire tower for panoramic views of the meticulously curated landscape.

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Ronald E. McNair Life History Center

8.4/10 (26 reviews)

This intimate museum honours Lake City native Dr. Ronald McNair, astronaut and physicist who died in the Challenger disaster. View artefacts tracing his journey from small-town beginnings to space exploration.

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Learn more about Lake City

Stroll through Moore Farms Botanical Garden's lush landscapes, where seasonal blooms and tranquil paths await. Dive into local history at the Bean Market, a restored 1930s tobacco warehouse now hosting community events and showcasing regional culture.

See all hotels in Lake City

a great blue heron in a South Carolina swamp during fall

Top Lake City Hotel Reviews

Comfort Inn & Suites Florence Center Area

10/10 Excellent

"Parking was great, The room was very clean.The Staff was very kind,patient and Friendly. The breakfast area was very clean, The breakfast was not replenished with the eggs and sausage when we went for breakfast but we were able to eat some muffins and danishes"

Aloft by Marriott Florence

8/10 Good

"The room we stayed in was overall. A 6 out of a 10, the shower leaked out of the glass. Door could use some updates. Some new cy"

The Inn at the Crossroads

8/10 Good

"The room was nice ok not spectacular. The bed was way way too soft. The rooms does not have microwave ovens. And I had no choice this time so I stayed there. It was on the weekend nearly $300 that room was not worth $300. Next time I will plan better and stay in Florence. $600 for two rooms for 1 nights. I will not book again. The front desk employee was very pleasant."

Quality Inn & Suites Florence Civic Center

8/10 Good

"Very helpful staff! Great! Some of the exterior is showing age, but overall, a great value and easy location. The room was nice and roomy and very clean."

Days Inn by Wyndham Lake City

8/10 Good

"Our stay was good for just one night. The room was surprisingly very nice and cozy. The outside of it isn't spectacular but the hotel was nice. The only downside was after our evening we saw a few ants in the tub, didn't know where they were coming from. However, they disappeared and went somewhere else. The shower was nice and the water was spectacular temperature. Thanks for a great stay. We didn't get to have any breakfast with them because we left early the next morning. We would stay here again."

Fairfield Inn & Suites by Marriott Florence I-20

10/10 Excellent

"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"

More cheap stays in Lake City

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC

฿2,182

฿2,444 total

15 Oct - 16 Oct

includes taxes & fees

7.2/10 Good! (1,002 reviews)

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

฿2,966

฿3,322 total

20 Oct - 21 Oct

includes taxes & fees

8.4/10 Very good! (391 reviews)

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

฿3,395

฿3,803 total

8 Nov - 9 Nov

includes taxes & fees

9/10 Wonderful! (1,373 reviews)

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC

฿3,823

฿4,282 total

1 Nov - 2 Nov

includes taxes & fees

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

3440 W Radio Dr Florence SC

฿3,827

฿4,286 total

18 Oct - 19 Oct

includes taxes & fees

The Inn at the Crossroads

128 West Main Street Lake City SC

฿3,897

฿4,365 total

28 Oct - 29 Oct

includes taxes & fees

9.4/10 Exceptional! (1,003 reviews)

Frequently asked questions

What's the best place for a stay in Lake City?

Based on our traveller data, The Inn at the Crossroads is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Other good choices for your trip include Quality Inn & Suites Lake City and Days Inn by Wyndham Lake City. See all available top hotels, or vacation rentals in Lake City.

If I need to cancel my hotel reservation in Lake City, will I receive a refund?

Yes, most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Lake City.

What is the top LGBTQ-friendly accommodation in Lake City?

The Inn at the Crossroads is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Lake City.

What's the best dog-friendly accommodation option in Lake City?

Days Inn by Wyndham Lake City is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Lake City.

What are some accommodation options with pools in Lake City?

Days Inn by Wyndham Lake City: Provides daily, a seasonal outdoor pool and free self parking. Comfort Inn & Suites Florence Center Area and Quality Inn & Suites Florence Civic Center are a couple of other choices that offer an on-site pool. View all hotels with pools in Lake City.

What is staying in Lake City like?

Visitors to Lake City will definitely enjoy the lakeside setting and restaurants. Tourists can also enjoy the city's shopping and parks. In Lake City, there are 4 hotels and other accommodation options to choose from. Find out more about Lake City.

What is there to see in Lake City?

Natural beauty is on display at Lions Park, Ronald E. McNair Life History Center and Moore Farms Botanical Garden. A couple of additional sights to add to your itinerary are The Country Club at Lake City and Lynches Lake Historical Society. Take a look at what more there is to see and do in Expedia's Lake City guide.

What's the weather like in Lake City?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Lake City is 1354 mm.

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Book Hotels in Lake City on Expedia.com

Find hotels in Lake City, SC from ฿1,996

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Lake City

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lake City hotels

1. The Inn at the Crossroads

2. Quality Inn & Suites Lake City

3. Days Inn by Wyndham Lake City

4. Comfort Inn & Suites Florence Center Area

5. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

6. Fairfield Inn & Suites by Marriott Florence I-20

7. Homewood Suites by Hilton Florence

8. Staybridge Suites Florence - Civic Center by IHG

9. Quality Inn Kingstree North

10. Home2 Suites by Hilton Florence, SC

11. TownePlace Suites by Marriott Florence

12. Residence Inn Marriott Florence

13. Hampton Inn & Suites Florence Center

14. SpringHill Suites by Marriott Florence

15. Hilton Garden Inn Florence

16. Quality Inn & Suites Florence Civic Center

17. Budget Inn Timmonsville

18. Aloft by Marriott Florence

19. Hotel O Deluxe Inn Kingstree Sc Hwy 52

20. Courtyard by Marriott Florence

Stay near popular Lake City attractions

The Country Club at Lake City

Lions Park

Lynches Lake Historical Society

The Bean Market

Moore Farms Botanical Garden

Ronald E. McNair Life History Center

Learn more about Lake City

Top Lake City Hotel Reviews

Comfort Inn & Suites Florence Center Area

Aloft by Marriott Florence

The Inn at the Crossroads

Quality Inn & Suites Florence Civic Center

Days Inn by Wyndham Lake City

Fairfield Inn & Suites by Marriott Florence I-20

More cheap stays in Lake City

Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites Florence Civic Center

Comfort Inn & Suites Florence Center Area

Hampton Inn & Suites Florence Center

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

The Inn at the Crossroads

Frequently asked questions

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