Effingham Holiday Rentals, South Carolina: Private House Rentals

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Our top choices for Effingham hotels

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A coffee station with two coffee machines and a display of coffee pods and cups.

A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

฿3,827

฿4,286 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

2. Comfort Inn & Suites Florence Center Area

Florence

Mila

฿3,395

฿3,803 total

includes taxes & fees

8 Nov - 9 Nov

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

3. Hyatt Place Florence Downtown

Florence

Ivette

฿3,357

฿3,759 total

includes taxes & fees

3 Nov - 4 Nov

A hotel entrance with a stone facade, glass doors, and a number '501' above.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

4. Fairfield Inn & Suites by Marriott Florence I-20

Florence

Alma

฿3,966

฿4,442 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.

A modern lounge area with a fireplace, comfortable seating, and a decorative wall.

A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

5. Homewood Suites by Hilton Florence

Florence

Aekyung

฿3,538

฿4,295 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A conference room with round tables, chairs, and a carpeted floor.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

6. Staybridge Suites Florence - Civic Center by IHG

Florence

Tishia

฿4,532

฿5,075 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

7. SpringHill Suites by Marriott Florence

Florence

John

฿3,403

฿4,011 total

includes taxes & fees

31 Oct - 1 Nov

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

A hotel with a modern design, featuring multiple floors and a parking lot.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

8. Residence Inn Marriott Florence

Florence

Teri

฿3,733

฿4,181 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

An indoor swimming pool with lounge chairs and exercise equipment.

A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

9. Home2 Suites by Hilton Florence, SC

Florence

saleh

฿3,710

฿4,356 total

includes taxes & fees

3 Nov - 4 Nov

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

10. TownePlace Suites by Marriott Florence

Florence

Crystal

฿3,681

฿4,122 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

11. Hilton Garden Inn Florence

Florence

Derrick

฿3,966

฿4,442 total

includes taxes & fees

8 Nov - 9 Nov

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

12. Hampton Inn & Suites Florence Center

Florence

Ryan

฿3,823

฿4,282 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

13. Park Inn by Radisson Florence, SC

Florence

Juan

฿2,998

฿3,357 total

includes taxes & fees

1 Nov - 2 Nov

A restaurant with brick walls, framed awards, and a bar area.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

14. Hotel Florence, Tapestry Collection by Hilton

Florence

Ankh

฿3,978

฿4,455 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

15. Tru by Hilton Florence I-95

Florence

Tiffany

฿3,402

฿4,010 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

A modern kitchen with a white countertop, three black stools, and a red accent wall.

A bar area with a neon sign, shelves of bottles, and a view of trees through large windows.

A modern lounge area with a pool table, sofas, and yellow chairs.

16. Aloft by Marriott Florence

Florence

SARAH

฿3,733

฿4,380 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A swimming pool with lounge chairs and a building with balconies.

17. Quality Inn & Suites Florence Civic Center

Florence

Sharhonda

฿2,966

฿3,322 total

includes taxes & fees

20 Oct - 21 Oct

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

18. Howard Johnson by Wyndham Florence

Florence

HOMERO

฿2,168

฿2,429 total

includes taxes & fees

15 Oct - 16 Oct

A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.

An indoor swimming pool with clear water, surrounded by tiled walls and a wooden floor. There are chairs and a table near the pool, and large windows allow natural light to enter.

A modern bar area with a counter, stools, and tables.

A hotel room with two beds, a desk, a chair, and a TV.

19. Courtyard by Marriott Florence

Florence

Willie

฿3,253

฿3,843 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

20. Spark by Hilton Florence North I-95, SC

Florence

Tienia

฿2,825

฿3,296 total

includes taxes & fees

2 Nov - 3 Nov

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Top Effingham Hotel Reviews

Comfort Inn & Suites Florence Center Area

10/10 Excellent

"Parking was great, The room was very clean.The Staff was very kind,patient and Friendly. The breakfast area was very clean, The breakfast was not replenished with the eggs and sausage when we went for breakfast but we were able to eat some muffins and danishes"

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"It was perfect for us. We just needed a place to spend the night. It’s a halfway point for a long hour trip for us. We’ll make that trip several times a year and will stop here. It’s great."

Park Inn by Radisson Florence, SC

10/10 Excellent

"All around good value as a late model hotel with everything functional."

Aloft by Marriott Florence

8/10 Good

"The room we stayed in was overall. A 6 out of a 10, the shower leaked out of the glass. Door could use some updates. Some new cy"

The Inn at the Crossroads

8/10 Good

"The room was nice ok not spectacular. The bed was way way too soft. The rooms does not have microwave ovens. And I had no choice this time so I stayed there. It was on the weekend nearly $300 that room was not worth $300. Next time I will plan better and stay in Florence. $600 for two rooms for 1 nights. I will not book again. The front desk employee was very pleasant."

Quality Inn & Suites Florence Civic Center

8/10 Good

"Very helpful staff! Great! Some of the exterior is showing age, but overall, a great value and easy location. The room was nice and roomy and very clean."

Super 8 by Wyndham Florence

8/10 Good

"."

Howard Johnson by Wyndham Florence

10/10 Excellent

"Excellent hotel! Will stay again."

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

8/10 Good

"Good"

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

฿2,168

฿2,429 total

15 Oct - 16 Oct

includes taxes & fees

8.6/10 Excellent! (2,738 reviews)

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC

฿2,182

฿2,444 total

15 Oct - 16 Oct

includes taxes & fees

7.2/10 Good! (1,002 reviews)

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

฿2,966

฿3,322 total

20 Oct - 21 Oct

includes taxes & fees

8.4/10 Very good! (391 reviews)

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

฿2,998

฿3,357 total

1 Nov - 2 Nov

includes taxes & fees

9/10 Wonderful! (2,471 reviews)

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

฿3,395

฿3,803 total

8 Nov - 9 Nov

includes taxes & fees

9/10 Wonderful! (1,373 reviews)

The Inn at the Crossroads

128 West Main Street Lake City SC

฿3,897

฿4,365 total

28 Oct - 29 Oct

includes taxes & fees

9.4/10 Exceptional! (1,003 reviews)

Frequently asked questions

Where is the best place to stay in Effingham?

Park Inn by Radisson Florence, SC, located 12.2 mi (19.6 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Howard Johnson by Wyndham Florence and Quality Inn & Suites Florence Civic Center. See all available top hotels, or vacation rentals in Effingham.

If I need to cancel my hotel reservation in Effingham, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.

What's it like to stay in Effingham?

Travellers to Effingham will find plenty to explore and enjoy. There are 160 hotels and other accommodation options in the surrounding area. Find out more about Effingham.

What should I see while I'm in Effingham?

A favourite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Take a look at what more there is to see and do in Expedia's Effingham guide.

What's the seasonal weather in Effingham?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Effingham is 1366 mm.

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Book Hotels in Effingham on Expedia.com

Find hotels in Effingham, SC from ฿2,429

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Effingham

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Effingham hotels

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2. Comfort Inn & Suites Florence Center Area

3. Hyatt Place Florence Downtown

4. Fairfield Inn & Suites by Marriott Florence I-20

5. Homewood Suites by Hilton Florence

6. Staybridge Suites Florence - Civic Center by IHG

7. SpringHill Suites by Marriott Florence

8. Residence Inn Marriott Florence

9. Home2 Suites by Hilton Florence, SC

10. TownePlace Suites by Marriott Florence

11. Hilton Garden Inn Florence

12. Hampton Inn & Suites Florence Center

13. Park Inn by Radisson Florence, SC

14. Hotel Florence, Tapestry Collection by Hilton

15. Tru by Hilton Florence I-95

16. Aloft by Marriott Florence

17. Quality Inn & Suites Florence Civic Center

18. Howard Johnson by Wyndham Florence

19. Courtyard by Marriott Florence

20. Spark by Hilton Florence North I-95, SC

Top Effingham Hotel Reviews

Comfort Inn & Suites Florence Center Area

Spark by Hilton Florence North I-95, SC

Park Inn by Radisson Florence, SC

Aloft by Marriott Florence

The Inn at the Crossroads

Quality Inn & Suites Florence Civic Center

Super 8 by Wyndham Florence

Howard Johnson by Wyndham Florence

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites Florence Civic Center

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

The Inn at the Crossroads

Frequently asked questions

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