Cheap Flights from Mayagüez from ฿3,380

View ฿3,380 flight on Thu, 30 Oct 2025Opens in a new window

Popular airlines from Mayagüez

  • American Airlines

    American Airlines

  • JetBlue Airways

    JetBlue Airways

  • United

    United

  • Delta

    Delta

  • Frontier Airlines

    Frontier Airlines

  • Southwest Airlines

    Southwest Airlines

  • Spirit Airlines

    Spirit Airlines

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 40% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Mayagüez

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿9,925 Return, found 5 days ago
฿9,925
Return
found 5 days ago
Select Copa flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿9,925 found 5 days ago
Copa
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿10,250 Return, found 5 days ago
฿10,250
Return
found 5 days ago
Select Copa flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿10,250 found 5 days ago
Copa
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿10,580 Return, found 5 days ago
฿10,580
Return
found 5 days ago
Select Copa flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿10,580 found 5 days ago
United
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿15,395 Return, found 5 days ago
฿15,395
Return
found 5 days ago
Select United flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿15,395 found 5 days ago
United
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿15,775 Return, found 5 days ago
฿15,775
Return
found 5 days ago
Select United flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿15,775 found 5 days ago
American Airlines
Fri, 31 Oct - Thu, 6 Nov
SJU
San Juan
SDQ
Santo Domingo
฿16,070 Return, found 5 days ago
฿16,070
Return
found 5 days ago
Select American Airlines flight, departing Fri, 31 Oct from San Juan to Santo Domingo, returning Thu, 6 Nov, priced at ฿16,070 found 5 days ago
American Airlines
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿16,115 Return, found 5 days ago
฿16,115
Return
found 5 days ago
Select American Airlines flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿16,115 found 5 days ago
Copa
Fri, 31 Oct - Thu, 6 Nov
SJU
San Juan
SDQ
Santo Domingo
฿16,330 Return, found 5 days ago
฿16,330
Return
found 5 days ago
Select Copa flight, departing Fri, 31 Oct from San Juan to Santo Domingo, returning Thu, 6 Nov, priced at ฿16,330 found 5 days ago
avianca
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿17,140 Return, found 5 days ago
฿17,140
Return
found 5 days ago
Select avianca flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿17,140 found 5 days ago
interCaribbean Airways
Wed, 12 Nov - Thu, 11 Dec
SJU
San Juan
SDQ
Santo Domingo
฿26,575 Return, found 5 days ago
฿26,575
Return
found 5 days ago
Select interCaribbean Airways flight, departing Wed, 12 Nov from San Juan to Santo Domingo, returning Thu, 11 Dec, priced at ฿26,575 found 5 days ago

Travel information

Flights from Mayagüez: Essential Travel Information

Cheapest flight from Mayagüez
฿9,925 (roundtrip)
Best airlines to fly from Mayagüez
Delta, Copa, United, avianca, American Airlines, interCaribbean Airways
Cheapest month to fly from Mayagüez
November
Mayagüez IATA code
SJU
Mayagüez Country/State
Puerto Rico
Airline ticket deals from Mayagüez
฿9,925 - ฿26,575

 

Explore a world of travel with Expedia

*Available to Expedia members.