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29 Aug - 30 Aug
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30 Aug - 31 Aug
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4 Sep - 6 Sep
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11 Sep - 13 Sep

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Our top choices for Effingham hotels

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A Holiday Inn Express & Suites with a covered outdoor area, brick facade, and a parking lot.
An indoor swimming pool with clear water, marked depth indicators, and safety signs.
A modern conference room with red and grey furniture, a blue pillar, and a mounted television on the wall.

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
฿3,748
฿4,197 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

2. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Brian
฿3,748
฿4,197 total
includes taxes & fees
7 Sept - 8 Sept
Hyatt Place Florence Downtown
A hotel lobby with a reception desk, seating area, and a television screen.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mike
฿3,505
฿3,926 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites Florence Center Area
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.
A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

4. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
Florence
United States
saleh
฿3,367
฿3,902 total
includes taxes & fees
27 Sept - 28 Sept
Home2 Suites by Hilton Florence, SC
A hotel with a modern architectural design, featuring a prominent entrance canopy and a sign indicating it is a Staybridge Suites hotel.
A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.
A hotel lobby with a stone fireplace, recessed lighting, and a large plant.
A modern bathroom with a bathtub, shower, vanity with a mirror, and a towel rack.

5. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Frederick
฿4,438
฿4,970 total
includes taxes & fees
20 Sept - 21 Sept
Staybridge Suites Florence - Civic Center by IHG
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel lobby with a reception desk, seating area, and a welcome mat.

6. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Jennifer
฿3,612
฿4,046 total
includes taxes & fees
20 Sept - 21 Sept
Hampton Inn & Suites Florence Center
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

7. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Hector
฿2,623
฿2,938 total
includes taxes & fees
7 Sept - 8 Sept
Park Inn by Radisson Florence, SC
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

8. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
leslie
฿4,163
฿4,663 total
includes taxes & fees
9 Sept - 10 Sept
Fairfield Inn & Suites by Marriott Florence I-20
An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.
A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.
A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.
A modern lounge area with a fireplace, comfortable seating, and a decorative wall.

9. Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
Florence
United States
Anthony
฿3,532
฿4,284 total
includes taxes & fees
20 Sept - 21 Sept
Homewood Suites by Hilton Florence
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.
A spacious living room with hardwood flooring, a staircase, and a large window.

10. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
฿3,244
฿3,633 total
includes taxes & fees
30 Aug - 31 Aug
The Inn at the Crossroads
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

11. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
Florence
฿2,906
฿3,450 total
includes taxes & fees
20 Sept - 21 Sept
SpringHill Suites by Marriott Florence
A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.
A swimming pool with lounge chairs and a view of the outside.
A hotel lobby with a reception desk, a seating area with green sofas, and a dining area with tables and chairs.
A gym with treadmills, elliptical machines, and free weights.

12. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Florence
United States
Gerson
฿4,073
฿4,889 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel room with a fireplace, a flat-screen TV, a sofa, a patterned carpet, and large windows with a view.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.

13. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
฿2,899
฿3,247 total
includes taxes & fees
27 Sept - 28 Sept
Quality Inn & Suites Florence Civic Center
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

14. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
฿1,928
฿2,159 total
includes taxes & fees
16 Sept - 17 Sept
Howard Johnson by Wyndham Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

15. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United Kingdom
William
฿3,744
฿4,194 total
includes taxes & fees
30 Aug - 31 Aug
TownePlace Suites by Marriott Florence
A restaurant with brick walls, framed awards, and a bar area.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

16. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
฿4,556
฿5,102 total
includes taxes & fees
12 Sept - 13 Sept
Hotel Florence, Tapestry Collection by Hilton
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A corridor with shelves stocked with snacks and a frozen food display.

17. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Michelle
฿3,882
฿4,347 total
includes taxes & fees
8 Sept - 9 Sept
Hampton Inn & Suites Florence-North-I-95
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

18. Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
United States
Jennifer
฿2,906
฿3,386 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Suites Florence I-95
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.
A hotel with a modern design, featuring multiple floors and a parking lot.

19. Residence Inn Marriott Florence

Residence Inn Marriott Florence
Florence
United States
TERRENCE
฿3,550
฿3,975 total
includes taxes & fees
13 Sept - 14 Sept
Residence Inn Marriott Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A Country Inn & Suites by Radisson building with a parking lot and palm trees.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

20. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Francisco
฿3,073
฿3,572 total
includes taxes & fees
13 Sept - 14 Sept
Spark by Hilton Florence North I-95, SC
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Top Effingham Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

8/10 Good
"Clean, updated room. Comfortable bed. Free breakfast. Conveniently off interstate. Food options close/delivered."
Susan 1-night trip
Posted 3 hours ago
Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good
"Nice, comfortable place to stay for one night. The carpets were a little frayed but the hotel was clean and spacious. The breakfast was very good for a continental breakfast."
Patricia H 1-night trip
Posted 4 hours ago
Comfort Inn & Suites Florence Center Area
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Everything was great"
David 1-night trip
Posted 6 hours ago
Howard Johnson by Wyndham Florence
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"Great stay will stay here again"
Telly 1-night trip
Posted 12 hours ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"Staff was friendly. Room was immaculate. Breakfast was delicious. I loved the pancake machine."
Michael 1-night trip
Posted 13 hours ago
Hyatt Place Florence Downtown
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent
"Great location. Clean."
Jane 2-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Florence
The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"Everyone was very nice and everything"
Debra 2-night trip
Posted 3 days ago
The Inn at the Crossroads

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC
฿1,845
฿2,066 total
13 Sept - 14 Sept
includes taxes & fees
Days Inn by Wyndham Florence/I-95 North
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
฿1,928
฿2,159 total
16 Sept - 17 Sept
includes taxes & fees
8.6/10 Excellent! (2,711 reviews)
Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
฿2,623
฿2,938 total
7 Sept - 8 Sept
includes taxes & fees
9/10 Wonderful! (2,406 reviews)
Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
฿2,899
฿3,247 total
27 Sept - 28 Sept
includes taxes & fees
Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
฿3,505
฿3,926 total
20 Sept - 21 Sept
includes taxes & fees
9/10 Wonderful! (1,352 reviews)
Comfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC
฿3,612
฿4,046 total
20 Sept - 21 Sept
includes taxes & fees
Hampton Inn & Suites Florence Center

Frequently asked questions

Where is the best place to stay in Effingham?
Quality Inn & Suites Florence Civic Center, located 10.5 mi (16.9 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Park Inn by Radisson Florence, SC and Howard Johnson by Wyndham Florence. See all available top hotels, or vacation rentals in Effingham.
If I need to cancel my hotel reservation in Effingham, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.
What's it like to stay in Effingham?
Travellers to Effingham will find plenty to explore and enjoy. There are 159 hotels and other accommodation options in the surrounding area. Find out more about Effingham.
What should I see while I'm in Effingham?
A favourite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Take a look at what more there is to see and do in Expedia's Effingham guide.
What's the seasonal weather in Effingham?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Effingham is 1366 mm.

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