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Check prices for these dates

Tonight
26 Feb - 27 Feb
Tomorrow
27 Feb - 28 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

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Our top choices for Santa Cruz hotels

Outdoor pool

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
The price is ฿1,709
฿1,709 total
27 Feb - 28 Feb
AMERICA APARTMENTS
Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (346 reviews)
"Awesome place "
Canada
John
The price is ฿3,020
฿3,020 total
28 Feb - 1 Mar
Sun Hotel
Lobby sitting area

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (107 reviews)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ฿3,263
฿3,263 total
18 Mar - 19 Mar
Novotel Santa Cruz De La Sierra
Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (362 reviews)
"Welcoming clean rooms, friendly staff, continental breakfast with natural drinks "
United States
Victor
The price is ฿4,071
฿4,071 total
29 Mar - 30 Mar
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (263 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ฿2,287
฿2,287 total
7 Mar - 8 Mar
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool, pool umbrellas, pool loungers

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (215 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ฿3,302
฿3,302 total
27 Mar - 28 Mar
Marriott Santa Cruz de la Sierra Hotel
Outdoor pool, pool loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (125 reviews)
"The staff and property are second to none! "
United States
Cynthia
The price is ฿3,803
฿3,803 total
14 Mar - 15 Mar
Hotel Cortez
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (90 reviews)
"Amazing breakfast "
United States
Sergio
The price is ฿1,535
฿1,535 total
27 Feb - 28 Feb
Ibis Santa Cruz DE LA Sierra
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (86 reviews)
"Good price, great hotel!"
United States
James
The price is ฿1,212
฿1,212 total
27 Feb - 28 Feb
Premium Suites Deluxe Aparthotel Equipetrol
1 bedroom, in-room safe, desk, iron/ironing board

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (99 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz
Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (420 reviews)
"Rooms were very clean and service was excellent "
United States
JESUS
The price is ฿3,759
฿3,759 total
1 Mar - 2 Mar
Camino Real Hotel
Standard Room, 2 Single Beds | Premium bedding, minibar, in-room safe, desk

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (284 reviews)
"Awesome hotel "
Canada
John
Hotel LP Santa Cruz Centro
Double Room, 1 Queen Bed | Premium bedding, down duvets, minibar, blackout curtains

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105 reviews)
"Excelente Hotel "
Mexico
JACOB
Hotel G
Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (43 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ฿2,097
฿2,097 total
27 Feb - 28 Feb
HOTEL OSHO
Daily buffet breakfast (USD 10 per person)

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (202 reviews)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol
Bar (on property)

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (90 reviews)
"Easy to access"
United States
Dorothy
The price is ฿1,613
฿1,613 total
28 Feb - 1 Mar
Terranova Suites
Dining room

Hotel BY Armonia SCZ

Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very good, (7 reviews)
"Very beautiful grounds. They were very responsive and accommodating. I enjoyed the hotel very much. "
United States
Kaerlig
Hotel BY Armonia SCZ
View from property

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ฿2,139
฿2,139 total
3 Mar - 4 Mar
Hotel Continental Park
Exterior detail

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (152 reviews)
"Yes! Room was spotless. The staff are very patient and professional. "
United States
Pluetina
The price is ฿3,076
฿3,076 total
27 Feb - 28 Feb
TRYP by Wyndham Santa Cruz
Massages

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (84 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ฿3,909
฿3,909 total
13 Mar - 14 Mar
Swissôtel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Holiday Rentals in Santa Cruz

Aparthotel
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace
Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (12 reviews)
"Perfect hotel"
Equipetrol Suites Apart Hotel
See all holiday rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

4.4/5 (70 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
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San Lorenzo Cathedral which includes a church or cathedral and interior views

San Lorenzo Cathedral

4.5/5 (36 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent
"Lovely staff. Great buffets. "
Amanda 3-night trip
Posted 3 days ago
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
The price is ฿1,737 per night from 28 Mar to 29 Mar
฿1,737
฿1,737 total
28 Mar - 29 Mar

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a favourite with Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Alfonsina Hotel Boutique by Inboccaluppo and Lido Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Urubo Suite - Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
HOTEL OSHO is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Prince Hotel. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 286 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Ethno-folkloric Museum and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Arenal Park and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.