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Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

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Our top choices for Santa Cruz hotels

Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (378 reviews)
"Very close to the airport Room is so quiet and comfortable "
United States
yong
The price is ฿3,525
฿3,525 total
29 May - 30 May
Sun Hotel
Outdoor pool, pool loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (138 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ฿3,495
฿3,495 total
30 May - 31 May
Hotel Cortez
Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (378 reviews)
"Nice hotel"
United States
Mabel Marisel
The price is ฿4,133
฿4,133 total
12 Jun - 13 Jun
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (275 reviews)
"Convenient location clean rooms good breakfast with a view "
Canada
Jesus Enrique Cabello
The price is ฿3,051
฿3,051 total
9 Jun - 10 Jun
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (426 reviews)
"Good property the great amenities and service"
United States
James
The price is ฿5,146
฿5,146 total
12 Jun - 13 Jun
Camino Real Hotel
Living area

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
7.8 out of 10, Good, (7 reviews)
"They nevershow up for let me in, i call many times and after 5 or 6 calls they answer saying someone going to be there in 15 for let me in. I wait 25 minutes and not body came. I went to other hotel because this is just regular house. No happy with this "hotel" im giving one because dont allow me to put -5 stars. "
United States
Nico
The price is ฿1,469
฿1,615 total
29 May - 30 May
Posada Express Fast Check
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
United States
Blanca
The price is ฿1,273
฿1,273 total
31 May - 1 Jun
Premium Suites Deluxe Aparthotel Equipetrol
Outdoor pool, pool umbrellas, pool loungers

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (233 reviews)
"Amazing hotel"
United States
Deivis
The price is ฿3,613
฿3,613 total
12 Jun - 13 Jun
Marriott Santa Cruz de la Sierra Hotel
Honeymoon Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ฿1,504
฿1,993 total
29 May - 30 May
HOTEL OSHO
Exterior detail

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (161 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
The price is ฿3,231
฿3,231 total
29 May - 30 May
TRYP by Wyndham Santa Cruz
Double Room, 1 Queen Bed | Premium bedding, down duvets, minibar, blackout curtains

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ฿1,171
฿1,171 total
27 Jun - 28 Jun
Hotel G
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (131 reviews)
"Wonderful staff, great food, big bathroom, just wonderful"
Canada
John
The price is ฿2,573
฿2,573 total
19 Jun - 20 Jun
Cosmopolitano Hotel Boutique
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (67 reviews)
"Clean and close to the malls and restaurants "
United States
Luis
The price is ฿1,762
฿1,762 total
30 May - 31 May
Chairú Eco Hotel
Massages

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ฿4,830
฿4,830 total
22 Jun - 23 Jun
Swissôtel Santa Cruz De La Sierra
Lobby sitting area

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (115 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is ฿4,086
฿4,086 total
16 Jun - 17 Jun
Novotel Santa Cruz De La Sierra
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (118 reviews)
"Nice place"
United States
Juan Carlos
The price is ฿1,939
฿1,939 total
29 May - 30 May
Ibis Santa Cruz DE LA Sierra
Exterior

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ฿734
฿734 total
1 Jun - 2 Jun
Surbackpackers
View from property

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.6 out of 10, Excellent, (26 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ฿2,247
฿2,247 total
29 May - 30 May
Hotel Continental Park
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is ฿1,622
฿1,622 total
31 May - 1 Jun
Equipetrol Suites Apart Hotel
Outdoor pool

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (93 reviews)
"Rooms are always spotless good breakfasts rooftop pool with decent view "
Canada
Peter
The price is ฿1,730
฿1,730 total
29 May - 30 May
Delfines Collection Hotel By Mercure
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Holiday Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
Premium Suites Deluxe Aparthotel Equipetrol
See all holiday rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

4.4/5 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

10/10 Excellent
"This is the perfect hotel to stay at while staying in Santa Cruz…look no further because everything was perfect!!! Very hospitable, kind, and understanding. Room was affordable and within distance of everything and very nice!!! Highly recommend your stay while in Santa Cruz. Sending love from Los Angeles 🇲🇽 and Rio de Janeiro 🇧🇷"
Crystal 2-night trip
Posted less than an hour ago
Premium Suites Deluxe Aparthotel Equipetrol

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
The price is ฿1,622 per night from 31 May to 1 Jun
฿1,622
฿1,622 total
31 May - 1 Jun

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Sun Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Travelero Hostel ans Tours and Residencial Ikandire II. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and HOTEL OSHO. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 289 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Sacred Art Museum and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.